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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei151 – 1511UniRule annotation
Active sitei544 – 5441UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciKFLA479435:GI0F-1457-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Kfla_1442Imported
OrganismiKribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)Imported
Taxonomic identifieri479435 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPropionibacterialesNocardioidaceaeKribbella
ProteomesiUP000007967 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi479435.Kfla_1442.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2PKN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTETGSQASA RTRTRARFEV PEELRADVRL LGEILGRVLV EYAGQPLLDD
60 70 80 90 100
VEKLRELTIA GDGEAAEQLV ASWPHERAED VARAFTCYFH LTNLSEELHR
110 120 130 140 150
ARVLRERDRS GDAPAVSELA QAVERISADA GEQQARALLN GLEFRPVLTA
160 170 180 190 200
HPTEARRRAV LATIRRISSL LEERNDPRAG DSELAENRRR LVEQVDILWR
210 220 230 240 250
TSQLRTSRPT PLDEVRSAMA VFEETLFDVV GNVYRRLDDA LAGDAAGTRP
260 270 280 290 300
PVVAPFVRLG SWIGGDRDGN PNVTAAITRE AMQIQADHVL RALEQATDEL
310 320 330 340 350
GRALTLDAAT TPPSAPVRRI LEDARAANPA LIADIETRSP SEPHRQLLLL
360 370 380 390 400
AARRLAATRS RDADFGYPRA ADFLHELKVL QDSLVSAGAP RQAYGQLQQL
410 420 430 440 450
IWQVSSFGFH LAELEVRQHS SVHAKALEEV LGGGELSDQT EEVLATLRVI
460 470 480 490 500
GQIQQRFGPE ACRRYVVSFT RSAADLAAVY ELADAAMDGR PIELDVVPLF
510 520 530 540 550
ETGEDLQNSV EVLDNAIQLT RVRHRLTAND RRFEVMLGYS DSAKDVGPVS
560 570 580 590 600
ATLALYDAQA RITAWAQRNA IRLTLFHGRG GALGRGGGPA NRAVLAQAPG
610 620 630 640 650
SVGGRFKLTE QGEAIPARYG NAPIAQRHIE QVTAATLLAS TPAVEDRAAA
660 670 680 690 700
AANRFAVVEK TLDEAARTAY HRLVKADGFA EWFGRVTPLE ELGQLPLGSR
710 720 730 740 750
PARRGVAVSS LEDLRAIPWV FAWSQARVNA PGWYGLGSAL AAVGDVAVLQ
760 770 780 790 800
DANKNWPLFQ VMLENAEMSL AKTDRRILGR YLELGDRPDL SQLMLDEHAL
810 820 830 840 850
TTEWVLKVLD GDRLLAGRRV LGRAVELRNP YVDALSYLQL RALRDLRTDD
860 870
SLDEQQIVRT RRLLLLTVSG VAAGLQNTG
Length:879
Mass (Da):96,507
Last modified:March 2, 2010 - v1
Checksum:i22053730EE5A103F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB30543.1.
RefSeqiWP_012919099.1. NC_013729.1.

Genome annotation databases

EnsemblBacteriaiADB30543; ADB30543; Kfla_1442.
KEGGikfl:Kfla_1442.
PATRICi32233309. VBIKriFla67707_1437.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001736 Genomic DNA. Translation: ADB30543.1.
RefSeqiWP_012919099.1. NC_013729.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi479435.Kfla_1442.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB30543; ADB30543; Kfla_1442.
KEGGikfl:Kfla_1442.
PATRICi32233309. VBIKriFla67707_1437.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciKFLA479435:GI0F-1457-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 2 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17836 / JCM 10339 / NBRC 14399Imported.

Entry informationi

Entry nameiD2PKN1_KRIFD
AccessioniPrimary (citable) accession number: D2PKN1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: July 22, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.