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D2RGN4

- D2RGN4_ARCPA

UniProt

D2RGN4 - D2RGN4_ARCPA

Protein

Ornithine carbamoyltransferase, catabolic

Gene

arcB

Organism
Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (02 Mar 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei26 – 261Important for structural integrityUniRule annotation
    Binding sitei102 – 1021Carbamoyl phosphateUniRule annotation
    Binding sitei129 – 1291Carbamoyl phosphateUniRule annotation
    Sitei142 – 1421Important for structural integrityUniRule annotation

    GO - Molecular functioni

    1. amino acid binding Source: InterPro
    2. ornithine carbamoyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. arginine catabolic process to ornithine Source: UniProtKB-UniPathway
    2. arginine deiminase pathway Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    TransferaseUniRule annotationImported

    Keywords - Biological processi

    Arginine metabolismUniRule annotation

    Enzyme and pathway databases

    BioCyciAPRO572546:GJI1-403-MONOMER.
    UniPathwayiUPA00254; UER00365.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ornithine carbamoyltransferase, catabolicUniRule annotation (EC:2.1.3.3UniRule annotation)
    Short name:
    OTCaseUniRule annotation
    Alternative name(s):
    Ornithine carbamoyltransferaseUniRule annotation
    Gene namesi
    Name:arcBUniRule annotation
    Ordered Locus Names:Arcpr_0390Imported
    OrganismiArchaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)Imported
    Taxonomic identifieri572546 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
    ProteomesiUP000001901: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD2RGN4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni51 – 555Carbamoyl phosphate bindingUniRule annotation
    Regioni259 – 2624Ornithine bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the ATCase/OTCase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000022686.
    KOiK00611.
    OMAiKWAEQNA.

    Family and domain databases

    Gene3Di3.40.50.1370. 2 hits.
    HAMAPiMF_01109. OTCase.
    InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
    IPR006130. Asp/Orn_carbamoylTrfase.
    IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
    IPR002292. Orn/put_carbamltrans.
    IPR024904. Orn_carbamltrans.
    [Graphical view]
    PfamiPF00185. OTCace. 1 hit.
    PF02729. OTCace_N. 1 hit.
    [Graphical view]
    PRINTSiPR00100. AOTCASE.
    PR00102. OTCASE.
    SUPFAMiSSF53671. SSF53671. 1 hit.
    TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D2RGN4-1 [UniParc]FASTAAdd to Basket

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    MKHLISMADL TPEELEEILK LAEKLKEERY KGRVTDYLKN KSLAMIFELP    50
    STRTRISFEV AMTDLGGHAL YLNWNDLQLG RGEPIKDTAR VLSRYVHAVM 100
    MRVRKHETIL EFAKYSTVPV INGLSDLEHP CQVIADLLTI KEYKGDLKSV 150
    RLTWIGDGNN VCNSLILASA LTGMEMVVCT PKGYEPNKEI VEKALKMGAK 200
    LTFESDPLKA VENADVIYTD VWVSMGQERE RRKRLKAFTG YQVTQKLVDS 250
    AKTNVVVMHC LPAHRGEEIT EEVLEGEHSI VFDQAENRLH AQKAILLKLI 300
    GKEKE 305
    Length:305
    Mass (Da):34,595
    Last modified:March 2, 2010 - v1
    Checksum:iDDA5E61372C3C38C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001857 Genomic DNA. Translation: ADB57459.1.
    RefSeqiYP_003400132.1. NC_013741.1.

    Genome annotation databases

    EnsemblBacteriaiADB57459; ADB57459; Arcpr_0390.
    GeneIDi8739046.
    KEGGiapo:Arcpr_0390.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001857 Genomic DNA. Translation: ADB57459.1 .
    RefSeqi YP_003400132.1. NC_013741.1.

    3D structure databases

    ProteinModelPortali D2RGN4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADB57459 ; ADB57459 ; Arcpr_0390 .
    GeneIDi 8739046.
    KEGGi apo:Arcpr_0390.

    Phylogenomic databases

    HOGENOMi HOG000022686.
    KOi K00611.
    OMAi KWAEQNA.

    Enzyme and pathway databases

    UniPathwayi UPA00254 ; UER00365 .
    BioCyci APRO572546:GJI1-403-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1370. 2 hits.
    HAMAPi MF_01109. OTCase.
    InterProi IPR006132. Asp/Orn_carbamoyltranf_P-bd.
    IPR006130. Asp/Orn_carbamoylTrfase.
    IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
    IPR002292. Orn/put_carbamltrans.
    IPR024904. Orn_carbamltrans.
    [Graphical view ]
    Pfami PF00185. OTCace. 1 hit.
    PF02729. OTCace_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00100. AOTCASE.
    PR00102. OTCASE.
    SUPFAMi SSF53671. SSF53671. 1 hit.
    TIGRFAMsi TIGR00658. orni_carb_tr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 5631 / JCM 9629 / NBRC 100127 / Av18Imported.

    Entry informationi

    Entry nameiD2RGN4_ARCPA
    AccessioniPrimary (citable) accession number: D2RGN4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 2, 2010
    Last sequence update: March 2, 2010
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3