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Protein

2,3-bisphosphoglycerate-dependent phosphoglycerate mutase

Gene

gpmA

Organism
Listeria monocytogenes serotype 1/2a (strain 08-5578)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.UniRule annotation

Catalytic activityi

2-phospho-D-glycerate = 3-phospho-D-glycerate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei8 – 81Tele-phosphohistidine intermediateUniRule annotation
Binding sitei14 – 1412-phospho-D-glycerateUniRule annotation
Binding sitei59 – 5912-phospho-D-glycerateUniRule annotation
Binding sitei97 – 9712-phospho-D-glycerateUniRule annotation
Active sitei181 – 1811UniRule annotation
Binding sitei183 – 18312-phospho-D-glycerateUniRule annotation

GO - Molecular functioni

  1. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciLMON653938:GJ8G-2444-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutaseUniRule annotation (EC:5.4.2.11UniRule annotation)
Short name:
BPG-dependent PGAMUniRule annotation
Short name:
PGAMUniRule annotation
Short name:
PhosphoglyceromutaseUniRule annotation
Short name:
dPGMUniRule annotation
Gene namesi
Name:gpmAUniRule annotation
Ordered Locus Names:LM5578_2408Imported
OrganismiListeria monocytogenes serotype 1/2a (strain 08-5578)Imported
Taxonomic identifieri653938 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000001900: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD2NWV8.
SMRiD2NWV8. Positions 2-227.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 2122-phospho-D-glycerate bindingUniRule annotation
Regioni86 – 8942-phospho-D-glycerate bindingUniRule annotation
Regioni113 – 11422-phospho-D-glycerate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000221682.
KOiK01834.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2NWV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLVLIRHGQ SEWNKLNLFT GWHDVDLSQE GVVEAMTAGK RIKEAGLEFD
60 70 80 90 100
VAFTSVLTRA IKTLNYVLEE SDQMWVPVHK SWRLNERHYG ALQGLNKQET
110 120 130 140 150
AEKYGADQVQ KWRRSYDTLP PLLEENDERQ AKNDRRYQLL DTHAIPSGEN
160 170 180 190 200
LKVTLERVIP YWMDTIAPEI KEGRRVVIAA HGNSLRALVK FLEGISDDEI
210 220
MDLEIPTGVP LVYELNDDLK PVNKYYLDK
Length:229
Mass (Da):26,461
Last modified:March 2, 2010 - v1
Checksum:i3073F6E8CAEDEFE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001602 Genomic DNA. Translation: ADB69155.1.
RefSeqiYP_003414517.1. NC_013766.2.

Genome annotation databases

EnsemblBacteriaiADB69155; ADB69155; LM5578_2408.
GeneIDi8749391.
KEGGilmn:LM5578_2408.
PATRICi35279350. VBILisMon159512_2425.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001602 Genomic DNA. Translation: ADB69155.1.
RefSeqiYP_003414517.1. NC_013766.2.

3D structure databases

ProteinModelPortaliD2NWV8.
SMRiD2NWV8. Positions 2-227.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB69155; ADB69155; LM5578_2408.
GeneIDi8749391.
KEGGilmn:LM5578_2408.
PATRICi35279350. VBILisMon159512_2425.

Phylogenomic databases

HOGENOMiHOG000221682.
KOiK01834.

Enzyme and pathway databases

BioCyciLMON653938:GJ8G-2444-MONOMER.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
HAMAPiMF_01039. PGAM_GpmA.
InterProiIPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR001345. PG/BPGM_mutase_AS.
IPR005952. Phosphogly_mut1.
[Graphical view]
PANTHERiPTHR11931. PTHR11931. 1 hit.
PfamiPF00300. His_Phos_1. 1 hit.
[Graphical view]
SMARTiSM00855. PGAM. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
TIGRFAMsiTIGR01258. pgm_1. 1 hit.
PROSITEiPS00175. PG_MUTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-throughput genome sequencing of two Listeria monocytogenes clinical isolates during a large foodborne outbreak."
    Gilmour M.W., Graham M., Van Domselaar G., Tyler S., Kent H., Trout-Yakel K.M., Larios O., Allen V., Lee B., Nadon C.
    BMC Genomics 11:120-120(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 08-5578Imported.

Entry informationi

Entry nameiD2NWV8_LISM1
AccessioniPrimary (citable) accession number: D2NWV8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: February 4, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.