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D2NWC3

- D2NWC3_LISM1

UniProt

D2NWC3 - D2NWC3_LISM1

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Protein
Elongation factor Tu
Gene
tuf, LM5578_0207
Organism
Listeria monocytogenes serotype 1/2a (strain 08-5578)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciLMON653938:GJ8G-207-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:LM5578_0207Imported
    OrganismiListeria monocytogenes serotype 1/2a (strain 08-5578)Imported
    Taxonomic identifieri653938 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
    ProteomesiUP000001900: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiD2NWC3.

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD2NWC3.
    SMRiD2NWC3. Positions 2-393.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D2NWC3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKFDRSK PHVNIGTIGH VDHGKTTLTA AITTVLAKKG YADAQAYDQI    50
    DGAPEERERG ITISTAHVEY QTDSRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVVSAAD GPMPQTREHI LLSRQVGVPY IVVFMNKCDM VDDEELLELV 150
    EMEIRDLLTE YEFPGDDIPV IKGSALKALQ GEADWEAKID ELMEAVDSYI 200
    PTPERDTDKP FMMPVEDVFS ITGRGTVATG RVERGQVKVG DEVEVIGIEE 250
    ESKKVVVTGV EMFRKLLDYA EAGDNIGALL RGVAREDIQR GQVLAKPGSI 300
    TPHTNFKAET YVLTKEEGGR HTPFFNNYRP QFYFRTTDVT GIVTLPEGTE 350
    MVMPGDNIEL AVELIAPIAI EDGTKFSIRE GGRTVGAGVV SNISK 395
    Length:395
    Mass (Da):43,342
    Last modified:March 2, 2010 - v1
    Checksum:i93979D3141C00862
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001602 Genomic DNA. Translation: ADB66964.1.
    RefSeqiYP_003412326.1. NC_013766.1.

    Genome annotation databases

    EnsemblBacteriaiADB66964; ADB66964; LM5578_0207.
    GeneIDi8747200.
    KEGGilmn:LM5578_0207.
    PATRICi35274824. VBILisMon159512_0207.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001602 Genomic DNA. Translation: ADB66964.1 .
    RefSeqi YP_003412326.1. NC_013766.1.

    3D structure databases

    ProteinModelPortali D2NWC3.
    SMRi D2NWC3. Positions 2-393.
    ModBasei Search...

    Proteomic databases

    PRIDEi D2NWC3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADB66964 ; ADB66964 ; LM5578_0207 .
    GeneIDi 8747200.
    KEGGi lmn:LM5578_0207.
    PATRICi 35274824. VBILisMon159512_0207.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.

    Enzyme and pathway databases

    BioCyci LMON653938:GJ8G-207-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-throughput genome sequencing of two Listeria monocytogenes clinical isolates during a large foodborne outbreak."
      Gilmour M.W., Graham M., Van Domselaar G., Tyler S., Kent H., Trout-Yakel K.M., Larios O., Allen V., Lee B., Nadon C.
      BMC Genomics 11:120-120(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 08-5578Imported.

    Entry informationi

    Entry nameiD2NWC3_LISM1
    AccessioniPrimary (citable) accession number: D2NWC3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 2, 2010
    Last sequence update: March 2, 2010
    Last modified: June 11, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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