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D2B6P9 (D2B6P9_STRRD) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length406 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII By similarity. HAMAP-Rule MF_01113

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP-Rule MF_01113 SAAS SAAS017961

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP-Rule MF_01113 SAAS SAAS017961

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01113 SAAS SAAS017961

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01113 SAAS SAAS017961.

Sequence similarities

Belongs to the DNA polymerase type-Y family. HAMAP-Rule MF_01113

Contains 1 umuC domain. HAMAP-Rule MF_01113

Contains umuC domain. SAAS SAAS017961

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain17 – 197181UmuC By similarity HAMAP-Rule MF_01113

Sites

Active site1161 By similarity HAMAP-Rule MF_01113
Metal binding211Magnesium By similarity HAMAP-Rule MF_01113
Metal binding1151Magnesium By similarity HAMAP-Rule MF_01113
Site261Substrate discrimination By similarity HAMAP-Rule MF_01113

Sequences

Sequence LengthMass (Da)Tools
D2B6P9 [UniParc].

Last modified February 9, 2010. Version 1.
Checksum: 1C7DB6439C0935BA

FASTA40643,698
        10         20         30         40         50         60 
MPRPGSDLGA DDTGCPILHV DMDAFYASVE LRERPELRGT PVVIGAPGAR GVVLSATYEA 

        70         80         90        100        110        120 
RRFGVHSAMP MTRARRLCPQ AVIIPPSRGK YAEVSRGVME IFHTFTPEVE PIASDEAFLD 

       130        140        150        160        170        180 
VGGARKRLGP PAAIAAMIRE QVVRKHGITC SVGVANSKFV AKLASQHCKP DGLLVVPAGR 

       190        200        210        220        230        240 
VVDFLHPLPV GALWGVGERT EQSLVRLGIR TVGDLAGVPV ATLQRQLGQA AGAHLAALAW 

       250        260        270        280        290        300 
GRDERPVTPH APDKSIGAEE TFATDIGDPV KIRVELLRLS ERVAARLREG GHVGRTVSVK 

       310        320        330        340        350        360 
LRRADFSTIS RSRTLREPTD VAQTLYATAC DLYAAAGLDR DRLRLVGVRV ENLSPAGEAT 

       370        380        390        400 
RQLGLGERET GWREAEQAMD RAARRFGRDV VLPASLVRPP FDGMAP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001814 Genomic DNA. Translation: ACZ85813.1.
RefSeqYP_003338556.1. NC_013595.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ85813; ACZ85813; Sros_2856.
GeneID8666142.
KEGGsro:Sros_2856.
PATRIC32467683. VBIStrRos112010_2835.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000082707.
KOK02346.
OMALWIFANG.
OrthoDBEOG6FZ4D8.

Enzyme and pathway databases

BioCycSROS479432:GI0V-2878-MONOMER.

Family and domain databases

Gene3D3.30.1490.100. 1 hit.
HAMAPMF_01113. DNApol_IV.
InterProIPR017961. DNA_pol_Y-fam_little_finger.
IPR001126. DNA_repair_prot_UmuC-like.
IPR017963. DNA_repair_prot_UmuC-like_N.
IPR022880. DNApol_IV.
IPR024728. PolY_HhH_motif.
[Graphical view]
PfamPF00817. IMS. 1 hit.
PF11799. IMS_C. 1 hit.
PF11798. IMS_HHH. 1 hit.
[Graphical view]
SUPFAMSSF100879. SSF100879. 1 hit.
PROSITEPS50173. UMUC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD2B6P9_STRRD
AccessionPrimary (citable) accession number: D2B6P9
Entry history
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: June 11, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)