ID   D2BS96_DICZ5            Unreviewed;       523 AA.
AC   D2BS96;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000256|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000256|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000256|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000256|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000256|HAMAP-Rule:MF_00212};
GN   OrderedLocusNames=Dd586_2803 {ECO:0000313|EMBL:ACZ77643.1};
OS   Dickeya zeae (strain Ech586) (Dickeya dadantii (strain Ech586)).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Dickeya; Dickeya parazeae.
OX   NCBI_TaxID=590409 {ECO:0000313|EMBL:ACZ77643.1, ECO:0000313|Proteomes:UP000001446};
RN   [1] {ECO:0000313|EMBL:ACZ77643.1, ECO:0000313|Proteomes:UP000001446}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ech586 {ECO:0000313|EMBL:ACZ77643.1,
RC   ECO:0000313|Proteomes:UP000001446};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Dickeya dadantii Ech586.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00001139, ECO:0000256|HAMAP-
CC         Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974, ECO:0000256|HAMAP-
CC         Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000256|ARBA:ARBA00005012, ECO:0000256|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000256|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP001836; ACZ77643.1; -; Genomic_DNA.
DR   RefSeq; WP_012885454.1; NC_013592.1.
DR   AlphaFoldDB; D2BS96; -.
DR   STRING; 590409.Dd586_2803; -.
DR   KEGG; ddc:Dd586_2803; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OrthoDB; 9763983at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001446; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   NCBIfam; TIGR01320; mal_quin_oxido; 1.
DR   PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|HAMAP-Rule:MF_00212};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|HAMAP-
KW   Rule:MF_00212};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002, ECO:0000256|HAMAP-
KW   Rule:MF_00212}; Signal {ECO:0000256|SAM:SignalP};
KW   Tricarboxylic acid cycle {ECO:0000256|HAMAP-Rule:MF_00212}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..523
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003028700"
SQ   SEQUENCE   523 AA;  57637 MW;  83630CEB92D3222A CRC64;
     MKKLLVTTLC LGTIGLAQPA MAEEQHAVDV VLIGGGVMSA TLGTYLQALE PNWTISMVER
     LDNVAQESSN GWNNAGTGHS AFMELNYTPE KADGSIDISK AVEISEAFEV SRQFWSYQIS
     HDVMKDPSSF INSVPHMSFV WGDENVNYLH KRYQALQHST LFRGMAFSDN PEQIKQWIPL
     VMEGRDSQQK VAATRMPIGT DVNYGEVTRQ LVNGLQQHST FNLKLNNEVR DIKRNPDKTW
     RVVVADLKNG GKESAINAKF VFIGAGGAAL QLLQKSGIPE ANNYGGFPVG GEFLVTDNPD
     IVKRHLAKVY GKASVGAPPM SVPHLDTRIF DGKPVLLFGP FATFSSKFLK NGSLWDLISS
     MNTSNVIPMM DVGIDNFDLV KYLIGQLMMN DDDRFAALKE YFPQAKPSDW RLAVAGQRVQ
     VIKKDKEQGG VLKLGTEIVS DKDGTIAALL GASPGASTAA PIMLSLLQTV FKDKVATPQW
     QTKLKEIIPS YGQKLEGNIE LTNTIRRYTS STLKLDYMEV KPE
//