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D2B0X8

- D2B0X8_STRRD

UniProt

D2B0X8 - D2B0X8_STRRD

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Protein

Xylose isomerase

Gene

xylA

Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Note: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei55 – 551UniRule annotation
Active sitei58 – 581UniRule annotation
Metal bindingi179 – 1791Magnesium 1UniRule annotation
Metal bindingi215 – 2151Magnesium 1UniRule annotation
Metal bindingi215 – 2151Magnesium 2UniRule annotation
Metal bindingi218 – 2181Magnesium 2UniRule annotation
Metal bindingi243 – 2431Magnesium 1UniRule annotation
Metal bindingi253 – 2531Magnesium 2UniRule annotation
Metal bindingi255 – 2551Magnesium 2UniRule annotation
Metal bindingi285 – 2851Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciSROS479432:GI0V-359-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Sros_0353Imported
OrganismiStreptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)Imported
Taxonomic identifieri479432 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeStreptosporangiaceaeStreptosporangium
ProteomesiUP000002029: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD2B0X8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000022596.
KOiK01805.
OMAiFAHETMA.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2B0X8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDYTPKPED RFTFGLWTVG WQARDQFGDA SRAPLDPVES VHRLAELGAY
60 70 80 90 100
GVTFHDDDLL AVEPDRDKAV ERFKKALAET GLKVPMATTN LFTHPVFKDG
110 120 130 140 150
GFTSNDRDVR RYALRKVMRN VDLAAELGAT TYVCWGGREG AESGAAKDIR
160 170 180 190 200
AALSRYKEGM DLLTSYVIDR GYDIRFAIEP KPNEPRGDIL LPTVGHALAF
210 220 230 240 250
INELEHSERV GLNPEVGHEE MAGLNFAHGI AQALWHGKLF HIDLNGQHGP
260 270 280 290 300
RFDQDLVFGH GDVKNSFFLV DLLENGGYDG PRHFDYKPLR TEDAEDVWVS
310 320 330 340 350
AAANMRTYLI LKEKVKAFHA DPEVVEARAA SRVAELSEPT LAPGETLEDL
360 370 380
HRDDFDVDRA AARGFHFSRL NQLALEHLLG VRG
Length:383
Mass (Da):42,749
Last modified:February 9, 2010 - v1
Checksum:iDDF6DA2E5CEAD8E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001814 Genomic DNA. Translation: ACZ83385.1.
RefSeqiYP_003336128.1. NC_013595.1.

Genome annotation databases

EnsemblBacteriaiACZ83385; ACZ83385; Sros_0353.
GeneIDi8663621.
KEGGisro:Sros_0353.
PATRICi32462666. VBIStrRos112010_0342.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001814 Genomic DNA. Translation: ACZ83385.1 .
RefSeqi YP_003336128.1. NC_013595.1.

3D structure databases

ProteinModelPortali D2B0X8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACZ83385 ; ACZ83385 ; Sros_0353 .
GeneIDi 8663621.
KEGGi sro:Sros_0353.
PATRICi 32462666. VBIStrRos112010_0342.

Phylogenomic databases

HOGENOMi HOG000022596.
KOi K01805.
OMAi FAHETMA.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci SROS479432:GI0V-359-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02631. xylA_Arthro. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100Imported.

Entry informationi

Entry nameiD2B0X8_STRRD
AccessioniPrimary (citable) accession number: D2B0X8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: November 26, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3