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Protein

Multidrug resistance protein MdtG

Gene

mdtG

Organism
Dickeya dadantii (strain Ech586)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciDDAD590409:GHDW-1612-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Multidrug resistance protein MdtGUniRule annotation
Gene namesi
Name:mdtGUniRule annotation
Ordered Locus Names:Dd586_1568
OrganismiDickeya dadantii (strain Ech586)
Taxonomic identifieri590409 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeDickeya
Proteomesi
  • UP000001446 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalUniRule annotationAdd
BLAST
Transmembranei51 – 7121HelicalUniRule annotationAdd
BLAST
Transmembranei89 – 10921HelicalUniRule annotationAdd
BLAST
Transmembranei112 – 13221HelicalUniRule annotationAdd
BLAST
Transmembranei138 – 15821HelicalUniRule annotationAdd
BLAST
Transmembranei170 – 19021HelicalUniRule annotationAdd
BLAST
Transmembranei221 – 24121HelicalUniRule annotationAdd
BLAST
Transmembranei253 – 27321HelicalUniRule annotationAdd
BLAST
Transmembranei287 – 30721HelicalUniRule annotationAdd
BLAST
Transmembranei375 – 39521HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408Multidrug resistance protein MdtGPRO_0000414577Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi590409.Dd586_1568.

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFTQSNAD.
OrthoDBiEOG6VF34T.

Family and domain databases

HAMAPiMF_01528. MFS_MdtG.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2BX50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDTAPIDWK RNLYIAWLGC FFTGAAFSLV MPFLSLYVEQ LGIQGHEALN
60 70 80 90 100
LWSGVVFSIT FLFSAIASPF WGRLADRKGR KLMLLRSALG MAIVMALMGL
110 120 130 140 150
VQNIWQFLLL RAALGVLGGF VPNANALIAI QVPRNRSGWA LGTLSTGAVG
160 170 180 190 200
GALLGPLLGG YLADTFGLRP VFFITAVVLF ICFLVTFFFI RERIEPVREK
210 220 230 240 250
GMLSGRQVMV SLQNPHLVMS LFVTTLIIQV ATGSVAPILT LYVRELAGQT
260 270 280 290 300
DNLAFISGAI AAIPGVSALL SAPRLGKLGD KIGPERILVA MLILSVLLLI
310 320 330 340 350
PMAFVQSPWQ LAVLRFLLGA ADGALLPAVQ TLLIYHSSHQ VAGRIFSYNQ
360 370 380 390 400
SFRDVGNVTG PLLGASVSAS FGFRAVFLVT ASVVMINAFY SWLSLRRKSN

RELVSEAE
Length:408
Mass (Da):44,164
Last modified:February 9, 2010 - v1
Checksum:i8BD4048B56A158F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001836 Genomic DNA. Translation: ACZ76434.1.
RefSeqiWP_012884263.1. NC_013592.1.

Genome annotation databases

EnsemblBacteriaiACZ76434; ACZ76434; Dd586_1568.
KEGGiddc:Dd586_1568.
PATRICi32069839. VBIDicDad110536_1571.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001836 Genomic DNA. Translation: ACZ76434.1.
RefSeqiWP_012884263.1. NC_013592.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi590409.Dd586_1568.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACZ76434; ACZ76434; Dd586_1568.
KEGGiddc:Dd586_1568.
PATRICi32069839. VBIDicDad110536_1571.

Phylogenomic databases

eggNOGiENOG4105C6X. Bacteria.
ENOG410ZVCH. LUCA.
HOGENOMiHOG000066093.
KOiK08161.
OMAiFTQSNAD.
OrthoDBiEOG6VF34T.

Enzyme and pathway databases

BioCyciDDAD590409:GHDW-1612-MONOMER.

Family and domain databases

HAMAPiMF_01528. MFS_MdtG.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR023692. Mutidrug-R_MdtG.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ech586.

Entry informationi

Entry nameiMDTG_DICD5
AccessioniPrimary (citable) accession number: D2BX50
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 14, 2011
Last sequence update: February 9, 2010
Last modified: November 11, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.