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Protein

Transaldolase

Gene

tal

Organism
Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381Schiff-base intermediate with substrateUniRule annotation

GO - Molecular functioni

  1. sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationSAAS annotation

Keywords - Biological processi

Pentose shuntUniRule annotationSAAS annotation

Keywords - Ligandi

Schiff baseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBDEN401473:GH09-1114-MONOMER.
UniPathwayiUPA00115; UER00414.
UPA00115; UER00414.

Names & Taxonomyi

Protein namesi
Recommended name:
TransaldolaseUniRule annotationSAAS annotation (EC:2.2.1.2UniRule annotationSAAS annotation)
Gene namesi
Name:talUniRule annotation
Ordered Locus Names:BDP_1144Imported
OrganismiBifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)Imported
Taxonomic identifieri401473 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000008693: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD2QAD8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transaldolase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000226074.
KOiK00616.
OMAiHIHVVAS.
OrthoDBiEOG6T1WSN.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00493. Transaldolase_2.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004732. Transaldolase_2.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
PIRSFiPIRSF036915. Trnald_Bac_Plnt. 1 hit.
TIGRFAMsiTIGR00876. tal_mycobact. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2QAD8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTEATQRTSD SGVSIWLDDL SRTRIESGNL QELIKDKNVV GVTTNPSIFQ
60 70 80 90 100
KALSQVGPYD AQLKELGKVD VETAIRELTT TDVRNATDIF REVAEATDFV
110 120 130 140 150
DGRVSIEVDP RLAHETEATE KQAVELWEKV NRPNAMIKIP ATLEGLPAIT
160 170 180 190 200
ATLAKGISVN VTLIFSLERY EQVIDAFIEG IAQADANGHD LNHIGSVASF
210 220 230 240 250
FVSRVDTAVD KQLEEIGSDE AKALEGKAAI ANARLAYELF ENKFANDPRW
260 270 280 290 300
AALEAKGAKK QRPLWASTGT KNPAYSDCVY VDELVAPFIV NTMPEKTLNA
310 320 330 340 350
LADHGNGAPT IKGTYEESHA IMAKLAELGI DFKAVTDKLE ADGVAAFIKS
360
WDSVLTDVQA GIDRVNG
Length:367
Mass (Da):39,875
Last modified:March 2, 2010 - v1
Checksum:iF3D4B25088BB1E3F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001750 Genomic DNA. Translation: ADB09774.1.
RefSeqiYP_003360598.1. NC_013714.1.

Genome annotation databases

EnsemblBacteriaiADB09774; ADB09774; BDP_1144.
GeneIDi8691944.
KEGGibde:BDP_1144.
PATRICi31956451. VBIBifDen66312_1088.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001750 Genomic DNA. Translation: ADB09774.1.
RefSeqiYP_003360598.1. NC_013714.1.

3D structure databases

ProteinModelPortaliD2QAD8.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB09774; ADB09774; BDP_1144.
GeneIDi8691944.
KEGGibde:BDP_1144.
PATRICi31956451. VBIBifDen66312_1088.

Phylogenomic databases

HOGENOMiHOG000226074.
KOiK00616.
OMAiHIHVVAS.
OrthoDBiEOG6T1WSN.

Enzyme and pathway databases

UniPathwayiUPA00115; UER00414.
UPA00115; UER00414.
BioCyciBDEN401473:GH09-1114-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00493. Transaldolase_2.
InterProiIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004732. Transaldolase_2.
IPR018225. Transaldolase_AS.
[Graphical view]
PANTHERiPTHR10683. PTHR10683. 1 hit.
PfamiPF00923. Transaldolase. 1 hit.
[Graphical view]
PIRSFiPIRSF036915. Trnald_Bac_Plnt. 1 hit.
TIGRFAMsiTIGR00876. tal_mycobact. 1 hit.
PROSITEiPS01054. TRANSALDOLASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27534 / DSM 20436 / JCM 1195 / Bd1Imported.

Entry informationi

Entry nameiD2QAD8_BIFDB
AccessioniPrimary (citable) accession number: D2QAD8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: February 4, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.