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D2D3P4

- D2D3P4_CHICK

UniProt

D2D3P4 - D2D3P4_CHICK

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Protein
Submitted name:

Rab27a

Gene

Rab27a

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. GDP binding Source: Ensembl
  2. GTPase activity Source: Ensembl
  3. GTP binding Source: UniProtKB-KW

GO - Biological processi

  1. antigen processing and presentation Source: Ensembl
  2. blood coagulation Source: Ensembl
  3. cytotoxic T cell degranulation Source: Ensembl
  4. melanocyte differentiation Source: Ensembl
  5. melanosome transport Source: Ensembl
  6. multivesicular body sorting pathway Source: Ensembl
  7. natural killer cell degranulation Source: Ensembl
  8. positive regulation of exocytosis Source: Ensembl
  9. protein targeting Source: Ensembl
  10. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Rab27aImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:Rab27aImported
Synonyms:RAB27AImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome 10

Subcellular locationi

GO - Cellular componenti

  1. dendrite Source: Ensembl
  2. exocytic vesicle Source: Ensembl
  3. extracellular vesicular exosome Source: Ensembl
  4. Golgi apparatus Source: Ensembl
  5. lysosome Source: Ensembl
  6. melanosome Source: Ensembl
  7. multivesicular body membrane Source: Ensembl
  8. photoreceptor outer segment Source: Ensembl
  9. secretory granule Source: Ensembl
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliD2D3P4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119310.
HOGENOMiHOG000233968.
InParanoidiD2D3P4.
KOiK07885.
OMAiDQRAVKE.
OrthoDBiEOG7FFMSC.
PhylomeDBiD2D3P4.
TreeFamiTF312895.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
PRINTSiPR00449. RASTRNSFRMNG.
SMARTiSM00175. RAB. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

D2D3P4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDGDYDYLI KFLALGDSGV GKTSLLYQYT DGKFNSKFIT TVGIDFREKR
60 70 80 90 100
VVYRPNGPDG VGGRGQRIHL QLWDTAGQER FRSLTTAFFR DAMGFLLLFD
110 120 130 140 150
LTNEQSFLNV RNWISQLQMH AYCENPDIVL CGNKSDLEDQ RMVKEEEAKE
160 170 180 190 200
LAEKYGIPYF ETSAANGNNV SKAIDTLLDL IMKRMERCVD KSWIPEGVVR
210 220
SNGHSSTEQL SEEQEKGKCG C
Length:221
Mass (Da):25,066
Last modified:February 9, 2010 - v1
Checksum:iCEED02401D349B04
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AADN03006119 Genomic DNA. No translation available.
FJ449551 mRNA. Translation: ACT15614.1.
RefSeqiNP_001162176.1. NM_001168705.1.
UniGeneiGga.7113.

Genome annotation databases

EnsembliENSGALT00000007059; ENSGALP00000007047; ENSGALG00000004435.
GeneIDi415410.
KEGGigga:415410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AADN03006119 Genomic DNA. No translation available.
FJ449551 mRNA. Translation: ACT15614.1 .
RefSeqi NP_001162176.1. NM_001168705.1.
UniGenei Gga.7113.

3D structure databases

ProteinModelPortali D2D3P4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000007059 ; ENSGALP00000007047 ; ENSGALG00000004435 .
GeneIDi 415410.
KEGGi gga:415410.

Organism-specific databases

CTDi 5873.

Phylogenomic databases

GeneTreei ENSGT00760000119310.
HOGENOMi HOG000233968.
InParanoidi D2D3P4.
KOi K07885.
OMAi DQRAVKE.
OrthoDBi EOG7FFMSC.
PhylomeDBi D2D3P4.
TreeFami TF312895.

Miscellaneous databases

NextBioi 20819024.
PROi D2D3P4.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
InterProi IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003579. Small_GTPase_Rab_type.
[Graphical view ]
Pfami PF00071. Ras. 1 hit.
[Graphical view ]
PRINTSi PR00449. RASTRNSFRMNG.
SMARTi SM00175. RAB. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00231. small_GTP. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
    International Chicken Genome Sequencing Consortium
    Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A.
    , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K.
    Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Red jungle fowlImported.
  2. "Population genetics and molecular evolution of plumage genes: Rab27a."
    Vaez M., Burke T.
    Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Red jungle fowlImported.

Entry informationi

Entry nameiD2D3P4_CHICK
AccessioniPrimary (citable) accession number: D2D3P4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3