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D2PCI6 (D2PCI6_SULID) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Imidazoleglycerol-phosphate dehydratase HAMAP-Rule MF_00076

Short name=IGPD HAMAP-Rule MF_00076
EC=4.2.1.19 HAMAP-Rule MF_00076
Gene names
Name:hisB HAMAP-Rule MF_00076
Ordered Locus Names:LD85_1744 EMBL ADB87406.1
OrganismSulfolobus islandicus (strain L.D.8.5 / Lassen #2) [Complete proteome] [HAMAP] EMBL ADB87406.1
Taxonomic identifier425944 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O. HAMAP-Rule MF_00076

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9. HAMAP-Rule MF_00076

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00076.

Sequence similarities

Belongs to the imidazoleglycerol-phosphate dehydratase family. HAMAP-Rule MF_00076

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Histidine biosynthesis HAMAP-Rule MF_00076
   Cellular componentCytoplasm HAMAP-Rule MF_00076
   Molecular functionLyase HAMAP-Rule MF_00076
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processhistidine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionimidazoleglycerol-phosphate dehydratase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D2PCI6 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: 0368FB1F03D1FE58

FASTA19321,513
        10         20         30         40         50         60 
MARNANITRE TKETKIEVFL DIDRKGEIKV STPVPFFNHM LITLLTYMNS TATVSATDKL 

        70         80         90        100        110        120 
PYDDHHIIED VAITLGLAIK EALGDKRGIK RFSHQIIPMD EALVLVSLDI SNRGMAFVSL 

       130        140        150        160        170        180 
NLRRSEIGGL ATENIPHFFQ SFAYNSGVTL HISQLSGYNT HHIIEASFKA LGLALYEATR 

       190 
IVDNEIRSTK GVI 

« Hide

References

[1]"Biogeography of the Sulfolobus islandicus pan-genome."
Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.
Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L.D.8.5 / Lassen #2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001731 Genomic DNA. Translation: ADB87406.1.
RefSeqYP_003419776.1. NC_013769.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADB87406; ADB87406; LD85_1744.
GeneID8761573.
KEGGsii:LD85_1744.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000228064.
KOK01693.
OMACTAATGI.

Enzyme and pathway databases

BioCycSISL425944:GHS5-1734-MONOMER.
UniPathwayUPA00031; UER00011.

Family and domain databases

HAMAPMF_00076. HisB.
InterProIPR000807. ImidazoleglycerolP_deHydtase.
IPR020565. ImidazoleglycerP_deHydtase_CS.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERPTHR23133:SF2. PTHR23133:SF2. 1 hit.
PfamPF00475. IGPD. 1 hit.
[Graphical view]
SUPFAMSSF54211. SSF54211. 2 hits.
PROSITEPS00954. IGP_DEHYDRATASE_1. 1 hit.
PS00955. IGP_DEHYDRATASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2PCI6_SULID
AccessionPrimary (citable) accession number: D2PCI6
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: May 14, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)