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D2D3P4

- D2D3P4_CHICK

UniProt

D2D3P4 - D2D3P4_CHICK

Protein
Submitted name:

Rab27a

Gene

Rab27a

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (09 Feb 2010)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. GDP binding Source: Ensembl
    2. GTPase activity Source: Ensembl
    3. GTP binding Source: UniProtKB-KW

    GO - Biological processi

    1. blood coagulation Source: Ensembl
    2. cytotoxic T cell degranulation Source: Ensembl
    3. melanocyte differentiation Source: Ensembl
    4. melanosome transport Source: Ensembl
    5. multivesicular body sorting pathway Source: Ensembl
    6. natural killer cell degranulation Source: Ensembl
    7. positive regulation of exocytosis Source: Ensembl
    8. protein targeting Source: Ensembl
    9. small GTPase mediated signal transduction Source: InterPro

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Rab27aImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:Rab27aImported
    Synonyms:RAB27AImported
    OrganismiGallus gallus (Chicken)Imported
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
    ProteomesiUP000000539: Chromosome 10

    Subcellular locationi

    GO - Cellular componenti

    1. dendrite Source: Ensembl
    2. exocytic vesicle Source: Ensembl
    3. Golgi apparatus Source: Ensembl
    4. lysosome Source: Ensembl
    5. melanosome Source: Ensembl
    6. multivesicular body membrane Source: Ensembl
    7. photoreceptor outer segment Source: Ensembl
    8. secretory granule Source: Ensembl

    Structurei

    3D structure databases

    ProteinModelPortaliD2D3P4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the small GTPase superfamily. Rab family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000114962.
    HOGENOMiHOG000233968.
    KOiK07885.
    OMAiDQRAVKE.
    OrthoDBiEOG7FFMSC.
    PhylomeDBiD2D3P4.
    TreeFamiTF312895.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003579. Small_GTPase_Rab_type.
    [Graphical view]
    PfamiPF00071. Ras. 1 hit.
    [Graphical view]
    PRINTSiPR00449. RASTRNSFRMNG.
    SMARTiSM00175. RAB. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00231. small_GTP. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D2D3P4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDGDYDYLI KFLALGDSGV GKTSLLYQYT DGKFNSKFIT TVGIDFREKR    50
    VVYRPNGPDG VGGRGQRIHL QLWDTAGQER FRSLTTAFFR DAMGFLLLFD 100
    LTNEQSFLNV RNWISQLQMH AYCENPDIVL CGNKSDLEDQ RMVKEEEAKE 150
    LAEKYGIPYF ETSAANGNNV SKAIDTLLDL IMKRMERCVD KSWIPEGVVR 200
    SNGHSSTEQL SEEQEKGKCG C 221
    Length:221
    Mass (Da):25,066
    Last modified:February 9, 2010 - v1
    Checksum:iCEED02401D349B04
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AADN03006119 Genomic DNA. No translation available.
    FJ449551 mRNA. Translation: ACT15614.1.
    RefSeqiNP_001162176.1. NM_001168705.1.
    UniGeneiGga.7113.

    Genome annotation databases

    EnsembliENSGALT00000007059; ENSGALP00000007047; ENSGALG00000004435.
    GeneIDi415410.
    KEGGigga:415410.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AADN03006119 Genomic DNA. No translation available.
    FJ449551 mRNA. Translation: ACT15614.1 .
    RefSeqi NP_001162176.1. NM_001168705.1.
    UniGenei Gga.7113.

    3D structure databases

    ProteinModelPortali D2D3P4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSGALT00000007059 ; ENSGALP00000007047 ; ENSGALG00000004435 .
    GeneIDi 415410.
    KEGGi gga:415410.

    Organism-specific databases

    CTDi 5873.

    Phylogenomic databases

    GeneTreei ENSGT00740000114962.
    HOGENOMi HOG000233968.
    KOi K07885.
    OMAi DQRAVKE.
    OrthoDBi EOG7FFMSC.
    PhylomeDBi D2D3P4.
    TreeFami TF312895.

    Miscellaneous databases

    NextBioi 20819024.
    PROi D2D3P4.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR003579. Small_GTPase_Rab_type.
    [Graphical view ]
    Pfami PF00071. Ras. 1 hit.
    [Graphical view ]
    PRINTSi PR00449. RASTRNSFRMNG.
    SMARTi SM00175. RAB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00231. small_GTP. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
      International Chicken Genome Sequencing Consortium
      Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A.
      , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K.
      Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Red jungle fowlImported.
    2. "Population genetics and molecular evolution of plumage genes: Rab27a."
      Vaez M., Burke T.
      Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Red jungle fowlImported.

    Entry informationi

    Entry nameiD2D3P4_CHICK
    AccessioniPrimary (citable) accession number: D2D3P4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 9, 2010
    Last sequence update: February 9, 2010
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3