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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei149UniRule annotation1
Active sitei540UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Sros_1323Imported
OrganismiStreptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)Imported
Taxonomic identifieri479432 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptosporangialesStreptosporangiaceaeStreptosporangium
Proteomesi
  • UP000002029 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi479432.Sros_1323.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
HOGENOMiHOG000238647.
KOiK01595.
OMAiIAEAWHT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 2 hits.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.

Sequencei

Sequence statusi: Complete.

D2BD79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAIAHHQAE RSSAVTEMPD ELRADVRLLG ELLGQVIAEY GGDDLLADVE
60 70 80 90 100
RLRKAVIAAR RGKVSVDEIT AMVAEWPVER AVQIARAFTC YFHLANLAEE
110 120 130 140 150
HFRIRTLRVR DTGEEPLPES LAQAVQELGG ERVTELVEGL RLHPVLTAHP
160 170 180 190 200
TEARRRAVVT AIQRISGQLA AYNSPERGAA ERAETRRRLL EEIDLLWRTS
210 220 230 240 250
QLRSTKLDPL DEVRTAMAAF DETLFRVVPL VYRSLDAALG EGTGTREPLA
260 270 280 290 300
RPFIRYGSWI GGDRDGNPNV TAKVTRDAVL IQAEHVLIAL ENATHRIART
310 320 330 340 350
LTLTAGYTPA SPRLRAALTA AENDHPELVS EMATRSPQEP HRQWLLFVAA
360 370 380 390 400
RIVATRQRGL DLAYRSPEEL LGDLRTAQES LVAAGAERQA YGELQHLIWQ
410 420 430 440 450
VETFGFHLAE LEVRQHSQVH AAALAELAAG RTSERTDEVL ATIRTIGWIQ
460 470 480 490 500
ERYGVTACSR YVVSFTRSAD DIAAVYALAG HALGDKAPQL DVVPLFESGA
510 520 530 540 550
DLANAPGVLS GMLEIPGIQQ RLAANGRRLE VMLGYSDSAK ELGPAAATLK
560 570 580 590 600
LYEAQEALAA WAAEHDVRLT LFHGRGGALG RGGGPANRAV LAQAPGSVGG
610 620 630 640 650
RFKVTEQGEV IFARYGHAAI ARRHMEQVTS AVLLASTPSI EARTAEAAGR
660 670 680 690 700
FRGMAEQVAS ASEKAYRSLT EAPGFPEWFS LVSPLEEIGS LRLGSRPARR
710 720 730 740 750
GLGAPRSLDD LRAIPWVFAW AQTRVNLPGW YGLGSGLQAV ISESGLDELR
760 770 780 790 800
AAYREWPLFA SLLDNVEMSL AKTDRDIAAR YLALGGRDDF VEQVLREYDL
810 820 830 840 850
TRRLVLEITG HSRLLENRRV LSRAVQLRDP YVDALSHLQL RALSRLRADD
860 870
GLSEEERERL STLLLLSVNG VAAGLQNTG
Length:879
Mass (Da):96,316
Last modified:February 9, 2010 - v1
Checksum:i08480FFA0C40E082
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001814 Genomic DNA. Translation: ACZ84320.1.
RefSeqiWP_012888065.1. NC_013595.1.

Genome annotation databases

EnsemblBacteriaiACZ84320; ACZ84320; Sros_1323.
KEGGisro:Sros_1323.
PATRICi32464591. VBIStrRos112010_1297.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001814 Genomic DNA. Translation: ACZ84320.1.
RefSeqiWP_012888065.1. NC_013595.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi479432.Sros_1323.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACZ84320; ACZ84320; Sros_1323.
KEGGisro:Sros_1323.
PATRICi32464591. VBIStrRos112010_1297.

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
HOGENOMiHOG000238647.
KOiK01595.
OMAiIAEAWHT.
OrthoDBiPOG091H040O.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 2 hits.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD2BD79_STRRD
AccessioniPrimary (citable) accession number: D2BD79
Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: April 12, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.