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UniProtKB - D2Q4U4 (D2Q4U4_KRIFD)

UniProt

D2Q4U4 - D2Q4U4_KRIFD

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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene

Kfla_5184

Organism
Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciKFLA479435:GI0F-5228-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported
Gene namesi
Ordered Locus Names:Kfla_5184Imported
OrganismiKribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)Imported
Taxonomic identifieri479435 [NCBI]
Taxonomic lineageiBacteria › Actinobacteria › Propionibacteriales › Nocardioidaceae › Kribbella ›
Proteomesi
  • UP000007967 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi479435.Kfla_5184.

Structurei

3D structure databases

ProteinModelPortaliD2Q4U4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini943 – 1136194Transket_pyrInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili850 – 87728Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105C7P. Bacteria.
COG0508. LUCA.
COG0567. LUCA.
HOGENOMiHOG000259587.
KOiK00164.
OMAiYEPIRWA.
OrthoDBiPOG091H03SK.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR032106. 2-oxogl_dehyd_N.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR031717. KGD_C.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF16078. 2-oxogl_dehyd_N. 1 hit.
PF00676. E1_dh. 1 hit.
PF16870. OxoGdeHyase_C. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

D2Q4U4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATEPSDTNP LAAFGSNEWL VDEMYEKYQQ DPKSVDPAWQ TYFESDGFKG 
        60         70         80         90        100
SGPGDAKPVT TGPADAPRPD AVSDNKTPEA AVRGTTATAP AASKPAAQAA 
       110        120        130        140        150
ARTPEQAAPP TTASTAQPAQ SRPAQTQPPA SAQQTAPAAS GAPTGGTVNQ 
       160        170        180        190        200
PPSAQPKPAP ATSTDAERKV LRGAPARTAQ NMETSLQVPT ATSVRQVPVK 
       210        220        230        240        250
LLIDNRIVIN NHLKRARGGK ISFTHLIGWA LVKALKTLPE MNASYDETEG 
       260        270        280        290        300
KPTLVQPAHI NLGLAIDMAK PDGTRQLLVP SIKAAETMTF AEFWMAYEDI 
       310        320        330        340        350
VRRARDNKLA LPDFQGTTIS LTNPGTIGTQ HSVPRLMSGQ GCIIGVGAME 
       360        370        380        390        400
YPPEYQGAAE ETMAKLAVSK VMTLTSTYDH RIIQGAQSGE FLRKIHQLLL 
       410        420        430        440        450
GEEGFYDEIF QSLRIPYEPI RWAADLPHSH EEDISKQARI LELIHAYRVR 
       460        470        480        490        500
GHIMADTDPL EYKQRSHPDL DVATHGLTLW DLDREFATGS FGAATDRRFM 
       510        520        530        540        550
KLREILGILR DSYCRTTGVE YMHIQDPEQR KWLQERIERP HTKPPREEQL 
       560        570        580        590        600
RILAKLNEAE AFETFLQTKY VGQKRFSLEG GETTIPLLDE LCEEAAGAGL 
       610        620        630        640        650
DEVVIGMAHR GRLNVLANIV GKSYGQIFRE FDGNIDPRTV QGSGDVKYHL 
       660        670        680        690        700
GAEGEFVSEF GDKIKVSVAA NPSHLETVDP VLEGIVRAKQ DILDRGAAFP 
       710        720        730        740        750
VLPVLVHGDA AFAGQGVVAE TLNLSQLRGY RTGGTIHVIV NNQVGFTTSP 
       760        770        780        790        800
ASSRSSMYCT DVARMVQAPI FHVNGDDPEA CIRVASLAFE YRQAFNKDVV 
       810        820        830        840        850
IDLVCYRRRG HNEGDDPSFT QPLMYDLIEQ KRSVRKLYTE ALIGRGDITV 
       860        870        880        890        900
EEAEQAMRDF QQRLERVFTE VREAKSQPDT PAPYVTVPVY PDKPEGPDAT 
       910        920        930        940        950
ATTPEVLKKI ADAYTTLPEG FTAHPKVLPQ LQRRAAAITQ GPVDWASAEI 
       960        970        980        990       1000
TAFGSLLLAG RPVRLAGQDS RRGTFVQRFA AIIDRVNGQD HVPLQHLGED 
      1010       1020       1030       1040       1050
QANFYVYDSL LSEYAALGFE YGYSVARPDA LVLWEAQFGD FVNGAQSIID 
      1060       1070       1080       1090       1100
EYISAGEAKW GQKSGVVLLL PHGYEGQGPD HSSARIERFL TLCAENAMTV 
      1110       1120       1130       1140       1150
AQPSTPASYF HLLRRHTLQE EHNPLIVFTP KQLLRRKEAV SQPEELTSGS 
      1160       1170       1180       1190       1200
FRPVLNDSDA EQNPATVERV ILASGRISYD LLAERKKVEP DKISTAVLRV 
      1210       1220       1230       1240       1250
EQLYPLPTEQ IKAELAKYPN ATEIRWVQDE PANQGPWPFM ALNLTEHLGG 
      1260       1270       1280 
KPFYRVSRPA MSAPSVGSMG VHQAEQATLL KQAFS
Length:1,285
Mass (Da):141,182
Last modified:March 2, 2010 - v1
Checksum:i870E6A9418019FA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB34199.1.
RefSeqiWP_012922753.1. NC_013729.1.

Genome annotation databases

EnsemblBacteriaiADB34199; ADB34199; Kfla_5184.
KEGGikfl:Kfla_5184.
PATRICi32240851. VBIKriFla67707_5181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB34199.1.
RefSeqiWP_012922753.1. NC_013729.1.

3D structure databases

ProteinModelPortaliD2Q4U4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi479435.Kfla_5184.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB34199; ADB34199; Kfla_5184.
KEGGikfl:Kfla_5184.
PATRICi32240851. VBIKriFla67707_5181.

Phylogenomic databases

eggNOGiENOG4105C7P. Bacteria.
COG0508. LUCA.
COG0567. LUCA.
HOGENOMiHOG000259587.
KOiK00164.
OMAiYEPIRWA.
OrthoDBiPOG091H03SK.

Enzyme and pathway databases

BioCyciKFLA479435:GI0F-5228-MONOMER.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
3.40.50.970. 2 hits.
InterProiIPR001078. 2-oxoacid_DH_actylTfrase.
IPR032106. 2-oxogl_dehyd_N.
IPR011603. 2oxoglutarate_DH_E1.
IPR023213. CAT-like_dom.
IPR001017. DH_E1.
IPR031717. KGD_C.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF16078. 2-oxogl_dehyd_N. 1 hit.
PF00676. E1_dh. 1 hit.
PF16870. OxoGdeHyase_C. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD2Q4U4_KRIFD
AccessioniPrimary (citable) accession number: D2Q4U4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: September 7, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.