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D2QK37

- D2QK37_SPILD

UniProt

D2QK37 - D2QK37_SPILD

Protein
Submitted name:

D-alanine--D-alanine ligase domain protein

Gene

Slin_1108

Organism
Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 29 (01 Oct 2014)
      Sequence version 1 (02 Mar 2010)
      Previous versions | rss
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    Functioni

    Cell wall formation.SAAS annotation

    Catalytic activityi

    ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.SAAS annotation

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. D-alanine-D-alanine ligase activity Source: InterPro
    3. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. peptidoglycan biosynthetic process Source: UniProtKB-UniPathway
    2. regulation of cell shape Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseSAAS annotationImported

    Keywords - Biological processi

    Cell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, MagnesiumSAAS annotation, ManganeseSAAS annotation, Metal-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSLIN504472:GHKB-1113-MONOMER.
    UniPathwayiUPA00219.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    D-alanine--D-alanine ligase domain proteinImported
    Gene namesi
    Ordered Locus Names:Slin_1108Imported
    OrganismiSpirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896)Imported
    Taxonomic identifieri504472 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeSpirosoma
    ProteomesiUP000002028: Chromosome

    Subcellular locationi

    Cytoplasm SAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmSAAS annotation

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 ATP-grasp domain.
    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000011592.
    KOiK01921.
    OMAiQGLLEWY.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view]
    PANTHERiPTHR23132. PTHR23132. 1 hit.
    PfamiPF07478. Dala_Dala_lig_C. 2 hits.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF52440. SSF52440. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D2QK37-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKIGIFFGGP AREREVSFAG GRTALANLDK GLFEPVLVFV DGRGRFRLVS    50
    PDFLQSPSLH DALPQDSSGF SVYDESLAVD TLDAILPELR PEQFRDHFDL 100
    AFLAMHGPDC EDGAIQGLLE WHKMPYTGPG LVGSAVGINK ILQNELIALA 150
    NGQKKKTATI SRDDYEQADK AQFFQSLVEH LGLPIVIKAP HQGSSIGVAI 200
    VREADLAQFC RSVEQCFFTM SIQPDGWSKL SGWTSLSGTE KHELAQKMVS 250
    LDSGISFPVV IEQTGEVIKH PADFVARLDA LMAQSSQPIT LASLNAEDEV 300
    LFEEFITGQE FSCGVIQDDD QVAIALPPTE IYNVTSFDFE SKYKLNTTKK 350
    RIPVETSLEN NRKIQLAVAQ VFTRLGINVY SRIDGFLTPA GDVLLHDPNT 400
    IPGMSPSSLI FKQMAEIGLN LANSLTYLIR QSLRERIRTG KDTFHLKHLL 450
    AELDAQLAHR KANPLPERVV SFGSGDEEFI AAKQQYNELA ASGTVRPSLM 500
    YIKSKQESHE IPVNLLFKDT IAELETALSQ PRHPLLLETA ELARHITERY 550
    V 551
    Length:551
    Mass (Da):60,944
    Last modified:March 2, 2010 - v1
    Checksum:iB63B528D14BC5272
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001769 Genomic DNA. Translation: ADB37159.1.
    RefSeqiWP_012925710.1. NC_013730.1.
    YP_003385958.1. NC_013730.1.

    Genome annotation databases

    EnsemblBacteriaiADB37159; ADB37159; Slin_1108.
    GeneIDi8724841.
    KEGGisli:Slin_1108.
    PATRICi32432109. VBISpiLin97822_1105.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001769 Genomic DNA. Translation: ADB37159.1 .
    RefSeqi WP_012925710.1. NC_013730.1.
    YP_003385958.1. NC_013730.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADB37159 ; ADB37159 ; Slin_1108 .
    GeneIDi 8724841.
    KEGGi sli:Slin_1108.
    PATRICi 32432109. VBISpiLin97822_1105.

    Phylogenomic databases

    HOGENOMi HOG000011592.
    KOi K01921.
    OMAi QGLLEWY.

    Enzyme and pathway databases

    UniPathwayi UPA00219 .
    BioCyci SLIN504472:GHKB-1113-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 2 hits.
    3.40.50.20. 1 hit.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR000291. D-Ala_lig_Van_CS.
    IPR005905. D_ala_D_ala.
    IPR011095. Dala_Dala_lig_C.
    IPR011127. Dala_Dala_lig_N.
    IPR016185. PreATP-grasp_dom.
    [Graphical view ]
    PANTHERi PTHR23132. PTHR23132. 1 hit.
    Pfami PF07478. Dala_Dala_lig_C. 2 hits.
    PF01820. Dala_Dala_lig_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52440. SSF52440. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    PS00843. DALA_DALA_LIGASE_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33905 / DSM 74 / LMG 10896Imported.

    Entry informationi

    Entry nameiD2QK37_SPILD
    AccessioniPrimary (citable) accession number: D2QK37
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 2, 2010
    Last sequence update: March 2, 2010
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3