D2HF00 (D2HF00_AILME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSAMEP00000008410

Gene names

Name:	PDHX Ensembl ENSAMEP00000008410
ORF Names:	PANDA_009414 EMBL EFB24746.1

Organism

Ailuropoda melanoleuca (Giant panda) [Reference proteome]

Taxonomic identifier

9646 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Laurasiatheria › Carnivora › Caniformia › Ursidae › Ailuropoda

Protein attributes

Sequence length	501 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. Contains 1 lipoyl-binding domain. RuleBase RU000447

Ontologies

Keywords
Domain	Lipoyl RuleBase RU000447
Molecular function	Acyltransferase RuleBase RU003765 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	mitochondrion Inferred from electronic annotation. Source: Compara
Molecular_function	transferase activity, transferring acyl groups Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	501	1	EMBL EFB24746.1

Sequences

	Sequence		Length	Mass (Da)
	D2HF00 [UniParc]. Last modified February 9, 2010. Version 1. Checksum: C615B695C25FB653	FASTA	501	54,007
	10 20 30 40 50 60 MAASWRVGCD PRVLRYLLGF GGCRRLGLVK GASGWSFGRG ASWRWLHGTQ RLRADPIKIL 70 80 90 100 110 120 MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK 130 140 150 160 170 180 NIRLGSLIGL LVEEGEDWKH VEIPKDVGPP SPAAKPSVPC PPPEPQISPP VKKEHTLGKL 190 200 210 220 230 240 QFRLSPAARN ILEKHALDAS QGTATGPRGI FTKEDALKLV QLKDTGKITE SRPTPAPPTT 250 260 270 280 290 300 PTVPLPAQAI PTPPYPRPMI PPLSTPGQPN VPGTFTEIPA SNIRRVIAKR LTESKSTVPH 310 320 330 340 350 360 AYATADCDLG AVLKARQSLV RDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF 370 380 390 400 410 420 IDISVAVATD KGLITPIIKD AAAKGVQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL 430 440 450 460 470 480 GMFGIDEFTA VINPPQACIL AVGRFRPVLK LEQDEEGNAR LQPHQLITVT MSSDSRVVDD 490 500 ELATRFLENF KANLENPIRL A

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence and de novo assembly of the giant panda genome." Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J. , Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L., Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J., Wang J. Nature 463:311-317(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (SEP-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACTA01137118 Genomic DNA. No translation available. ACTA01145117 Genomic DNA. No translation available. GL192767 Genomic DNA. Translation: EFB24746.1.
RefSeq	XP_002920665.1. XM_002920619.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSAMET00000008762; ENSAMEP00000008410; ENSAMEG00000007973.
GeneID	100475970.
KEGG	aml:100475970.
Organism-specific databases
CTD	8050.
Phylogenomic databases
GeneTree	ENSGT00560000077144.
HOGENOM	HOG000281566.
KO	K13997.
OMA	VGFPGRR.
Family and domain databases
Gene3D	3.30.559.10. 1 hit. 4.10.320.10. 1 hit.
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR011053. Single_hybrid_motif. [Graphical view]
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 1 hit. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 1 hit. PS00189. LIPOYL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D2HF00_AILME

Accession

Primary (citable) accession number: D2HF00

Entry history

Integrated into UniProtKB/TrEMBL:	February 9, 2010
Last sequence update:	February 9, 2010
Last modified:	April 3, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)