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Protein
Submitted name:

Uncharacterized protein

Gene

LOC100481969

Organism
Ailuropoda melanoleuca (Giant panda)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. RNA polymerase II core promoter proximal region sequence-specific DNA binding Source: Ensembl
  2. sequence-specific DNA binding transcription factor activity Source: Ensembl

GO - Biological processi

  1. apoptotic process Source: Ensembl
  2. CD8-positive, alpha-beta T cell differentiation Source: Ensembl
  3. cell cycle arrest Source: Ensembl
  4. cellular response to interferon-beta Source: Ensembl
  5. cellular response to mechanical stimulus Source: Ensembl
  6. defense response to virus Source: Ensembl
  7. interferon-gamma-mediated signaling pathway Source: Ensembl
  8. negative regulation of regulatory T cell differentiation Source: Ensembl
  9. negative regulation of transcription, DNA-templated Source: Ensembl
  10. positive regulation of interferon-beta production Source: Ensembl
  11. positive regulation of interleukin-12 biosynthetic process Source: Ensembl
  12. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  13. regulation of CD8-positive, alpha-beta T cell proliferation Source: Ensembl
  14. regulation of MyD88-dependent toll-like receptor signaling pathway Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:LOC100481969Imported
ORF Names:PANDA_000726Imported
OrganismiAiluropoda melanoleuca (Giant panda)
Taxonomic identifieri9646 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeAiluropoda
ProteomesiUP000008912 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nuclear chromatin Source: Ensembl
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119093.
HOGENOMiHOG000037937.
InParanoidiD2GVH4.
KOiK09444.
OMAiCKEEPEV.
OrthoDBiEOG72ZCFD.
TreeFamiTF328512.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR017431. Interferon_reg_fac-1/2.
IPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00605. IRF. 1 hit.
[Graphical view]
PIRSFiPIRSF038196. IFN_RF1/2. 1 hit.
PRINTSiPR00267. INTFRNREGFCT.
SMARTiSM00348. IRF. 1 hit.
[Graphical view]
PROSITEiPS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D2GVH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPITRMRMRP WLEMQINSNQ IPGLIWINKE EMIFQIPWKH AAKHGWDINK
60 70 80 90 100
DACLFRSWAI HTGRYKAGEK EPDPKTWKAN FRCAMNSLPD IEEVKDQSRN
110 120 130 140 150
KGSSAVRVYR MLPPLTKNQR KERKSKSSRD AKSKAKRKSC GDSSPDTFSD
160 170 180 190 200
GLSSSTLPDD HSSYTAQGYV GQDLEVERDL TPALSPCAVT STLPDWRIPV
210 220 230 240 250
EIVPDSTSDL YNFQVSPMPS TSEATTDEDE EGKLTEDIMK LLEQTGWQPT
260 270 280 290 300
NVDGKGYLLN EPGAQPTSLY GDFSCKEEPE VDSPGGYIGL ISSDLKNMDT
310 320
SWLDSLLPPV RLPSIQAIPC AP
Length:322
Mass (Da):36,083
Last modified:February 9, 2010 - v1
Checksum:i5B08905637ACC6A4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei322 – 3221Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACTA01008157 Genomic DNA. No translation available.
GL192350 Genomic DNA. Translation: EFB24253.1.
RefSeqiXP_002912943.1. XM_002912897.2.

Genome annotation databases

EnsembliENSAMET00000019449; ENSAMEP00000018700; ENSAMEG00000017694.
GeneIDi100481969.
KEGGiaml:100481969.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACTA01008157 Genomic DNA. No translation available.
GL192350 Genomic DNA. Translation: EFB24253.1.
RefSeqiXP_002912943.1. XM_002912897.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSAMET00000019449; ENSAMEP00000018700; ENSAMEG00000017694.
GeneIDi100481969.
KEGGiaml:100481969.

Organism-specific databases

CTDi3659.

Phylogenomic databases

GeneTreeiENSGT00760000119093.
HOGENOMiHOG000037937.
InParanoidiD2GVH4.
KOiK09444.
OMAiCKEEPEV.
OrthoDBiEOG72ZCFD.
TreeFamiTF328512.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR017431. Interferon_reg_fac-1/2.
IPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00605. IRF. 1 hit.
[Graphical view]
PIRSFiPIRSF038196. IFN_RF1/2. 1 hit.
PRINTSiPR00267. INTFRNREGFCT.
SMARTiSM00348. IRF. 1 hit.
[Graphical view]
PROSITEiPS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence and de novo assembly of the giant panda genome."
    Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.
    , Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L., Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J., Wang J.
    Nature 463:311-317(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiD2GVH4_AILME
AccessioniPrimary (citable) accession number: D2GVH4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: April 29, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.