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D2RCL2

- D2RCL2_GARV4

UniProt

D2RCL2 - D2RCL2_GARV4

Protein
Submitted name:

Phosphoenolpyruvate carboxykinase (GTP)

Gene

ppc

Organism
Gardnerella vaginalis (strain 409-05)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (02 Mar 2010)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.SAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.SAAS annotation

    Cofactori

    Magnesium.SAAS annotation

    GO - Molecular functioni

    1. kinase activity Source: UniProtKB-KW
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    KinaseImported, LyaseSAAS annotationImported, Transferase

    Keywords - Biological processi

    Carbon dioxide fixationSAAS annotation

    Keywords - Ligandi

    MagnesiumSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciGVAG553190:GJPT-18-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Phosphoenolpyruvate carboxykinase (GTP)Imported (EC:4.1.1.31Imported)
    Gene namesi
    Name:ppcImported
    Ordered Locus Names:HMPREF0424_0018Imported
    OrganismiGardnerella vaginalis (strain 409-05)Imported
    Taxonomic identifieri553190 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeGardnerella
    ProteomesiUP000001888: Chromosome

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000238647.
    KOiK01595.
    OMAiWYGAGSA.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 2 hits.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D2RCL2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATENQQVTP ADATIVTSGL GRKGPEERDL PASLKQDMDL CLHILRDVLG    50
    EFDEKLLAVF DDVRLNAVEA SAAHFAQMVD AKVTADDGLS KAVSKLNGMN 100
    LHDTQLLARA FATYFHLANL CEENYRVSVL HQRECEVEDS LPVDPVNELT 150
    CAYHKLLTEM SPAEAKELLA KLEFHPVFTA HPTEARRKAV AGKIRRISQL 200
    LSEHHRLGGS DKRENYRRLY NEIDALLRTS PIALKKPTPV EESDTILDIF 250
    DATLFDTIPV VYRRFDDWLL GKKAGLVPPR CPAFFHPGSW IGSDRDGNPN 300
    VTAKVSRQVA RKFSDHVLAA LENRTREVGK CLTMETRTTP PSVELLELWN 350
    RQREMSEQLT ENASDVSNSE PHRAVMLVMA DRLHRTISRD TDLMYHSCED 400
    FIEDLQIVQR SLAEGGDPRA AYGPLQDLIW QAQTFGFHMV EMEFRQHSLV 450
    HSRALEDIRE HGLHGERGPL QPMTREVLDT FRALGAIQKR NGMRAARRYI 500
    ISFAKSAQHV RDVFELNRLA FAHPQDAPTI DVIPLFEQLE DLQNSVNVLE 550
    EIIKIPEVQA RLKATGRKME VMLGYSDSSK DAGPTSATLA LHSAQERIAK 600
    WAKKHDIDLT LFHGRGGAVG RGGGPANRAV LAQPVGSVNC RFKLTEQGEV 650
    IFARYGNPIL AIRHVESVAS ATLLQSSPSV EKTNTDMTKK YADMAAKLDV 700
    AAHERFLDLL QTDDFTPWFS TVTPLSEIGL LPIGSRPAKR GLGAKSLDDL 750
    RTIPWVFSWA QARINLAAWY GLGTACEKFG DLETLRRAYE EWPLFSTFID 800
    NIEMSLAKTD ERIARMYLSL GDREDLSDKV LSEMQLTRKW VLQIVDDKWP 850
    LQHRHVLGQA IRVRSPYVDA LSVIQSLALH KLRNKVDKEE LSESQQAEFI 900
    YLILCTVSGV AAGLQNTG 918
    Length:918
    Mass (Da):103,055
    Last modified:March 2, 2010 - v1
    Checksum:iB167FED09002C5BD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001849 Genomic DNA. Translation: ADB14120.1.
    RefSeqiWP_012913687.1. NC_013721.1.
    YP_003373289.1. NC_013721.1.

    Genome annotation databases

    EnsemblBacteriaiADB14120; ADB14120; HMPREF0424_0018.
    GeneIDi8709370.
    KEGGigva:HMPREF0424_0018.
    PATRICi32146038. VBIGarVag136958_0014.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001849 Genomic DNA. Translation: ADB14120.1 .
    RefSeqi WP_012913687.1. NC_013721.1.
    YP_003373289.1. NC_013721.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADB14120 ; ADB14120 ; HMPREF0424_0018 .
    GeneIDi 8709370.
    KEGGi gva:HMPREF0424_0018.
    PATRICi 32146038. VBIGarVag136958_0014.

    Phylogenomic databases

    HOGENOMi HOG000238647.
    KOi K01595.
    OMAi WYGAGSA.
    OrthoDBi EOG6TJ7T8.

    Enzyme and pathway databases

    BioCyci GVAG553190:GJPT-18-MONOMER.

    Family and domain databases

    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 2 hits.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
      Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
      PLoS ONE 5:E12411-E12411(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 409-05Imported.

    Entry informationi

    Entry nameiD2RCL2_GARV4
    AccessioniPrimary (citable) accession number: D2RCL2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 2, 2010
    Last sequence update: March 2, 2010
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3