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Protein
Submitted name:

Androgen receptor variant 5,6,7es

Gene

AR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi562 – 637Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Androgen receptor variant 5,6,7esImported
Gene namesi
Name:ARImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiD2KF13.
PeptideAtlasiD2KF13.

Expressioni

Gene expression databases

BgeeiENSG00000169083.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini562 – 637Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili54 – 83Sequence analysisAdd BLAST30

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR001103. Andrgn_rcpt.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF02166. Androgen_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00521. ANDROGENR.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D2KF13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV REVIQNPGPR HPEAASAAPP
60 70 80 90 100
GASLLLLQQQ QQQQQQQQQQ QQQQQQQQQQ QETSPRQQQQ QQGEDGSPQA
110 120 130 140 150
HRRGPTGYLV LDEEQQPSQP QSALECHPER GCVPEPGAAV AASKGLPQQL
160 170 180 190 200
PAPPDEDDSA APSTLSLLGP TFPGLSSCSA DLKDILSEAS TMQLLQQQQQ
210 220 230 240 250
EAVSEGSSSG RAREASGAPT SSKDNYLGGT STISDNAKEL CKAVSVSMGL
260 270 280 290 300
GVEALEHLSP GEQLRGDCMY APLLGVPPAV RPTPCAPLAE CKGSLLDDSA
310 320 330 340 350
GKSTEDTAEY SPFKGGYTKG LEGESLGCSG SAAAGSSGTL ELPSTLSLYK
360 370 380 390 400
SGALDEAAAY QSRDYYNFPL ALAGPPPPPP PPHPHARIKL ENPLDYGSAW
410 420 430 440 450
AAAAAQCRYG DLASLHGAGA AGPGSGSPSA AASSSWHTLF TAEEGQLYGP
460 470 480 490 500
CGGGGGGGGG GGGGGGGGGG GGGGGGGGEA GAVAPYGYTR PPQGLAGQES
510 520 530 540 550
DFTAPDVWYP GGMVSRVPYP SPTCVKSEMG PWMDSYSGPY GDMRLETARD
560 570 580 590 600
HVLPIDYYFP PQKTCLICGD EASGCHYGAL TCGSCKVFFK RAAEGKQKYL
610 620 630 640 650
CASRNDCTID KFRRKNCPSC RLRKCYEAGM TLGARKLKKL GNLKLQEEGE
660 670 680 690 700
ASSTTSPTEE TTQKLTVSHI EGYECQPIFL NVLEAIEPGV VCAGHDNNQP
710 720 730
DSFAALLSSL NELGERQLVH VVKWAKALPD CERAASVHF
Length:739
Mass (Da):77,372
Last modified:February 9, 2010 - v1
Checksum:i4495C9F9D3C860DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU208210 mRNA. Translation: ACZ81436.1.
UniGeneiHs.76704.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD2KF13_HUMAN
AccessioniPrimary (citable) accession number: D2KF13
Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: July 5, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.