SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D2IYK3

- D2IYK3_HUMAN

UniProt

D2IYK3 - D2IYK3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

POU class 5 homeobox 1 transcript variant 1

Gene
POU5F1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
POU class 5 homeobox 1 transcript variant 1Imported
Submitted name:
POU domain class 5 transcription factor 1 isoform 1Imported
Submitted name:
POU domain transcription factor OCT4Imported
Gene namesi
Name:POU5F1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Nucleus By similarity UniRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotations

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33545.

Family & Domainsi

Sequence similaritiesi

Contains POU-specific domain.SAAS annotations
Contains homeobox DNA-binding domain.SAAS annotations

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotationsImported

Phylogenomic databases

KOiK09367.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR015585. POU_dom_5.
IPR000327. POU_specific.
[Graphical view]
PANTHERiPTHR11636:SF15. PTHR11636:SF15. 1 hit.
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2IYK3-1 [UniParc]FASTAAdd to Basket

« Hide

MAGHLASDFA FSPPPGGGGD GPGGPEPGWV DPRTWLSFQG PPGGPGIGPG    50
VGPGSEVWGI PPCPPPYEFC GGMAYCGPQV GVGLVPQGGL ETSQPEGEAG 100
VGVESNSDGA SPEPCTVTPG AVKLEKEKLE QNPEESQDIK ALQKELEQFA 150
KLLKQKRITL GYTQADVGLT LGVLFGKVFS QTTICRFEAL QLSFKNMCKL 200
RPLLQKWVEE ADNNENLQEI CKAETLVQAR KRKRTSIENR VRGNLENLFL 250
QCPKPTLQQI SHIAQQLGLE KDVVRVWFCN RRQKGKRSSS DYAQREDFEA 300
AGSPFSGGPV SFPLAPGPHF GTPGYGSPHF TALYSSVPFP EGEAFPPVSV 350
TTLGSPMHSN 360
Length:360
Mass (Da):38,571
Last modified:February 9, 2010 - v1
Checksum:i934C58DAEA0C535B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GQ472773 Genomic DNA. Translation: ACZ95699.1.
GU480808 mRNA. Translation: ADE48539.1.
GU480811 mRNA. Translation: ADE48541.1.
GU480812 mRNA. Translation: ADE48542.1.
GU480816 mRNA. Translation: ADE48545.1.
GU480818 mRNA. Translation: ADE48547.1.
GU480824 mRNA. Translation: ADE48553.1.
GU480828 mRNA. Translation: ADE48557.1.
GU480830 mRNA. Translation: ADE48559.1.
HQ122660 mRNA. Translation: ADW77314.1.
HQ122662 mRNA. Translation: ADW77316.1.
HQ122664 mRNA. Translation: ADW77318.1.
HQ122667 mRNA. Translation: ADW77320.1.
HQ122668 mRNA. Translation: ADW77321.1.
HQ122669 mRNA. Translation: ADW77322.1.
HQ122670 mRNA. Translation: ADW77323.1.
HQ122672 mRNA. Translation: ADW77324.1.
HQ122673 mRNA. Translation: ADW77325.1.
HQ122674 mRNA. Translation: ADW77326.1.
HQ122675 mRNA. Translation: ADW77327.1.
KC312698 Genomic DNA. Translation: AGG40970.1.
RefSeqiNP_002692.2. NM_002701.5.
UniGeneiHs.249184.

Genome annotation databases

GeneIDi5460.
KEGGihsa:5460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
GQ472773 Genomic DNA. Translation: ACZ95699.1 .
GU480808 mRNA. Translation: ADE48539.1 .
GU480811 mRNA. Translation: ADE48541.1 .
GU480812 mRNA. Translation: ADE48542.1 .
GU480816 mRNA. Translation: ADE48545.1 .
GU480818 mRNA. Translation: ADE48547.1 .
GU480824 mRNA. Translation: ADE48553.1 .
GU480828 mRNA. Translation: ADE48557.1 .
GU480830 mRNA. Translation: ADE48559.1 .
HQ122660 mRNA. Translation: ADW77314.1 .
HQ122662 mRNA. Translation: ADW77316.1 .
HQ122664 mRNA. Translation: ADW77318.1 .
HQ122667 mRNA. Translation: ADW77320.1 .
HQ122668 mRNA. Translation: ADW77321.1 .
HQ122669 mRNA. Translation: ADW77322.1 .
HQ122670 mRNA. Translation: ADW77323.1 .
HQ122672 mRNA. Translation: ADW77324.1 .
HQ122673 mRNA. Translation: ADW77325.1 .
HQ122674 mRNA. Translation: ADW77326.1 .
HQ122675 mRNA. Translation: ADW77327.1 .
KC312698 Genomic DNA. Translation: AGG40970.1 .
RefSeqi NP_002692.2. NM_002701.5.
UniGenei Hs.249184.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 5460.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5460.
KEGGi hsa:5460.

Organism-specific databases

CTDi 5460.
PharmGKBi PA33545.

Phylogenomic databases

KOi K09367.

Miscellaneous databases

GenomeRNAii 5460.
NextBioi 21135.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR015585. POU_dom_5.
IPR000327. POU_specific.
[Graphical view ]
PANTHERi PTHR11636:SF15. PTHR11636:SF15. 1 hit.
Pfami PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view ]
PRINTSi PR00028. POUDOMAIN.
SMARTi SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparison of MHC class I risk haplotypes in Thai and Caucasian psoriatics shows locus heterogeneity at PSORS1."
    Stuart P.E., Nair R.P., Hiremagalore R., Kullavanijaya P., Kullavanijaya P., Tejasvi T., Lim H.W., Voorhees J.J., Elder J.T.
    Tissue Antigens 76:387-397(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BloodImported.
  2. "Expression of OCT4 Pseudogenes in Human Somatic Tumors."
    Zhao S., Yuan Q., Liu S., Zhang Y., Liu H., Wang F., Liu K., Hao A.
    Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "Expression of OCT4 pseudogenes in two human somatic tumours: glioma and breast carcinoma."
    Zhao S., Yuan Q., Guo Y., Liu S., Zhang Y., Wang J., Liu H., Wang F., Liu K., Ling E.-A., Hao A.
    Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: SeminomaImported.
  4. "An In-Depth Characterization of the Major Psoriasis Susceptibility Locus Identifies Candidate Susceptibility Alleles within an HLA-C Enhancer Element."
    Clop A., Bertoni A., Spain S.L., Simpson M.A., Pullabhatla V., Tonda R., Hundhausen C., Di Meglio P., De Jong P., Hayday A.C., Nestle F.O., Barker J.N., Bell R.J., Capon F., Trembath R.C.
    PLoS ONE 8:E71690-E71690(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiD2IYK3_HUMAN
AccessioniPrimary (citable) accession number: D2IYK3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: July 9, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi