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Protein

Aldose 1-epimerase

Gene

Kfla_6341

Organism
Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathway: hexose metabolism

This protein is involved in the pathway hexose metabolism, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway hexose metabolism and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciKFLA479435:GI0F-6398-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Ordered Locus Names:Kfla_6341Imported
OrganismiKribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)Imported
Taxonomic identifieri479435 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPropionibacterialesNocardioidaceaeKribbella
ProteomesiUP000007967 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3434 PotentialImportedAdd
BLAST
Chaini35 – 403369 PotentialImportedPRO_5000560443Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi479435.Kfla_6341.

Structurei

3D structure databases

ProteinModelPortaliD2PWW3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

HOGENOMiHOG000072798.
KOiK01785.
OMAiFNLDGDQ.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006311. TAT_signal.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D2PWW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDHLPRRHV LRTAGALGLG AAAAGALTGP ADAAPTATTV ASMGSHHGRL
60 70 80 90 100
SIRKDPFGTT PEGVGVDVYT FGNGRVTVSM LTWGATIQRV ETPDRRGRTE
110 120 130 140 150
NISLGFDNLP DYAALSPYFG ATIGRYGNRI AKGRFTLDGR SYQIPVNNGE
160 170 180 190 200
NALHGGTLGF DKKVWKAKVV QTPSAVGVAF SYVSPDGEMG FPGELTTTVT
210 220 230 240 250
YTLNKQDDLR IDYHATVAGK PTVVNLTNHV YFNLAGEGSG SIDGHVLQLN
260 270 280 290 300
APSYTPVDEG LIPTGEIAPV AGTPFDFNRP TAIGARIRDD HPQLVIGRGY
310 320 330 340 350
DHNFVLGGKP DRDGLRFAAR FWEPEGGRTV TVHTAEPGAQ FYSGNFLDGT
360 370 380 390 400
FQGIGNKSYR QGDAFAFETQ HFPDSPNHPN FPSTVLRPGE TYRSTTVYSF

GTK
Length:403
Mass (Da):43,215
Last modified:March 2, 2010 - v1
Checksum:i14CCBC1037F32119
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB35343.1.
RefSeqiWP_012923896.1. NC_013729.1.
YP_003384142.1. NC_013729.1.

Genome annotation databases

EnsemblBacteriaiADB35343; ADB35343; Kfla_6341.
KEGGikfl:Kfla_6341.
PATRICi32243210. VBIKriFla67707_6347.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB35343.1.
RefSeqiWP_012923896.1. NC_013729.1.
YP_003384142.1. NC_013729.1.

3D structure databases

ProteinModelPortaliD2PWW3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi479435.Kfla_6341.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB35343; ADB35343; Kfla_6341.
KEGGikfl:Kfla_6341.
PATRICi32243210. VBIKriFla67707_6347.

Phylogenomic databases

HOGENOMiHOG000072798.
KOiK01785.
OMAiFNLDGDQ.

Enzyme and pathway databases

UniPathwayiUPA00242.
BioCyciKFLA479435:GI0F-6398-MONOMER.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006311. TAT_signal.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17836 / JCM 10339 / NBRC 14399Imported.

Entry informationi

Entry nameiD2PWW3_KRIFD
AccessioniPrimary (citable) accession number: D2PWW3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: June 24, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.