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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Gardnerella vaginalis (strain 409-05)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.SAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.SAAS annotation

Cofactori

Mg2+SAAS annotation

GO - Molecular functioni

  1. kinase activity Source: UniProtKB-KW
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbon fixation Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, LyaseSAAS annotationImported, Transferase

Keywords - Biological processi

Carbon dioxide fixationSAAS annotation

Keywords - Ligandi

MagnesiumSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciGVAG553190:GJPT-18-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseSAAS annotation (EC:4.1.1.31SAAS annotation)
Gene namesi
Name:ppcImported
Ordered Locus Names:HMPREF0424_0018Imported
OrganismiGardnerella vaginalis (strain 409-05)Imported
Taxonomic identifieri553190 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeGardnerella
ProteomesiUP000001888 Componenti: Chromosome

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2RCL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATENQQVTP ADATIVTSGL GRKGPEERDL PASLKQDMDL CLHILRDVLG
60 70 80 90 100
EFDEKLLAVF DDVRLNAVEA SAAHFAQMVD AKVTADDGLS KAVSKLNGMN
110 120 130 140 150
LHDTQLLARA FATYFHLANL CEENYRVSVL HQRECEVEDS LPVDPVNELT
160 170 180 190 200
CAYHKLLTEM SPAEAKELLA KLEFHPVFTA HPTEARRKAV AGKIRRISQL
210 220 230 240 250
LSEHHRLGGS DKRENYRRLY NEIDALLRTS PIALKKPTPV EESDTILDIF
260 270 280 290 300
DATLFDTIPV VYRRFDDWLL GKKAGLVPPR CPAFFHPGSW IGSDRDGNPN
310 320 330 340 350
VTAKVSRQVA RKFSDHVLAA LENRTREVGK CLTMETRTTP PSVELLELWN
360 370 380 390 400
RQREMSEQLT ENASDVSNSE PHRAVMLVMA DRLHRTISRD TDLMYHSCED
410 420 430 440 450
FIEDLQIVQR SLAEGGDPRA AYGPLQDLIW QAQTFGFHMV EMEFRQHSLV
460 470 480 490 500
HSRALEDIRE HGLHGERGPL QPMTREVLDT FRALGAIQKR NGMRAARRYI
510 520 530 540 550
ISFAKSAQHV RDVFELNRLA FAHPQDAPTI DVIPLFEQLE DLQNSVNVLE
560 570 580 590 600
EIIKIPEVQA RLKATGRKME VMLGYSDSSK DAGPTSATLA LHSAQERIAK
610 620 630 640 650
WAKKHDIDLT LFHGRGGAVG RGGGPANRAV LAQPVGSVNC RFKLTEQGEV
660 670 680 690 700
IFARYGNPIL AIRHVESVAS ATLLQSSPSV EKTNTDMTKK YADMAAKLDV
710 720 730 740 750
AAHERFLDLL QTDDFTPWFS TVTPLSEIGL LPIGSRPAKR GLGAKSLDDL
760 770 780 790 800
RTIPWVFSWA QARINLAAWY GLGTACEKFG DLETLRRAYE EWPLFSTFID
810 820 830 840 850
NIEMSLAKTD ERIARMYLSL GDREDLSDKV LSEMQLTRKW VLQIVDDKWP
860 870 880 890 900
LQHRHVLGQA IRVRSPYVDA LSVIQSLALH KLRNKVDKEE LSESQQAEFI
910
YLILCTVSGV AAGLQNTG
Length:918
Mass (Da):103,055
Last modified:March 2, 2010 - v1
Checksum:iB167FED09002C5BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001849 Genomic DNA. Translation: ADB14120.1.
RefSeqiYP_003373289.1. NC_013721.1.

Genome annotation databases

EnsemblBacteriaiADB14120; ADB14120; HMPREF0424_0018.
KEGGigva:HMPREF0424_0018.
PATRICi32146038. VBIGarVag136958_0014.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001849 Genomic DNA. Translation: ADB14120.1.
RefSeqiYP_003373289.1. NC_013721.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB14120; ADB14120; HMPREF0424_0018.
KEGGigva:HMPREF0424_0018.
PATRICi32146038. VBIGarVag136958_0014.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciGVAG553190:GJPT-18-MONOMER.

Family and domain databases

InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
    Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
    PLoS ONE 5:E12411-E12411(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 409-05Imported.

Entry informationi

Entry nameiD2RCL2_GARV4
AccessioniPrimary (citable) accession number: D2RCL2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: April 1, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.