Skip Header

Contribute Send feedback
Read comments (?) or add your own

D2NQQ3 (D2NQQ3_ROTMD) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP-Rule MF_00209
EC=3.6.1.1 HAMAP-Rule MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP-Rule MF_00209
Gene names
Name:ppa HAMAP-Rule MF_00209
Ordered Locus Names:RMDY18_01470
OrganismRothia mucilaginosa (strain DY-18) (Stomatococcus mucilaginosus) [Complete proteome] [HAMAP]
Taxonomic identifier680646 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Rothia ›

Protein attributes

Sequence length161 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP-Rule MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP-Rule MF_00209

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP-Rule MF_00209

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding521Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding571Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding571Magnesium 2 By similarity HAMAP-Rule MF_00209
Metal binding891Magnesium 1 By similarity HAMAP-Rule MF_00209

Sequences

Sequence LengthMass (Da)Tools
D2NQQ3 [UniParc].

Last modified March 2, 2010. Version 1.
Checksum: 231E3717DF2BED09

FASTA16118,202
        10         20         30         40         50         60 
MELDVTIEIP RGSRVKYEVD HETGRLRLDR VLFTSMQYPT AYGYFENTLG EDGDPLDAML 

        70         80         90        100        110        120 
ILDVDVVPGV LVESRPIAVF NMTDEAGGDA KVLCVPTDKR YDHIKSLADV PEQLKAEIQH 

       130        140        150        160 
FFERYKDLEP GKWVKGEGWE DLAAAEKMVQ EAIDRFAAEG H

« Hide

References

[1]"Complete genome sequence of Rothia mucilaginosa DJ."
Yamane K., Nambu T., Mashimo C., Sugimori C., Yamanaka T., Leung K., Fukushima H.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DY-18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP011540 Genomic DNA. Translation: BAI63979.1.
RefSeqYP_003361799.1. NC_013715.1.

3D structure databases

ModBaseSearch...

Proteomic databases

PRIDED2NQQ3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAI63979; BAI63979; RMDY18_01470.
GeneID8693169.
KEGGrmu:RMDY18_01470.
PATRIC35271115. VBIRotMuc152186_0125.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000236473.
KOK01507.
OMAHETGRVY.

Enzyme and pathway databases

BioCycRMUC680646:GH63-145-MONOMER.

Family and domain databases

Gene3D3.90.80.10. 1 hit.
HAMAPMF_00209. Inorganic_PPase.
InterProIPR008162. Pyrophosphatase.
[Graphical view]
PANTHERPTHR10286. PTHR10286. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2NQQ3_ROTMD
AccessionPrimary (citable) accession number: D2NQQ3
Entry history
Integrated into UniProtKB/TrEMBL: March 2, 2010
Last sequence update: March 2, 2010
Last modified: May 29, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info