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Protein

Xylose isomerase

Gene

xylA

Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei55UniRule annotation1
Active sitei58UniRule annotation1
Metal bindingi179Magnesium 1UniRule annotation1
Metal bindingi215Magnesium 1UniRule annotation1
Metal bindingi215Magnesium 2UniRule annotation1
Metal bindingi218Magnesium 2UniRule annotation1
Metal bindingi243Magnesium 1UniRule annotation1
Metal bindingi285Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Sros_0353Imported
OrganismiStreptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)Imported
Taxonomic identifieri479432 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptosporangialesStreptosporangiaceaeStreptosporangium
Proteomesi
  • UP000002029 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi479432.Sros_0353.

Structurei

3D structure databases

ProteinModelPortaliD2B0X8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 263AP_endonuc_2InterPro annotationAdd BLAST222

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
HOGENOMiHOG000022596.
KOiK01805.
OMAiYDQDLVF.
OrthoDBiPOG091H07LC.

Family and domain databases

HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiView protein in InterPro
IPR036237. Xyl_isomerase-like_sf.
IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
PANTHERiPTHR32176:SF0. PTHR32176:SF0. 1 hit.
PfamiView protein in Pfam
PF01261. AP_endonuc_2. 1 hit.
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
PROSITEiView protein in PROSITE
PS51415. XYLOSE_ISOMERASE. 1 hit.

Sequencei

Sequence statusi: Complete.

D2B0X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDYTPKPED RFTFGLWTVG WQARDQFGDA SRAPLDPVES VHRLAELGAY
60 70 80 90 100
GVTFHDDDLL AVEPDRDKAV ERFKKALAET GLKVPMATTN LFTHPVFKDG
110 120 130 140 150
GFTSNDRDVR RYALRKVMRN VDLAAELGAT TYVCWGGREG AESGAAKDIR
160 170 180 190 200
AALSRYKEGM DLLTSYVIDR GYDIRFAIEP KPNEPRGDIL LPTVGHALAF
210 220 230 240 250
INELEHSERV GLNPEVGHEE MAGLNFAHGI AQALWHGKLF HIDLNGQHGP
260 270 280 290 300
RFDQDLVFGH GDVKNSFFLV DLLENGGYDG PRHFDYKPLR TEDAEDVWVS
310 320 330 340 350
AAANMRTYLI LKEKVKAFHA DPEVVEARAA SRVAELSEPT LAPGETLEDL
360 370 380
HRDDFDVDRA AARGFHFSRL NQLALEHLLG VRG
Length:383
Mass (Da):42,749
Last modified:February 9, 2010 - v1
Checksum:iDDF6DA2E5CEAD8E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001814 Genomic DNA. Translation: ACZ83385.1.
RefSeqiWP_012887131.1. NC_013595.1.

Genome annotation databases

EnsemblBacteriaiACZ83385; ACZ83385; Sros_0353.
KEGGisro:Sros_0353.

Similar proteinsi

Entry informationi

Entry nameiD2B0X8_STRRD
AccessioniPrimary (citable) accession number: D2B0X8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: October 25, 2017
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported