D2QK37 (D2QK37_SPILD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
D-alanine--D-alanine ligase domain protein EMBL ADB37159.1

Gene names

Ordered Locus Names:

Slin_1108 EMBL ADB37159.1

Organism

Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) [Complete proteome] [HAMAP] EMBL ADB37159.1

Taxonomic identifier

504472 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Bacteroidetes/Chlorobi group › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Spirosoma › Spirosoma linguale

Protein attributes

Sequence length	551 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation By similarity. SAAS SAAS000291
Catalytic activity	ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS000291
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS000291
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS000291
Subcellular location	Cytoplasm By similarity SAAS SAAS000291.
Sequence similarities	Contains 1 ATP-grasp domain. SAAS SAAS000291

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation SAAS SAAS000291 Peptidoglycan synthesis SAAS SAAS000291
Cellular component	Cytoplasm SAAS SAAS000291
Ligand	ATP-binding SAAS SAAS000291 Magnesium SAAS SAAS000291 Manganese SAAS SAAS000291 Metal-binding SAAS SAAS000291 Nucleotide-binding
Molecular function	Ligase SAAS SAAS000291 EMBL ADB37159.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW D-alanine-D-alanine ligase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D2QK37 [UniParc]. Last modified March 2, 2010. Version 1. Checksum: B63B528D14BC5272	FASTA	551	60,944
	10 20 30 40 50 60 MKIGIFFGGP AREREVSFAG GRTALANLDK GLFEPVLVFV DGRGRFRLVS PDFLQSPSLH 70 80 90 100 110 120 DALPQDSSGF SVYDESLAVD TLDAILPELR PEQFRDHFDL AFLAMHGPDC EDGAIQGLLE 130 140 150 160 170 180 WHKMPYTGPG LVGSAVGINK ILQNELIALA NGQKKKTATI SRDDYEQADK AQFFQSLVEH 190 200 210 220 230 240 LGLPIVIKAP HQGSSIGVAI VREADLAQFC RSVEQCFFTM SIQPDGWSKL SGWTSLSGTE 250 260 270 280 290 300 KHELAQKMVS LDSGISFPVV IEQTGEVIKH PADFVARLDA LMAQSSQPIT LASLNAEDEV 310 320 330 340 350 360 LFEEFITGQE FSCGVIQDDD QVAIALPPTE IYNVTSFDFE SKYKLNTTKK RIPVETSLEN 370 380 390 400 410 420 NRKIQLAVAQ VFTRLGINVY SRIDGFLTPA GDVLLHDPNT IPGMSPSSLI FKQMAEIGLN 430 440 450 460 470 480 LANSLTYLIR QSLRERIRTG KDTFHLKHLL AELDAQLAHR KANPLPERVV SFGSGDEEFI 490 500 510 520 530 540 AAKQQYNELA ASGTVRPSLM YIKSKQESHE IPVNLLFKDT IAELETALSQ PRHPLLLETA 550 ELARHITERY V

References

[1]

"The complete chromosome of Spirosoma linguale DSM 74." US DOE Joint Genome Institute (JGI-PGF) Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Mikhailova N., Ovchinnikova G., Saunders E., Brettin T., Detter J.C., Han C., Larimer F. , Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindal B., Schutze A., Schneider S., Goker M., Klenk H.-P., Eisen J.A. Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33905 / DSM 74 / LMG 10896.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001769 Genomic DNA. Translation: ADB37159.1.
RefSeq	YP_003385958.1. NC_013730.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADB37159; ADB37159; Slin_1108.
GeneID	8724841.
KEGG	sli:Slin_1108.
PATRIC	32432109. VBISpiLin97822_1105.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000011592.
KO	K01921.
OMA	IQGLLEW.
Enzyme and pathway databases
BioCyc	SLIN504472:GHKB-1113-MONOMER.
UniPathway	UPA00219.
Family and domain databases
Gene3D	3.30.1490.20. 1 hit. 3.30.470.20. 2 hits. 3.40.50.20. 1 hit.
InterPro	IPR011761. ATP-grasp. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR000291. D-Ala_lig_Van_CS. IPR005905. D_ala_D_ala. IPR011095. Dala_Dala_lig_C. IPR011127. Dala_Dala_lig_N. IPR016185. PreATP-grasp_dom. [Graphical view]
PANTHER	PTHR23132. PTHR23132. 1 hit.
Pfam	PF07478. Dala_Dala_lig_C. 2 hits. PF01820. Dala_Dala_lig_N. 1 hit. [Graphical view]
SUPFAM	SSF52440. PreATP-grasp-like. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. PS00843. DALA_DALA_LIGASE_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D2QK37_SPILD

Accession

Primary (citable) accession number: D2QK37

Entry history

Integrated into UniProtKB/TrEMBL:	March 2, 2010
Last sequence update:	March 2, 2010
Last modified:	May 29, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)