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Protein

Glutamate decarboxylase

Gene

gadB

Organism
Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadBImported
Ordered Locus Names:BDP_1749Imported
OrganismiBifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)Imported
Taxonomic identifieri401473 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000008693 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei289N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi401473.BDP_1749.

Structurei

3D structure databases

ProteinModelPortaliD2Q5X3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK. Bacteria.
COG0076. LUCA.
HOGENOMiHOG000070228.
KOiK01580.
OMAiRPNLVMG.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiView protein in InterPro
IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_sub2.
PANTHERiPTHR43321. PTHR43321. 1 hit.
PfamiView protein in Pfam
PF00282. Pyridoxal_deC. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

D2Q5X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIMHSNINT IAAGYGYSGG ADSDSVEVNP LFARPKEAKA FSKFKIPQEG
60 70 80 90 100
SLPETAYQVV HDDAMLDGNA RLNLATFVST WMDDYANRLY MEAADKNMID
110 120 130 140 150
KDEYPKTAEV ESRCWHMLAD LWHAPDPMNT IGTSTIGSSE ACMLGGLALK
160 170 180 190 200
RRWKEAREKA GLPADRPNLV MSSAVQVCWE KFCNYFDVEP RYVPISEEHK
210 220 230 240 250
VLDGYDLDKY VDENTIGVVA IMGVTYTGMY EPVKKISDAL DRIEERTGLD
260 270 280 290 300
VRIHVDAASG GMIAPFIQPD LQWDFRVKRV YSISTSGHKY GLVYPGLGWV
310 320 330 340 350
VWRETADLPE SLIFKVSYLG GEMPTFALNF SRPGAQVLLQ YYMFLRLGFE
360 370 380 390 400
GYRRVQQAAH DVAKYLSGEI AKMDDFTLWN DGSDIPVFAW MLKDKPDRKW
410 420 430 440 450
NLYDLQDRLR MKGWLVPAYP MPVDLTQVTV QRIVVRNGFS HDMAESFLKD
460 470
LKACVKYLDG LKAPMPSEAR VSGFHH
Length:476
Mass (Da):53,864
Last modified:March 2, 2010 - v1
Checksum:i8E97A12B3159B6FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001750 Genomic DNA. Translation: ADB10338.1.
RefSeqiWP_003839070.1. NC_013714.1.

Genome annotation databases

EnsemblBacteriaiADB10338; ADB10338; BDP_1749.
GeneIDi31606910.
KEGGibde:BDP_1749.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD2Q5X3_BIFDB
AccessioniPrimary (citable) accession number: D2Q5X3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: July 5, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported