Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

D2BKG6

- D2BKG6_LACLK

UniProt

D2BKG6 - D2BKG6_LACLK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Amidophosphoribosyltransferase

Gene

purF

Organism
Lactococcus lactis subsp. lactis (strain KF147)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391For GATase activityUniRule annotation

GO - Molecular functioni

  1. amidophosphoribosyltransferase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
  2. nucleoside metabolic process Source: InterPro
  3. purine nucleobase biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotationImported, Transferase

Keywords - Biological processi

Purine biosynthesisUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciLLAC684738:GI3F-1696-MONOMER.
UniPathwayiUPA00074; UER00124.

Names & Taxonomyi

Protein namesi
Recommended name:
AmidophosphoribosyltransferaseUniRule annotation (EC:2.4.2.14UniRule annotation)
Short name:
ATaseUniRule annotation
Alternative name(s):
Glutamine phosphoribosylpyrophosphate amidotransferaseUniRule annotation
Gene namesi
Name:purFImported
Ordered Locus Names:LLKF_1649Imported
OrganismiLactococcus lactis subsp. lactis (strain KF147)Imported
Taxonomic identifieri684738 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
ProteomesiUP000001886: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD2BKG6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000033688.
KOiK00764.
OMAiRIIDACE.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.40.50.2020. 1 hit.
3.60.20.10. 1 hit.
InterProiIPR005854. Amd_phspho_trans.
IPR017932. GATase_2_dom.
IPR029055. Ntn_hydrolases_N.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
PIRSFiPIRSF000485. Amd_phspho_trans. 1 hit.
SUPFAMiSSF53271. SSF53271. 1 hit.
SSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01134. purF. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2BKG6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFGKEQTLDL RVLGKNSSNE NSWWQQHPDD ERSHLNEECG LFGVWGHPDA
60 70 80 90 100
ARLTYFGLHA LQHRGQEGAG ILVNNNGKLN RHRGLGLVTE VFRDEKDLEE
110 120 130 140 150
LTGSSAIGHV RYATAGSANI NNIQPFQFEF HDGALGLAHN GNLTNAQSLR
160 170 180 190 200
CELEKSGAIF SSNSDTEILM HLIRRSHHPE FMGRVKEALN TVKGGFAYLI
210 220 230 240 250
MTENSIVAAL DPNGFRPLSI GKMSNGALVV ASETCAFDVV GATWIQDVQP
260 270 280 290 300
GEIIEINDVG IHVDQFTDST NMTICSMEYI YFARPDSNIA GVNVHTARKR
310 320 330 340 350
SGKILAQEAQ IDADIVIGVP NSSLSAASGY AEESGLPYEM GLIKNQYVAR
360 370 380 390 400
TFIQPTQELR EQGVRMKLSA VRGVVEGKRV IMVDDSIVRG TTSRRIVKLL
410 420 430 440 450
KDAGAAEVHV AIASPALKYP CFYGIDIQDR DELIAATHTT DEIRKAIGAD
460 470 480 490
SLTYLSQSGL VEAIGHDKLC LSYFDGEYPT PLYDYEADYL ESLAKNSVK
Length:499
Mass (Da):54,774
Last modified:February 9, 2010 - v1
Checksum:i8CBAA401909E7722
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001834 Genomic DNA. Translation: ADA65272.1.
RefSeqiYP_003354072.1. NC_013656.1.

Genome annotation databases

EnsemblBacteriaiADA65272; ADA65272; LLKF_1649.
GeneIDi8679077.
KEGGillk:LLKF_1649.
PATRICi32251797. VBILacLac141273_1666.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001834 Genomic DNA. Translation: ADA65272.1 .
RefSeqi YP_003354072.1. NC_013656.1.

3D structure databases

ProteinModelPortali D2BKG6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADA65272 ; ADA65272 ; LLKF_1649 .
GeneIDi 8679077.
KEGGi llk:LLKF_1649.
PATRICi 32251797. VBILacLac141273_1666.

Phylogenomic databases

HOGENOMi HOG000033688.
KOi K00764.
OMAi RIIDACE.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00124 .
BioCyci LLAC684738:GI3F-1696-MONOMER.

Family and domain databases

Gene3Di 3.40.50.2020. 1 hit.
3.60.20.10. 1 hit.
InterProi IPR005854. Amd_phspho_trans.
IPR017932. GATase_2_dom.
IPR029055. Ntn_hydrolases_N.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view ]
Pfami PF00156. Pribosyltran. 1 hit.
[Graphical view ]
PIRSFi PIRSF000485. Amd_phspho_trans. 1 hit.
SUPFAMi SSF53271. SSF53271. 1 hit.
SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01134. purF. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome-scale genotype-phenotype matching of two Lactococcus lactis isolates from plants identifies mechanisms of adaptation to the plant niche."
    Siezen R.J., Starrenburg M.J., Boekhorst J., Renckens B., Molenaar D., van Hylckama Vlieg J.E.
    Appl. Environ. Microbiol. 74:424-436(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KF147Imported.

Entry informationi

Entry nameiD2BKG6_LACLK
AccessioniPrimary (citable) accession number: D2BKG6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3