Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

D2NRR5 (D2NRR5_ROTMD) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase A HAMAP-Rule MF_00171

EC=5.4.99.12 HAMAP-Rule MF_00171
Alternative name(s):
tRNA pseudouridine(38-40) synthase HAMAP-Rule MF_00171
tRNA pseudouridylate synthase I HAMAP-Rule MF_00171
tRNA-uridine isomerase I HAMAP-Rule MF_00171
Gene names
Name:truA HAMAP-Rule MF_00171
Ordered Locus Names:RMDY18_05090 EMBL BAI64341.1
OrganismRothia mucilaginosa (strain DY-18) (Stomatococcus mucilaginosus) [Complete proteome] [HAMAP]
Taxonomic identifier680646 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeRothia

Protein attributes

Sequence length348 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs By similarity. HAMAP-Rule MF_00171 SAAS SAAS020097

Catalytic activity

tRNA uridine(38-40) = tRNA pseudouridine(38-40). HAMAP-Rule MF_00171 RuleBase RU003792 SAAS SAAS020097

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00171

Sequence similarities

Belongs to the tRNA pseudouridine synthase TruA family. HAMAP-Rule MF_00171 RuleBase RU003792

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site961Nucleophile By similarity HAMAP-Rule MF_00171
Binding site1871Substrate By similarity HAMAP-Rule MF_00171

Sequences

Sequence LengthMass (Da)Tools
D2NRR5 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: AD367ED3C0F33A0D

FASTA34838,696
        10         20         30         40         50         60 
MELFLRAPSL QEPCQCFRTL SPLKGTPMQN ATALENHEEQ LFIATHRVRI DCAYDGSLFS 

        70         80         90        100        110        120 
GWAAQPNLVT VQGVIENALE LILRAPHRVV VAGRTDAGVH AEAQTLHCDL SDEDWTRLQG 

       130        140        150        160        170        180 
RTGEDDPTAA LGRRLTGALQ RCLYDAEEQL NLPKNVRGIL QGAIQIHRVA EVPFDFDARF 

       190        200        210        220        230        240 
SATGRRYVYR IADGAADGLN PLHRTYTWAV PEHLDCADLN ESAQQLLGLR DFLSFCKPRE 

       250        260        270        280        290        300 
GATTIRELRE LSFTRTESAL IEVCVVADAF CHHMVRSLVG ALVLYGTGKR DAAWLRERIE 

       310        320        330        340 
NPGREASLTL APPHALALAE IYYPAPELYG EQAERARAKR EDDEAQSA 

« Hide

References

[1]"Complete genome sequence of Rothia mucilaginosa DJ."
Yamane K., Nambu T., Mashimo C., Sugimori C., Yamanaka T., Leung K., Fukushima H.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DY-18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP011540 Genomic DNA. Translation: BAI64341.1.
RefSeqYP_003362161.1. NC_013715.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAI64341; BAI64341; RMDY18_05090.
GeneID8693518.
KEGGrmu:RMDY18_05090.
PATRIC35271763. VBIRotMuc152186_0437.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000248674.
KOK06173.
OMACRPREGA.
OrthoDBEOG6Z9B4R.

Enzyme and pathway databases

BioCycRMUC680646:GH63-505-MONOMER.

Family and domain databases

Gene3D3.30.70.580. 2 hits.
3.30.70.660. 1 hit.
HAMAPMF_00171. TruA.
InterProIPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view]
PANTHERPTHR11142. PTHR11142. 1 hit.
PfamPF01416. PseudoU_synth_1. 2 hits.
[Graphical view]
SUPFAMSSF55120. SSF55120. 2 hits.
TIGRFAMsTIGR00071. hisT_truA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD2NRR5_ROTMD
AccessionPrimary (citable) accession number: D2NRR5
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: June 11, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)