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D2BR59

- D2BR59_LACLK

UniProt

D2BR59 - D2BR59_LACLK

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Protein

Glutamate decarboxylase

Gene

gadB

Organism
Lactococcus lactis subsp. lactis (strain KF147)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciLLAC684738:GI3F-1397-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadBImported
Ordered Locus Names:LLKF_1356Imported
OrganismiLactococcus lactis subsp. lactis (strain KF147)Imported
Taxonomic identifieri684738 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000001886: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiDEYALAH.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

D2BR59-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLYGKENRDE AEFLEPIFGS ESEQVDLPKY KLAQKSIEPR VAYQLVQDEM
60 70 80 90 100
LDEGNARLNL ATFCQTYMEP EALKLMSQTL EKNAIDKSEY PRTTEIENRC
110 120 130 140 150
VNMIADLWNA CEKEKFMGTS TIGSSEACML GGMAMKFSWR KRAEKLGLDI
160 170 180 190 200
NAKKPNLVIS SGYQVCWEKF CVYWDIEMRE VPMDKEHMSI NLDKVMDYVD
210 220 230 240 250
EYTIGVVGIM GITYTGRYDD IKALDNLIEE YNKQTDYKVY IHVDAASGGL
260 270 280 290 300
YAPFVEPELE WDFRLKNVIS INTSGHKYGL VYPGVGWVLW RDKKYLPEEL
310 320 330 340 350
IFKVSYLGGE LPTMAINFSH SASQLIGQYY NFVRYGFDGY KAIHERTHKV
360 370 380 390 400
AMFLAKEIEK TGMFEIMNDG SQLPIVCYKL KENSNRGWNL YDLADRLLMK
410 420 430 440 450
GWQVPAYPLP KNLENEIIQR LVIRADFGMN MAFNYVQDMQ EAIEALNKAH
460
ILYHEEPENK TYGFTH
Length:466
Mass (Da):53,942
Last modified:February 9, 2010 - v1
Checksum:i535E2CDE274354C4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001834 Genomic DNA. Translation: ADA65034.1.
RefSeqiYP_003353790.1. NC_013656.1.

Genome annotation databases

EnsemblBacteriaiADA65034; ADA65034; LLKF_1356.
GeneIDi8678778.
KEGGillk:LLKF_1356.
PATRICi32251206. VBILacLac141273_1375.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001834 Genomic DNA. Translation: ADA65034.1 .
RefSeqi YP_003353790.1. NC_013656.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADA65034 ; ADA65034 ; LLKF_1356 .
GeneIDi 8678778.
KEGGi llk:LLKF_1356.
PATRICi 32251206. VBILacLac141273_1375.

Phylogenomic databases

HOGENOMi HOG000070228.
KOi K01580.
OMAi DEYALAH.
OrthoDBi EOG6TFCPW.

Enzyme and pathway databases

BioCyci LLAC684738:GI3F-1397-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome-scale genotype-phenotype matching of two Lactococcus lactis isolates from plants identifies mechanisms of adaptation to the plant niche."
    Siezen R.J., Starrenburg M.J., Boekhorst J., Renckens B., Molenaar D., van Hylckama Vlieg J.E.
    Appl. Environ. Microbiol. 74:424-436(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KF147Imported.

Entry informationi

Entry nameiD2BR59_LACLK
AccessioniPrimary (citable) accession number: D2BR59
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3