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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Listeria monocytogenes serotype 1/2a (strain 08-5578)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei60 – 601UniRule annotation

GO - Molecular functioni

  1. methylglyoxal synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. methylglyoxal biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciLMON653938:GJ8G-2137-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotationSAAS annotation (EC:4.2.3.3UniRule annotationSAAS annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotationImported
Ordered Locus Names:LM5578_2107Imported
OrganismiListeria monocytogenes serotype 1/2a (strain 08-5578)Imported
Taxonomic identifieri653938 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000001900 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD2NV89.
SMRiD2NV89. Positions 3-122.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000283729.
KOiK01734.

Family and domain databases

Gene3Di3.40.50.1380. 1 hit.
HAMAPiMF_00549. Methylglyoxal_synth.
InterProiIPR004363. Methylgl_synth.
IPR018148. Methylglyoxal_synth_AS.
IPR011607. MGS-like_dom.
[Graphical view]
PfamiPF02142. MGS. 1 hit.
[Graphical view]
PIRSFiPIRSF006614. Methylglyox_syn. 1 hit.
SMARTiSM00851. MGS. 1 hit.
[Graphical view]
SUPFAMiSSF52335. SSF52335. 1 hit.
TIGRFAMsiTIGR00160. MGSA. 1 hit.
PROSITEiPS01335. METHYLGLYOXAL_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2NV89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHIALIAHDE KKDLMVGFAT AYKHLLEPHQ LYATGTTGLR IIEATGLTVH
60 70 80 90 100
RFKSGPLGGD QQIGARISEN KMDLVIFLRD PLTAQPHEPD VTALIRLCDV
110 120 130
YEIPLATNIG TAEILIRGLG AGFLDWRDLR RNDE
Length:134
Mass (Da):14,883
Last modified:March 2, 2010 - v1
Checksum:iB569D4CEBC172193
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001602 Genomic DNA. Translation: ADB68854.1.
RefSeqiYP_003414216.1. NC_013766.2.

Genome annotation databases

EnsemblBacteriaiADB68854; ADB68854; LM5578_2107.
KEGGilmn:LM5578_2107.
PATRICi35278732. VBILisMon159512_2122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001602 Genomic DNA. Translation: ADB68854.1.
RefSeqiYP_003414216.1. NC_013766.2.

3D structure databases

ProteinModelPortaliD2NV89.
SMRiD2NV89. Positions 3-122.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADB68854; ADB68854; LM5578_2107.
KEGGilmn:LM5578_2107.
PATRICi35278732. VBILisMon159512_2122.

Phylogenomic databases

HOGENOMiHOG000283729.
KOiK01734.

Enzyme and pathway databases

BioCyciLMON653938:GJ8G-2137-MONOMER.

Family and domain databases

Gene3Di3.40.50.1380. 1 hit.
HAMAPiMF_00549. Methylglyoxal_synth.
InterProiIPR004363. Methylgl_synth.
IPR018148. Methylglyoxal_synth_AS.
IPR011607. MGS-like_dom.
[Graphical view]
PfamiPF02142. MGS. 1 hit.
[Graphical view]
PIRSFiPIRSF006614. Methylglyox_syn. 1 hit.
SMARTiSM00851. MGS. 1 hit.
[Graphical view]
SUPFAMiSSF52335. SSF52335. 1 hit.
TIGRFAMsiTIGR00160. MGSA. 1 hit.
PROSITEiPS01335. METHYLGLYOXAL_SYNTH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-throughput genome sequencing of two Listeria monocytogenes clinical isolates during a large foodborne outbreak."
    Gilmour M.W., Graham M., Van Domselaar G., Tyler S., Kent H., Trout-Yakel K.M., Larios O., Allen V., Lee B., Nadon C.
    BMC Genomics 11:120-120(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 08-5578Imported.

Entry informationi

Entry nameiD2NV89_LISM1
AccessioniPrimary (citable) accession number: D2NV89
Entry historyi
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: April 1, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.