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Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Rothia mucilaginosa (strain DY-18) (Stomatococcus mucilaginosus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCUniRule annotation
Gene namesi
Name:tatCUniRule annotation
Ordered Locus Names:RMDY18_10430
OrganismiRothia mucilaginosa (strain DY-18) (Stomatococcus mucilaginosus)
Taxonomic identifieri680646 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeRothia
Proteomesi
  • UP000001883 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 55HelicalUniRule annotationAdd BLAST21
Transmembranei87 – 107HelicalUniRule annotationAdd BLAST21
Transmembranei123 – 143HelicalUniRule annotationAdd BLAST21
Transmembranei173 – 193HelicalUniRule annotationAdd BLAST21
Transmembranei204 – 224HelicalUniRule annotationAdd BLAST21
Transmembranei228 – 248HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004128711 – 293Sec-independent protein translocase protein TatCAdd BLAST293

Interactioni

Subunit structurei

The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.UniRule annotation

Protein-protein interaction databases

STRINGi680646.RMDY18_10430.

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0805. LUCA.
HOGENOMiHOG000245380.
KOiK03118.
OMAiHLTEFRR.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.

Sequencei

Sequence statusi: Complete.

D2NT99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPDQDVRN RKINPEARME LKEHLREFRD RLIKAAIATI IAAIIGTVFL
60 70 80 90 100
YQPFIEMISA PLQQINIETG RRANLNYGSV ASPFDQLLKV GMYIGLVIAS
110 120 130 140 150
PVWLYQALRF LLPALHTKEK KYLFGFLTAS IFAFACGVAI SYFTLPGVVY
160 170 180 190 200
ALLKFTPVNE SNYIDAGVYI SFILKFVVTF SCAFIIPVIL VGINMLGLIR
210 220 230 240 250
GKTILKSWRW VVVLVAVIAA LTAPGSDIMM MFVLMAPLLI FFFAAIGICM
260 270 280 290
INDKRRDRKL AKLAQGSDEA SLNTATSSED LAKMGYFEEE KTS
Length:293
Mass (Da):32,656
Last modified:March 2, 2010 - v1
Checksum:iEB2483CFBF583D89
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP011540 Genomic DNA. Translation: BAI64875.1.
RefSeqiWP_012903535.1. NC_013715.1.

Genome annotation databases

EnsemblBacteriaiBAI64875; BAI64875; RMDY18_10430.
GeneIDi25055890.
KEGGirmu:RMDY18_10430.
PATRICi35272719. VBIRotMuc152186_0902.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP011540 Genomic DNA. Translation: BAI64875.1.
RefSeqiWP_012903535.1. NC_013715.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi680646.RMDY18_10430.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAI64875; BAI64875; RMDY18_10430.
GeneIDi25055890.
KEGGirmu:RMDY18_10430.
PATRICi35272719. VBIRotMuc152186_0902.

Phylogenomic databases

eggNOGiCOG0805. LUCA.
HOGENOMiHOG000245380.
KOiK03118.
OMAiHLTEFRR.

Family and domain databases

HAMAPiMF_00902. TatC. 1 hit.
InterProiIPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTATC_ROTMD
AccessioniPrimary (citable) accession number: D2NT99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: March 2, 2010
Last modified: November 2, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.