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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene

Kfla_5184

Organism
Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  2. thiamine pyrophosphate binding Source: InterPro
  3. transferase activity, transferring acyl groups Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciKFLA479435:GI0F-5228-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported
Gene namesi
Ordered Locus Names:Kfla_5184Imported
OrganismiKribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)Imported
Taxonomic identifieri479435 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaeNocardioidaceaeKribbella
ProteomesiUP000007967: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD2Q4U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000259587.
KOiK00164.
OMAiFGEQDME.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

D2Q4U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATEPSDTNP LAAFGSNEWL VDEMYEKYQQ DPKSVDPAWQ TYFESDGFKG
60 70 80 90 100
SGPGDAKPVT TGPADAPRPD AVSDNKTPEA AVRGTTATAP AASKPAAQAA
110 120 130 140 150
ARTPEQAAPP TTASTAQPAQ SRPAQTQPPA SAQQTAPAAS GAPTGGTVNQ
160 170 180 190 200
PPSAQPKPAP ATSTDAERKV LRGAPARTAQ NMETSLQVPT ATSVRQVPVK
210 220 230 240 250
LLIDNRIVIN NHLKRARGGK ISFTHLIGWA LVKALKTLPE MNASYDETEG
260 270 280 290 300
KPTLVQPAHI NLGLAIDMAK PDGTRQLLVP SIKAAETMTF AEFWMAYEDI
310 320 330 340 350
VRRARDNKLA LPDFQGTTIS LTNPGTIGTQ HSVPRLMSGQ GCIIGVGAME
360 370 380 390 400
YPPEYQGAAE ETMAKLAVSK VMTLTSTYDH RIIQGAQSGE FLRKIHQLLL
410 420 430 440 450
GEEGFYDEIF QSLRIPYEPI RWAADLPHSH EEDISKQARI LELIHAYRVR
460 470 480 490 500
GHIMADTDPL EYKQRSHPDL DVATHGLTLW DLDREFATGS FGAATDRRFM
510 520 530 540 550
KLREILGILR DSYCRTTGVE YMHIQDPEQR KWLQERIERP HTKPPREEQL
560 570 580 590 600
RILAKLNEAE AFETFLQTKY VGQKRFSLEG GETTIPLLDE LCEEAAGAGL
610 620 630 640 650
DEVVIGMAHR GRLNVLANIV GKSYGQIFRE FDGNIDPRTV QGSGDVKYHL
660 670 680 690 700
GAEGEFVSEF GDKIKVSVAA NPSHLETVDP VLEGIVRAKQ DILDRGAAFP
710 720 730 740 750
VLPVLVHGDA AFAGQGVVAE TLNLSQLRGY RTGGTIHVIV NNQVGFTTSP
760 770 780 790 800
ASSRSSMYCT DVARMVQAPI FHVNGDDPEA CIRVASLAFE YRQAFNKDVV
810 820 830 840 850
IDLVCYRRRG HNEGDDPSFT QPLMYDLIEQ KRSVRKLYTE ALIGRGDITV
860 870 880 890 900
EEAEQAMRDF QQRLERVFTE VREAKSQPDT PAPYVTVPVY PDKPEGPDAT
910 920 930 940 950
ATTPEVLKKI ADAYTTLPEG FTAHPKVLPQ LQRRAAAITQ GPVDWASAEI
960 970 980 990 1000
TAFGSLLLAG RPVRLAGQDS RRGTFVQRFA AIIDRVNGQD HVPLQHLGED
1010 1020 1030 1040 1050
QANFYVYDSL LSEYAALGFE YGYSVARPDA LVLWEAQFGD FVNGAQSIID
1060 1070 1080 1090 1100
EYISAGEAKW GQKSGVVLLL PHGYEGQGPD HSSARIERFL TLCAENAMTV
1110 1120 1130 1140 1150
AQPSTPASYF HLLRRHTLQE EHNPLIVFTP KQLLRRKEAV SQPEELTSGS
1160 1170 1180 1190 1200
FRPVLNDSDA EQNPATVERV ILASGRISYD LLAERKKVEP DKISTAVLRV
1210 1220 1230 1240 1250
EQLYPLPTEQ IKAELAKYPN ATEIRWVQDE PANQGPWPFM ALNLTEHLGG
1260 1270 1280
KPFYRVSRPA MSAPSVGSMG VHQAEQATLL KQAFS
Length:1,285
Mass (Da):141,182
Last modified:March 2, 2010 - v1
Checksum:i870E6A9418019FA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB34199.1.
RefSeqiYP_003382998.1. NC_013729.1.

Genome annotation databases

EnsemblBacteriaiADB34199; ADB34199; Kfla_5184.
GeneIDi8721805.
KEGGikfl:Kfla_5184.
PATRICi32240851. VBIKriFla67707_5181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB34199.1.
RefSeqiYP_003382998.1. NC_013729.1.

3D structure databases

ProteinModelPortaliD2Q4U4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB34199; ADB34199; Kfla_5184.
GeneIDi8721805.
KEGGikfl:Kfla_5184.
PATRICi32240851. VBIKriFla67707_5181.

Phylogenomic databases

HOGENOMiHOG000259587.
KOiK00164.
OMAiFGEQDME.

Enzyme and pathway databases

BioCyciKFLA479435:GI0F-5228-MONOMER.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17836 / JCM 10339 / NBRC 14399Imported.

Entry informationi

Entry nameiD2Q4U4_KRIFD
AccessioniPrimary (citable) accession number: D2Q4U4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: March 4, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.