SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D2RBW0

- D2RBW0_GARV4

UniProt

D2RBW0 - D2RBW0_GARV4

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Elongation factor Tu

Gene
tuf, HMPREF0424_1094
Organism
Gardnerella vaginalis (strain 409-05)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi83 – 875GTP By similarityUniRule annotation
Nucleotide bindingi138 – 1414GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciGVAG553190:GJPT-1089-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotationImported
Ordered Locus Names:HMPREF0424_1094Imported
OrganismiGardnerella vaginalis (strain 409-05)Imported
Taxonomic identifieri553190 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeGardnerella
ProteomesiUP000001888: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000229290.
KOiK02358.
OMAiGDHATFG.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2RBW0-1 [UniParc]FASTAAdd to Basket

« Hide

MAKEKYERTK PHVNIGTIGH VDHGKTTLTA AISKVLHGEY PDLNPQYDFD    50
QIDAAPEEKE RGITINIAHI EYQTAERHYA HVDAPGHADY VKNMITGAAQ 100
MDGAILVVAA TDGPMAQTRE HVLLAKQVGV PKILVALNKC DMVDDPELID 150
LVEEEVRDLL EENGFDRDCP VIRTSAYGAL HDDAPDHEKW VETVKELMKA 200
VDEYIPTPTH DLDKPFLMPI EDVFTISGRG TVVTGRVERG KLPINTPVEI 250
VGLRPTQTTT VTSIETFHKQ MDEAEAGDNT GLLLRGINRT DVERGQVVAA 300
PGSVTPHTKF EGEVYVLTKD EGGRHSPFFS NYRPQFYFRT TDVTGVITLP 350
DGVEMVQPGD HATFTVELIQ AIAMEEGLTF AVREGGRTVG SGRVTKILA 399
Length:399
Mass (Da):43,941
Last modified:March 2, 2010 - v1
Checksum:i8168EAA2BCA13D9F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001849 Genomic DNA. Translation: ADB13727.1.
RefSeqiYP_003374295.1. NC_013721.1.

Genome annotation databases

EnsemblBacteriaiADB13727; ADB13727; HMPREF0424_1094.
GeneIDi8709395.
KEGGigva:HMPREF0424_1094.
PATRICi32148000. VBIGarVag136958_0959.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001849 Genomic DNA. Translation: ADB13727.1 .
RefSeqi YP_003374295.1. NC_013721.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADB13727 ; ADB13727 ; HMPREF0424_1094 .
GeneIDi 8709395.
KEGGi gva:HMPREF0424_1094.
PATRICi 32148000. VBIGarVag136958_0959.

Phylogenomic databases

HOGENOMi HOG000229290.
KOi K02358.
OMAi GDHATFG.
OrthoDBi EOG6R5C6X.

Enzyme and pathway databases

BioCyci GVAG553190:GJPT-1089-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
    Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
    PLoS ONE 5:E12411-E12411(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 409-05.

Entry informationi

Entry nameiD2RBW0_GARV4
AccessioniPrimary (citable) accession number: D2RBW0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: June 11, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi