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D2BI46

- D2BI46_DEHMV

UniProt

D2BI46 - D2BI46_DEHMV

Protein

Elongation factor Tu

Gene

tuf

Organism
Dehalococcoides mccartyi (strain VS)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (09 Feb 2010)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciDSP311424:GJ8J-843-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:DhcVS_869Imported
    OrganismiDehalococcoides mccartyi (strain VS)Imported
    Taxonomic identifieri311424 [NCBI]
    Taxonomic lineageiBacteriaChloroflexiDehalococcoidiaDehalococcoidalesDehalococcoidaceaeDehalococcoides
    ProteomesiUP000002506: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD2BI46.
    SMRiD2BI46. Positions 2-400.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiSSYSISH.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D2BI46-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKQKFDRSK PHCNVGTIGH VDHGKTTLTA AITKTLSTKG WADFRAYDQI    50
    DNAPEEKARG LTIAISHIEY QTETRHYAHI DCPGHADYIK NMITGAAQMD 100
    GAILVVSAPD GPMPQTREHV LLIHQVEVPA VVVALNKCDM MDDEELLELV 150
    ELEVRELLTK NSFPGDEIPV VRVSAIKALE CGCGKRECEW CGRIWKLMDA 200
    VDSYIPIPPR PVDKPFLMKV EDVFSIKGRG TVATGRVERG VIKGGDEVDL 250
    VGLHHEPRKI VVTSLEMFHK ILDSAEPGDA VGLLLRGVER EDIERGMVLA 300
    KPGSIKPHVN AEAEVYVLSK DEGGRHTPFF NGYKPQFFFG TTDVTGEIHL 350
    PEGVEMVVPG DHVKMKISTI YPVAMEKGMR FAIREGGKTV GAGAISQVLA 400
    Length:400
    Mass (Da):43,944
    Last modified:February 9, 2010 - v1
    Checksum:i766975BAE37D1208
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001827 Genomic DNA. Translation: ACZ61996.1.
    RefSeqiWP_012882149.1. NC_013552.1.
    YP_003330324.1. NC_013552.1.

    Genome annotation databases

    EnsemblBacteriaiACZ61996; ACZ61996; DhcVS_869.
    GeneIDi8657801.
    KEGGidev:DhcVS_869.
    PATRICi32058640. VBIDehSp95780_0830.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001827 Genomic DNA. Translation: ACZ61996.1 .
    RefSeqi WP_012882149.1. NC_013552.1.
    YP_003330324.1. NC_013552.1.

    3D structure databases

    ProteinModelPortali D2BI46.
    SMRi D2BI46. Positions 2-400.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACZ61996 ; ACZ61996 ; DhcVS_869 .
    GeneIDi 8657801.
    KEGGi dev:DhcVS_869.
    PATRICi 32058640. VBIDehSp95780_0830.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi SSYSISH.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci DSP311424:GJ8J-843-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Localized plasticity in the streamlined genomes of vinyl chloride respiring Dehalococcoides."
      McMurdie P.J., Behrens S.F., Muller J.A., Goke J., Ritalahti K.M., Wagner R., Goltsman E., Lapidus A., Holmes S., Loffler F.E., Spormann A.M.
      PLoS Genet. 5:E1000714-E1000714(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: VSImported.

    Entry informationi

    Entry nameiD2BI46_DEHMV
    AccessioniPrimary (citable) accession number: D2BI46
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 9, 2010
    Last sequence update: February 9, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3