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Protein

Ornithine carbamoyltransferase, catabolic

Gene

arcB

Organism
Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei26 – 261Important for structural integrityUniRule annotation
Binding sitei102 – 1021Carbamoyl phosphateUniRule annotation
Binding sitei129 – 1291Carbamoyl phosphateUniRule annotation
Sitei142 – 1421Important for structural integrityUniRule annotation

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. ornithine carbamoyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine catabolic process to ornithine Source: UniProtKB-UniPathway
  2. arginine deiminase pathway Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotation

Keywords - Biological processi

Arginine metabolismUniRule annotation

Enzyme and pathway databases

BioCyciAPRO572546:GJI1-403-MONOMER.
UniPathwayiUPA00254; UER00365.

Names & Taxonomyi

Protein namesi
Recommended name:
Ornithine carbamoyltransferase, catabolicUniRule annotation (EC:2.1.3.3UniRule annotation)
Short name:
OTCaseUniRule annotation
Alternative name(s):
Ornithine carbamoyltransferaseUniRule annotation
Gene namesi
Name:arcBUniRule annotation
Ordered Locus Names:Arcpr_0390Imported
OrganismiArchaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18)Imported
Taxonomic identifieri572546 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
ProteomesiUP000001901 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD2RGN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni51 – 555Carbamoyl phosphate bindingUniRule annotation
Regioni259 – 2624Ornithine bindingUniRule annotation

Sequence similaritiesi

Belongs to the ATCase/OTCase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000022686.
KOiK00611.
OMAiGNNVCNS.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase.
InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. Orn_carbamltrans.
[Graphical view]
PfamiPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.

Sequencei

Sequence statusi: Complete.

D2RGN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHLISMADL TPEELEEILK LAEKLKEERY KGRVTDYLKN KSLAMIFELP
60 70 80 90 100
STRTRISFEV AMTDLGGHAL YLNWNDLQLG RGEPIKDTAR VLSRYVHAVM
110 120 130 140 150
MRVRKHETIL EFAKYSTVPV INGLSDLEHP CQVIADLLTI KEYKGDLKSV
160 170 180 190 200
RLTWIGDGNN VCNSLILASA LTGMEMVVCT PKGYEPNKEI VEKALKMGAK
210 220 230 240 250
LTFESDPLKA VENADVIYTD VWVSMGQERE RRKRLKAFTG YQVTQKLVDS
260 270 280 290 300
AKTNVVVMHC LPAHRGEEIT EEVLEGEHSI VFDQAENRLH AQKAILLKLI

GKEKE
Length:305
Mass (Da):34,595
Last modified:March 1, 2010 - v1
Checksum:iDDA5E61372C3C38C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001857 Genomic DNA. Translation: ADB57459.1.
RefSeqiYP_003400132.1. NC_013741.1.

Genome annotation databases

EnsemblBacteriaiADB57459; ADB57459; Arcpr_0390.
GeneIDi8739046.
KEGGiapo:Arcpr_0390.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001857 Genomic DNA. Translation: ADB57459.1.
RefSeqiYP_003400132.1. NC_013741.1.

3D structure databases

ProteinModelPortaliD2RGN4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB57459; ADB57459; Arcpr_0390.
GeneIDi8739046.
KEGGiapo:Arcpr_0390.

Phylogenomic databases

HOGENOMiHOG000022686.
KOiK00611.
OMAiGNNVCNS.

Enzyme and pathway databases

UniPathwayiUPA00254; UER00365.
BioCyciAPRO572546:GJI1-403-MONOMER.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_01109. OTCase.
InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. Orn_carbamltrans.
[Graphical view]
PfamiPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSiPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00658. orni_carb_tr. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 5631 / JCM 9629 / NBRC 100127 / Av18Imported.

Entry informationi

Entry nameiD2RGN4_ARCPA
AccessioniPrimary (citable) accession number: D2RGN4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2010
Last sequence update: March 1, 2010
Last modified: March 31, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.