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Protein

Conotoxin Pu11.2

Gene
N/A
Organism
Conus pulicarius (Flea-bite cone)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionToxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Pu11.2
OrganismiConus pulicarius (Flea-bite cone)
Taxonomic identifieri93154 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
PropeptideiPRO_000039215820 – 42Sequence analysisAdd BLAST23
PeptideiPRO_000039215943 – 81Conotoxin Pu11.2Add BLAST39

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi46 ↔ 60By similarity
Disulfide bondi53 ↔ 65By similarity
Disulfide bondi59 ↔ 74By similarity
Disulfide bondi64 ↔ 81By similarity

Keywords - PTMi

Cleavage on pair of basic residues, Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.

Structurei

3D structure databases

SMRiD2DGD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The cysteine framework is XI (C-C-CC-CC-C-C).

Sequence similaritiesi

Belongs to the conotoxin I3 superfamily.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR004214. Conotoxin.
PfamiView protein in Pfam
PF02950. Conotoxin. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D2DGD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLVLAIVLI LMLLSLSTGA ETSDNSASSS ATALRDRLLG RKVRTCQGMG
60 70 80
ESCSSNYDCC GSLCCAGASL FNGCVMGFVA C
Length:81
Mass (Da):8,335
Last modified:February 9, 2010 - v1
Checksum:i416E6810EBE964FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ531698 mRNA. Translation: ACU30044.1.

Similar proteinsi

Entry informationi

Entry nameiCI3B2_CONPL
AccessioniPrimary (citable) accession number: D2DGD7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 2, 2010
Last sequence update: February 9, 2010
Last modified: November 22, 2017
This is version 15 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families