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Protein

Transaldolase

Gene

tal

Organism
Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Transaldolase (tal)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138Schiff-base intermediate with substrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationSAAS annotationImported
Biological processPentose shuntUniRule annotationSAAS annotation
LigandSchiff baseUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotationSAAS annotation (EC:2.2.1.2UniRule annotationSAAS annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:BDP_1144Imported
OrganismiBifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)Imported
Taxonomic identifieri401473 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000008693 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi401473.BDP_1144.

Structurei

3D structure databases

ProteinModelPortaliD2QAD8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QQX. Bacteria.
COG0176. LUCA.
HOGENOMiHOG000226074.
KOiK00616.
OMAiATECYYQ.

Family and domain databases

CDDicd00955. Transaldolase_like. 1 hit.
Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00493. Transaldolase_2. 1 hit.
InterProiView protein in InterPro
IPR013785. Aldolase_TIM.
IPR001585. TAL/FSA.
IPR004732. Transaldolase_2.
IPR018225. Transaldolase_AS.
PANTHERiPTHR10683. PTHR10683. 1 hit.
PTHR10683:SF19. PTHR10683:SF19. 1 hit.
PfamiView protein in Pfam
PF00923. TAL_FSA. 1 hit.
PIRSFiPIRSF036915. Trnald_Bac_Plnt. 1 hit.
TIGRFAMsiTIGR00876. tal_mycobact. 1 hit.
PROSITEiView protein in PROSITE
PS01054. TRANSALDOLASE_1. 1 hit.

Sequencei

Sequence statusi: Complete.

D2QAD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEATQRTSD SGVSIWLDDL SRTRIESGNL QELIKDKNVV GVTTNPSIFQ
60 70 80 90 100
KALSQVGPYD AQLKELGKVD VETAIRELTT TDVRNATDIF REVAEATDFV
110 120 130 140 150
DGRVSIEVDP RLAHETEATE KQAVELWEKV NRPNAMIKIP ATLEGLPAIT
160 170 180 190 200
ATLAKGISVN VTLIFSLERY EQVIDAFIEG IAQADANGHD LNHIGSVASF
210 220 230 240 250
FVSRVDTAVD KQLEEIGSDE AKALEGKAAI ANARLAYELF ENKFANDPRW
260 270 280 290 300
AALEAKGAKK QRPLWASTGT KNPAYSDCVY VDELVAPFIV NTMPEKTLNA
310 320 330 340 350
LADHGNGAPT IKGTYEESHA IMAKLAELGI DFKAVTDKLE ADGVAAFIKS
360
WDSVLTDVQA GIDRVNG
Length:367
Mass (Da):39,875
Last modified:March 2, 2010 - v1
Checksum:iF3D4B25088BB1E3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001750 Genomic DNA. Translation: ADB09774.1.
RefSeqiWP_003840161.1. NC_013714.1.

Genome annotation databases

EnsemblBacteriaiADB09774; ADB09774; BDP_1144.
GeneIDi31606342.
KEGGibde:BDP_1144.

Similar proteinsi

Entry informationi

Entry nameiD2QAD8_BIFDB
AccessioniPrimary (citable) accession number: D2QAD8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: October 25, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported