Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

D2RGN4 (D2RGN4_ARCPA) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ornithine carbamoyltransferase, catabolic HAMAP-Rule MF_01109

Short name=OTCase HAMAP-Rule MF_01109
EC=2.1.3.3 HAMAP-Rule MF_01109
Alternative name(s):
Ornithine carbamoyltransferase HAMAP-Rule MF_01109
Gene names
Name:arcB HAMAP-Rule MF_01109
Ordered Locus Names:Arcpr_0390 EMBL ADB57459.1
OrganismArchaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18) [Complete proteome] [HAMAP] EMBL ADB57459.1
Taxonomic identifier572546 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. HAMAP-Rule MF_01109

Pathway

Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 2/2. HAMAP-Rule MF_01109

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01109.

Sequence similarities

Belongs to the ATCase/OTCase family. HAMAP-Rule MF_01109 RuleBase RU003634

Ontologies

Keywords
   Biological processArginine metabolism HAMAP-Rule MF_01109
   Cellular componentCytoplasm HAMAP-Rule MF_01109
   Molecular functionTransferase HAMAP-Rule MF_01109 RuleBase RU003634 EMBL ADB57459.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginine catabolic process to ornithine

Inferred from electronic annotation. Source: UniProtKB-UniPathway

arginine deiminase pathway

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionamino acid binding

Inferred from electronic annotation. Source: InterPro

ornithine carbamoyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region51 – 555Carbamoyl phosphate binding By similarity HAMAP-Rule MF_01109
Region259 – 2624Ornithine binding By similarity HAMAP-Rule MF_01109

Sites

Binding site1021Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
Binding site1291Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
Site261Important for structural integrity By similarity HAMAP-Rule MF_01109
Site1421Important for structural integrity By similarity HAMAP-Rule MF_01109

Sequences

Sequence LengthMass (Da)Tools
D2RGN4 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: DDA5E61372C3C38C

FASTA30534,595
        10         20         30         40         50         60 
MKHLISMADL TPEELEEILK LAEKLKEERY KGRVTDYLKN KSLAMIFELP STRTRISFEV 

        70         80         90        100        110        120 
AMTDLGGHAL YLNWNDLQLG RGEPIKDTAR VLSRYVHAVM MRVRKHETIL EFAKYSTVPV 

       130        140        150        160        170        180 
INGLSDLEHP CQVIADLLTI KEYKGDLKSV RLTWIGDGNN VCNSLILASA LTGMEMVVCT 

       190        200        210        220        230        240 
PKGYEPNKEI VEKALKMGAK LTFESDPLKA VENADVIYTD VWVSMGQERE RRKRLKAFTG 

       250        260        270        280        290        300 
YQVTQKLVDS AKTNVVVMHC LPAHRGEEIT EEVLEGEHSI VFDQAENRLH AQKAILLKLI 


GKEKE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001857 Genomic DNA. Translation: ADB57459.1.
RefSeqYP_003400132.1. NC_013741.1.

3D structure databases

ProteinModelPortalD2RGN4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB57459; ADB57459; Arcpr_0390.
GeneID8739046.
KEGGapo:Arcpr_0390.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000022686.
KOK00611.
OMAGNNVCNS.

Enzyme and pathway databases

BioCycAPRO572546:GJI1-403-MONOMER.
UniPathwayUPA00254; UER00365.

Family and domain databases

Gene3D3.40.50.1370. 2 hits.
HAMAPMF_01109. OTCase.
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. Orn_carbamltrans.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMSSF53671. SSF53671. 1 hit.
TIGRFAMsTIGR00658. orni_carb_tr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD2RGN4_ARCPA
AccessionPrimary (citable) accession number: D2RGN4
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)