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D2ADF5 (D2ADF5_SHIF2) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Alanine racemase, biosynthetic EMBL ADA76446.1
Gene names
Name:alr EMBL ADA76446.1
Ordered Locus Names:SFxv_4528 EMBL ADA76446.1
OrganismShigella flexneri serotype X (strain 2002017) [Complete proteome] [HAMAP] EMBL ADA76446.1
Taxonomic identifier591020 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella ›

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622

Sequence similarities

Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
   LigandPyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
   Molecular functionIsomerase SAAS SAAS020622 RuleBase RU000608
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-alanine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionalanine racemase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D2ADF5 [UniParc].

Last modified February 9, 2010. Version 1.
Checksum: FDE9B438115342C2

FASTA35939,153
        10         20         30         40         50         60 
MQAATVVINR RALRHNLQRL RELAPASKMV AVVKANAYGH GLLETARTLP DADAFGVARL 

        70         80         90        100        110        120 
EEALRLRAGG ITKPVLLLEG FFDARDLPTI SAQHFHTAVH NEEQLAALEE ASLDEPVTVW 

       130        140        150        160        170        180 
MKLDTGMHRL GVRPEQAEAF YHRLTQCKNV RQPVNIVSHF ARADEPKCGA TEKQLAIFNT 

       190        200        210        220        230        240 
FCEGKPGQRS IAASGGILLW PQSHFDWVRP GIILYGVSPL EDRSTGADFG CQPVMSLTSS 

       250        260        270        280        290        300 
LIAVREHKAG EPVGYGGTWV SERDTRLGVV AMGYGDGYPR AAPSGTPVLV NGREVPIVGR 

       310        320        330        340        350 
VAMDMICVDL GPQAQDKAGD PVILWGEGLP VERIAEMTKV SAYELITRLT SRVAMKYVD

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References

[1]"Emergence of a new multidrug resistance serotype X variant in an epidemic clone of Shigella flexneri."
Ye C., Lan R., Xia S., Zhang J., Sun Q., Zhang S., Jing H., Wang L., Li Z., Zhou Z., Zhao A., Cui Z., Cao J., Jin D., Huang L., Wang Y., Luo X., Bai X. expand/collapse author list , Wang Y., Wang P., Xu Q., Xu J.
J. Clin. Microbiol. 48:419-426(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2002017 EMBL ADA76446.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001383 Genomic DNA. Translation: ADA76446.1.
RefSeqYP_005729739.1. NC_017328.1.

3D structure databases

ProteinModelPortalD2ADF5.
SMRD2ADF5. Positions 1-359.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADA76446; ADA76446; SFxv_4528.
GeneID12317782.
KEGGsfe:SFxv_4528.
PATRIC36751232. VBIShiFle60233_4864.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031446.
KOK01775.

Enzyme and pathway databases

UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

BindingDBD2ADF5.

Entry information

Entry nameD2ADF5_SHIF2
AccessionPrimary (citable) accession number: D2ADF5
Entry history
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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