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D2QCN7 (D2QCN7_SPILD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA (guanine-N(7)-)-methyltransferase HAMAP-Rule MF_01057
EC=2.1.1.33 HAMAP-Rule MF_01057
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase HAMAP-Rule MF_01057
tRNA(m7G46)-methyltransferase HAMAP-Rule MF_01057
Gene names
Name:trmB HAMAP-Rule MF_01057
Ordered Locus Names:Slin_1997 EMBL ADB38042.1
OrganismSpirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) [Complete proteome] [HAMAP] EMBL ADB38042.1
Taxonomic identifier504472 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Spirosoma ›

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity. HAMAP-Rule MF_01057

Catalytic activity

S-adenosyl-L-methionine + guanine46 in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine46 in tRNA. HAMAP-Rule MF_01057

Pathway

tRNA modification; N(7)-methylguanine-tRNA biosynthesis. HAMAP-Rule MF_01057

Sequence similarities

Belongs to the methyltransferase superfamily. TrmB family. HAMAP-Rule MF_01057

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region197 – 2004Substrate binding By similarity HAMAP-Rule MF_01057

Sites

Binding site471S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site721S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site991S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1211S-adenosyl-L-methionine By similarity HAMAP-Rule MF_01057
Binding site1571Substrate By similarity HAMAP-Rule MF_01057

Sequences

Sequence LengthMass (Da)Tools
D2QCN7 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: 5193DBDCA73C65FA

FASTA22025,050
        10         20         30         40         50         60 
MTRRKSHRFL QNAESTNVIE SGKPLYKTIL GRWRTDFFGN DNPIVLELAC GKGEYTVGLA 

        70         80         90        100        110        120 
QAFPDVNFIG VDIKGDRIAR GSKIAQNLGL SNVAFLRTDI NFLGEFFAKG EINEIWITFP 

       130        140        150        160        170        180 
DPQPRPKQEK HRLTHSRFLA MYQSLLVPGG TLHLKTDNPE LFAYSLEQVQ AAQGRDLQYT 

       190        200        210        220 
TDLYNSPLNE IHLGIKTKYE QIFFDKGFTI NYLQCKMGVI

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001769 Genomic DNA. Translation: ADB38042.1.
RefSeqYP_003386841.1. NC_013730.1.

3D structure databases

ProteinModelPortalD2QCN7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB38042; ADB38042; Slin_1997.
GeneID8725735.
KEGGsli:Slin_1997.
PATRIC32433903. VBISpiLin97822_1998.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000251689.
KOK03439.
OMANINYLEA.

Enzyme and pathway databases

BioCycSLIN504472:GHKB-2438-MONOMER.
UniPathwayUPA00989.

Family and domain databases

HAMAPMF_01057. tRNA_methyltr_TrmB.
InterProIPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamPF02390. Methyltransf_4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00091. TIGR00091. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD2QCN7_SPILD
AccessionPrimary (citable) accession number: D2QCN7
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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