D2AMI2 (D2AMI2_FRATE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase HAMAP-Rule MF_00083
Short name=PTH HAMAP-Rule MF_00083
EC=3.1.1.29 HAMAP-Rule MF_00083

Gene names

Name:	pth HAMAP-Rule MF_00083
Ordered Locus Names:	NE061598_03885

Organism

Francisella tularensis subsp. tularensis (strain NE061598) [Complete proteome] [HAMAP]

Taxonomic identifier

510831 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella › Francisella tularensis › Francisella tularensis subsp. tularensis

Protein attributes

Sequence length	191 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP-Rule MF_00083
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP-Rule MF_00083 RuleBase RU000673
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00083
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00083.
Sequence similarities	Belongs to the PTH family. HAMAP-Rule MF_00083 RuleBase RU004320

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00083
Molecular function	Hydrolase HAMAP-Rule MF_00083 RuleBase RU000673 EMBL ADA78365.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D2AMI2 [UniParc]. Last modified February 9, 2010. Version 1. Checksum: 983F0CCC7718660A	FASTA	191	21,137
	10 20 30 40 50 60 MPKIKMIIGL GNIGKEYQDT RHNVGEWFIA KIAQDNNQSF SSNPKLNCNL AKVSIDYNNV 70 80 90 100 110 120 VLVFPTTYMN NSGLAVSKVA NFYKIAPAEI LVVHDELDID SGEIRLKKGG GHGGHNGLRS 130 140 150 160 170 180 INQHLGTNDY LRLRIGIGHP GHKSKVANYV LSNPSIAQKK DIDSAIDNGI CFLDDIINYK 190 LEPVMQKLHT K

References

[1]

"Large direct repeats flank genomic rearrangements between a new clinical isolate of Francisella tularensis subsp. tularensis A1 and Schu S4." Nalbantoglu U., Sayood K., Dempsey M.P., Iwen P.C., Francesconi S.C., Barabote R.D., Xie G., Brettin T.S., Hinrichs S.H., Fey P.D. PLoS ONE 5:E9007-E9007(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NE061598.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001633 Genomic DNA. Translation: ADA78365.1.
RefSeq	YP_005830845.1. NC_017453.1.
3D structure databases
ProteinModelPortal	D2AMI2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADA78365; ADA78365; NE061598_03885.
GeneID	12437354.
KEGG	ftr:NE061598_03885.
PATRIC	36818350. VBIFraTul19263_0781.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000004796.
KO	K01056.
OMA	FSSKHNA.
Family and domain databases
Gene3D	3.40.50.1470. 1 hit.
HAMAP	MF_00083. Pept_tRNA_hydro_bact.
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
PANTHER	PTHR17224. PTHR17224. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
SUPFAM	SSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMs	TIGR00447. pth. 1 hit.
PROSITE	PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D2AMI2_FRATE

Accession

Primary (citable) accession number: D2AMI2

Entry history

Integrated into UniProtKB/TrEMBL:	February 9, 2010
Last sequence update:	February 9, 2010
Last modified:	May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)