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Protein
Submitted name:

Ornithine carbamoyltransferase

Gene

Arcpr_0390

Organism
Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei78Carbamoyl phosphateUniRule annotation1
Binding sitei102Carbamoyl phosphateUniRule annotation1
Binding sitei160OrnithineUniRule annotation1
Binding sitei220OrnithineUniRule annotation1
Binding sitei288Carbamoyl phosphateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Ornithine carbamoyltransferaseImported (EC:2.1.3.3Imported)
Gene namesi
Ordered Locus Names:Arcpr_0390Imported
OrganismiArchaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)Imported
Taxonomic identifieri572546 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000001901 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi572546.Arcpr_0390.

Structurei

3D structure databases

ProteinModelPortaliD2RGN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 142OTCace_NInterPro annotationAdd BLAST141
Domaini150 – 297OTCaceInterPro annotationAdd BLAST148

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni51 – 54Carbamoyl phosphate bindingUniRule annotation4
Regioni129 – 132Carbamoyl phosphate bindingUniRule annotation4
Regioni224 – 225Ornithine bindingUniRule annotation2
Regioni260 – 261Carbamoyl phosphate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the ATCase/OTCase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00912. Archaea.
COG0078. LUCA.
HOGENOMiHOG000022686.
KOiK00611.
OMAiHPMFLGK.
OrthoDBiPOG093Z05BF.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase. 1 hit.
InterProiView protein in InterPro
IPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. OTCase_ArgI.
PfamiView protein in Pfam
PF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.

Sequencei

Sequence statusi: Complete.

D2RGN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHLISMADL TPEELEEILK LAEKLKEERY KGRVTDYLKN KSLAMIFELP
60 70 80 90 100
STRTRISFEV AMTDLGGHAL YLNWNDLQLG RGEPIKDTAR VLSRYVHAVM
110 120 130 140 150
MRVRKHETIL EFAKYSTVPV INGLSDLEHP CQVIADLLTI KEYKGDLKSV
160 170 180 190 200
RLTWIGDGNN VCNSLILASA LTGMEMVVCT PKGYEPNKEI VEKALKMGAK
210 220 230 240 250
LTFESDPLKA VENADVIYTD VWVSMGQERE RRKRLKAFTG YQVTQKLVDS
260 270 280 290 300
AKTNVVVMHC LPAHRGEEIT EEVLEGEHSI VFDQAENRLH AQKAILLKLI

GKEKE
Length:305
Mass (Da):34,595
Last modified:March 2, 2010 - v1
Checksum:iDDA5E61372C3C38C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001857 Genomic DNA. Translation: ADB57459.1.
RefSeqiWP_012939795.1. NC_013741.1.

Genome annotation databases

EnsemblBacteriaiADB57459; ADB57459; Arcpr_0390.
GeneIDi8739046.
KEGGiapo:Arcpr_0390.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001857 Genomic DNA. Translation: ADB57459.1.
RefSeqiWP_012939795.1. NC_013741.1.

3D structure databases

ProteinModelPortaliD2RGN4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi572546.Arcpr_0390.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB57459; ADB57459; Arcpr_0390.
GeneIDi8739046.
KEGGiapo:Arcpr_0390.

Phylogenomic databases

eggNOGiarCOG00912. Archaea.
COG0078. LUCA.
HOGENOMiHOG000022686.
KOiK00611.
OMAiHPMFLGK.
OrthoDBiPOG093Z05BF.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase. 1 hit.
InterProiView protein in InterPro
IPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. OTCase_ArgI.
PfamiView protein in Pfam
PF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD2RGN4_ARCPA
AccessioniPrimary (citable) accession number: D2RGN4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: June 7, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.