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D2R9R6 (D2R9R6_GARV4) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ribose-5-phosphate isomerase A HAMAP-Rule MF_00170

EC=5.3.1.6 HAMAP-Rule MF_00170
Alternative name(s):
Phosphoriboisomerase A HAMAP-Rule MF_00170
Gene names
Name:rpiA HAMAP-Rule MF_00170 EMBL ADB14073.1
Ordered Locus Names:HMPREF0424_0296 EMBL ADB14073.1
OrganismGardnerella vaginalis (strain 409-05) [Complete proteome] [HAMAP] EMBL ADB14073.1
Taxonomic identifier553190 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeGardnerella

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate By similarity. HAMAP-Rule MF_00170 SAAS SAAS004788

Catalytic activity

D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP-Rule MF_00170 SAAS SAAS004788

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP-Rule MF_00170 SAAS SAAS004788

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00170 SAAS SAAS004788

Sequence similarities

Belongs to the ribose 5-phosphate isomerase family. HAMAP-Rule MF_00170

Ontologies

Keywords
   Molecular functionIsomerase HAMAP-Rule MF_00170 SAAS SAAS004788 EMBL ADB14073.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpentose-phosphate shunt, non-oxidative branch

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribose-5-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region31 – 344Substrate binding By similarity HAMAP-Rule MF_00170
Region87 – 904Substrate binding By similarity HAMAP-Rule MF_00170
Region100 – 1034Substrate binding By similarity HAMAP-Rule MF_00170

Sites

Active site1091Proton acceptor By similarity HAMAP-Rule MF_00170
Binding site1271Substrate By similarity HAMAP-Rule MF_00170

Sequences

Sequence LengthMass (Da)Tools
D2R9R6 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: F9EA50D1E094EAB5

FASTA23225,460
        10         20         30         40         50         60 
MDKAQQDALK KAAGIEAAKI VKNGMMVGLG TGSTVRFLVD ELGRRVKEEG LSFTGVTTSR 

        70         80         90        100        110        120 
RTQEQAEGYG IKILDINEVD HIDVTIDGSD EVDKNFNGIK GGGAALLWEK IVAINSDRIV 

       130        140        150        160        170        180 
WIVDASKVVD TIGKFPLPVE VIPFGSAQVI RKFEKRGYKP VLRLDADGKE VRTDENNFVV 

       190        200        210        220        230 
DLHMERIEHP QELAKDLIET VGVVEHGLFL NMVDTVIVGD PNGPRTLTNP NK 

« Hide

References

[1]"Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential."
Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A.
PLoS ONE 5:E12411-E12411(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 409-05.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001849 Genomic DNA. Translation: ADB14073.1.
RefSeqYP_003373551.1. NC_013721.1.

3D structure databases

ProteinModelPortalD2R9R6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB14073; ADB14073; HMPREF0424_0296.
GeneID8709034.
KEGGgva:HMPREF0424_0296.
PATRIC32146582. VBIGarVag136958_0275.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000276369.
KOK01807.
OMAGACHVQE.
OrthoDBEOG67MF61.

Enzyme and pathway databases

BioCycGVAG553190:GJPT-300-MONOMER.
UniPathwayUPA00115; UER00412.

Family and domain databases

HAMAPMF_00170. Rib_5P_isom_A.
InterProIPR004788. Ribose5P_isomerase_typA.
IPR020672. Ribose5P_isomerase_typA_subgr.
[Graphical view]
PANTHERPTHR11934. PTHR11934. 1 hit.
PfamPF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]
TIGRFAMsTIGR00021. rpiA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD2R9R6_GARV4
AccessionPrimary (citable) accession number: D2R9R6
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: February 19, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)