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D2BEG1 (D2BEG1_STRRD) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Sros_9380 EMBL ACZ91998.1
OrganismStreptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) [Complete proteome] [HAMAP] EMBL ACZ91998.1
Taxonomic identifier479432 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeStreptosporangiaceaeStreptosporangium

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain103 – 310208ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding137 – 19256ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2641Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2771Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2791Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D2BEG1 [UniParc].

Last modified February 9, 2010. Version 1.
Checksum: A400422C10F2CC96

FASTA31832,934
        10         20         30         40         50         60 
MSDLGYVLVL AGGLSYEREV SLRSGRRVSE VLRTAGIVVE TRDTDASLVP SILADPPDAV 

        70         80         90        100        110        120 
FVTLHGGAGE DGAIRSVLEL LSVPYVGAGP DACRVAFDKP TAKTVVRSVG LRTPDSVTLP 

       130        140        150        160        170        180 
KETFHDLGAS TVLTRIVERL GLPLFVKPSR GGSALGASIV RAAEDLPAAM VGCFAYGDTA 

       190        200        210        220        230        240 
LIERCIEGVE VAVSVVDLGG GPMALPPVEI VPDKGVYDYA ARYTAGHTEF FAPARLSPEA 

       250        260        270        280        290        300 
AAACAEMAVT AHTALGLRDI SRTDLIVDGD GLPHFLEVNV APGMTETSLL PMAVEAAGDD 

       310 
LGTLCRVLLE QAAARGAA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001814 Genomic DNA. Translation: ACZ91998.1.
RefSeqYP_003344741.1. NC_013595.1.

3D structure databases

ProteinModelPortalD2BEG1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ91998; ACZ91998; Sros_9380.
GeneID8672731.
KEGGsro:Sros_9380.
PATRIC32480617. VBIStrRos112010_9241.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011592.
KOK01921.
OMADYTARYT.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycSROS479432:GI0V-9468-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2BEG1_STRRD
AccessionPrimary (citable) accession number: D2BEG1
Entry history
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: June 11, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)