ID   D2QHI6_SPILD            Unreviewed;       397 AA.
AC   D2QHI6;
DT   02-MAR-2010, integrated into UniProtKB/TrEMBL.
DT   02-MAR-2010, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Slin_2629 {ECO:0000313|EMBL:ADB38646.1};
OS   Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896 / Claus 1).
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Spirosoma.
OX   NCBI_TaxID=504472 {ECO:0000313|EMBL:ADB38646.1, ECO:0000313|Proteomes:UP000002028};
RN   [1] {ECO:0000313|Proteomes:UP000002028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33905 / DSM 74 / LMG 10896
RC   {ECO:0000313|Proteomes:UP000002028};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Mikhailova N., Ovchinnikova G., Saunders E., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Tindal B., Schutze A., Schneider S.,
RA   Goker M., Klenk H.-P., Eisen J.A.;
RT   "The complete chromosome of Spirosoma linguale DSM 74.";
RL   Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADB38646.1, ECO:0000313|Proteomes:UP000002028}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33905 / DSM 74 / LMG 10896
RC   {ECO:0000313|Proteomes:UP000002028};
RX   PubMed=21304700;
RA   Lail K., Sikorski J., Saunders E., Lapidus A., Glavina Del Rio T.,
RA   Copeland A., Tice H., Cheng J.-F., Lucas S., Nolan M., Bruce D.,
RA   Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA   Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.-J.,
RA   Jeffries C.D., Chain P., Brettin T., Detter J.C., Schuetze A., Rohde M.,
RA   Tindall B.J., Goeker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.-P., Chen F.;
RT   "Complete genome sequence of Spirosoma linguale type strain (1).";
RL   Stand. Genomic Sci. 2:176-185(2010).
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DR   EMBL; CP001769; ADB38646.1; -; Genomic_DNA.
DR   AlphaFoldDB; D2QHI6; -.
DR   STRING; 504472.Slin_2629; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; sli:Slin_2629; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_1_0_10; -.
DR   Proteomes; UP000002028; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADB38646.1};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          60..373
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   397 AA;  43564 MW;  B6BE26B4D5A2B257 CRC64;
     MLHSFLLAAS LSLSQPLPPA QGIRPDSTTN QPIAETTVFR NGEGGYLCYR IPAIVKTPTG
     TLLAFAEGRR TDCGDFGDVD IVLRTSKDNG QSWSPIQTVV DFGTMQAGNA APVFDVSDPR
     FPAGRLFLLY NTGTDSEANV RKGLAIREVW YKTSTDGGQS WSEPVNITTQ VSRPNRPSVN
     PAYAFPEDWR SYANTPGHAL QLQKGRYKGR IFVAANHSEG PPQQQFRDYR AHGFYSDDHG
     KTWKLSPTIP YPGGNESTAA ETPGGGLLLN ARNQSGDVKN RLLAFSSNAG ESWEPVVVAT
     DLPDPVCQGS MLNYQPRRGA YVLLFSNPNS QTSRTNLTVR VSRDGGKTWS QGNSIYAGSS
     AYSDLVVQQD NTIGVLYEKD NYTKITYARF PYDWLVK
//