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Protein

Conotoxin Ca11b

Gene
N/A
Organism
Conus caracteristicus (Characteristic cone)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionToxin

Names & Taxonomyi

Protein namesi
Recommended name:
Conotoxin Ca11b
Alternative name(s):
Ca11.2
OrganismiConus caracteristicus (Characteristic cone)
Taxonomic identifieri89440 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
PropeptideiPRO_000039215220 – 421 PublicationAdd BLAST23
PeptideiPRO_000039215343 – 76Conotoxin Ca11bAdd BLAST34

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi46 ↔ 60By similarity
Disulfide bondi53 ↔ 65By similarity
Disulfide bondi59 ↔ 69By similarity
Disulfide bondi64 ↔ 76By similarity

Keywords - PTMi

Disulfide bond

Expressioni

Tissue specificityi

Expressed by the venom duct.

Structurei

3D structure databases

ProteinModelPortaliD2DGD4.
SMRiD2DGD4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

The cysteine framework is XI (C-C-CC-CC-C-C).

Sequence similaritiesi

Belongs to the conotoxin I3 superfamily.Curated

Keywords - Domaini

Signal

Family and domain databases

PROSITEiView protein in PROSITE
PS60019. I_CONOTOXIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D2DGD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLVLAIVVI LMLLSLSTGA EMSDNHASMS ANALRDRLLG PKALLCGGTH
60 70
ARCNRDNDCC GSLCCFGTCI SAFVPC
Length:76
Mass (Da):7,975
Last modified:February 9, 2010 - v1
Checksum:i59889A45C148430E
GO

Mass spectrometryi

Molecular mass is 3504.3 Da from positions 43 - 76. Determined by ESI. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ531695 mRNA. Translation: ACU30041.1.

Similar proteinsi

Entry informationi

Entry nameiCI3BB_CONCB
AccessioniPrimary (citable) accession number: D2DGD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 2, 2010
Last sequence update: February 9, 2010
Last modified: November 22, 2017
This is version 19 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programAnimal Toxin Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families