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D2B0X8

- D2B0X8_STRRD

UniProt

D2B0X8 - D2B0X8_STRRD

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Protein
Xylose isomerase
Gene
xylA, Sros_0353
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei55 – 551 By similarityUniRule annotation
Active sitei58 – 581 By similarityUniRule annotation
Metal bindingi179 – 1791Magnesium 1 By similarityUniRule annotation
Metal bindingi215 – 2151Magnesium 1 By similarityUniRule annotation
Metal bindingi215 – 2151Magnesium 2 By similarityUniRule annotation
Metal bindingi218 – 2181Magnesium 2 By similarityUniRule annotation
Metal bindingi243 – 2431Magnesium 1 By similarityUniRule annotation
Metal bindingi253 – 2531Magnesium 2 By similarityUniRule annotation
Metal bindingi255 – 2551Magnesium 2 By similarityUniRule annotation
Metal bindingi285 – 2851Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciSROS479432:GI0V-359-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Sros_0353Imported
OrganismiStreptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)Imported
Taxonomic identifieri479432 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeStreptosporangiaceaeStreptosporangium
ProteomesiUP000002029: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD2B0X8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000022596.
KOiK01805.
OMAiFAHETMA.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D2B0X8-1 [UniParc]FASTAAdd to Basket

« Hide

MSDYTPKPED RFTFGLWTVG WQARDQFGDA SRAPLDPVES VHRLAELGAY    50
GVTFHDDDLL AVEPDRDKAV ERFKKALAET GLKVPMATTN LFTHPVFKDG 100
GFTSNDRDVR RYALRKVMRN VDLAAELGAT TYVCWGGREG AESGAAKDIR 150
AALSRYKEGM DLLTSYVIDR GYDIRFAIEP KPNEPRGDIL LPTVGHALAF 200
INELEHSERV GLNPEVGHEE MAGLNFAHGI AQALWHGKLF HIDLNGQHGP 250
RFDQDLVFGH GDVKNSFFLV DLLENGGYDG PRHFDYKPLR TEDAEDVWVS 300
AAANMRTYLI LKEKVKAFHA DPEVVEARAA SRVAELSEPT LAPGETLEDL 350
HRDDFDVDRA AARGFHFSRL NQLALEHLLG VRG 383
Length:383
Mass (Da):42,749
Last modified:February 9, 2010 - v1
Checksum:iDDF6DA2E5CEAD8E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001814 Genomic DNA. Translation: ACZ83385.1.
RefSeqiYP_003336128.1. NC_013595.1.

Genome annotation databases

EnsemblBacteriaiACZ83385; ACZ83385; Sros_0353.
GeneIDi8663621.
KEGGisro:Sros_0353.
PATRICi32462666. VBIStrRos112010_0342.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001814 Genomic DNA. Translation: ACZ83385.1 .
RefSeqi YP_003336128.1. NC_013595.1.

3D structure databases

ProteinModelPortali D2B0X8.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACZ83385 ; ACZ83385 ; Sros_0353 .
GeneIDi 8663621.
KEGGi sro:Sros_0353.
PATRICi 32462666. VBIStrRos112010_0342.

Phylogenomic databases

HOGENOMi HOG000022596.
KOi K01805.
OMAi FAHETMA.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci SROS479432:GI0V-359-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02631. xylA_Arthro. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100.

Entry informationi

Entry nameiD2B0X8_STRRD
AccessioniPrimary (citable) accession number: D2B0X8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: June 11, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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