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Protein
Submitted name:

Uncharacterized protein

Gene

TcasGA2_TC014979

Organism
Tribolium castaneum (Red flour beetle)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:TcasGA2_TC014979Imported
OrganismiTribolium castaneum (Red flour beetle)Imported
Taxonomic identifieri7070 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaColeopteraPolyphagaCucujiformiaTenebrionidaeTenebrionidae incertae sedisTribolium
Proteomesi
  • UP000007266 Componenti: Linkage group 6

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei43 – 7230HelicalSequence analysisAdd
BLAST
Transmembranei173 – 19220HelicalSequence analysisAdd
BLAST
Transmembranei204 – 22522HelicalSequence analysisAdd
BLAST
Transmembranei322 – 34524HelicalSequence analysisAdd
BLAST
Transmembranei384 – 40724HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliD2A6I4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini169 – 22658Ion_trans_2InterPro annotationAdd
BLAST
Domaini332 – 40978Ion_trans_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
InParanoidiD2A6I4.
OMAiLENWSIL.
OrthoDBiEOG7BZVT3.
PhylomeDBiD2A6I4.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

D2A6I4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKDSHYCYE PYQKSNSLKR DTKKKSSESC RCFGKSRKSR TKAFFTGLAT
60 70 80 90 100
NLGICILLFG YTLIGSVIFL AIEGGSTFQH STQILATTSG KKFLNHSAEF
110 120 130 140 150
KAKNDEARAR TVENIWDITV NLNILYRDNW TRLAAQEITR FQDELLKSLG
160 170 180 190 200
EELAAQPVQE KAERRAGEYE WTFAKAFLYS LTVLTTIGYG SIAPRTTLGK
210 220 230 240 250
AVTMGYAMLG IPLTLLYLSS IGSILSRVAR GVFSRALCCC LCSNCGYCCY
260 270 280 290 300
DEKRMAEKER RMKKKRQQME LQQQMALQEP FYVRSNSIHN SLHSPIRDGG
310 320 330 340 350
VKEIDSLSTD NESKSSMHGL SILAPILLCL AMMFIYICLG TFALYKLENW
360 370 380 390 400
SILDGFYFCF MSLTTIGFGD MVPGSDPFGR ESNTTIWFCS IYIMSGMALT
410 420 430 440
AMCFNVVHDE IVHRLKHQEK IAPKVNSASY ADDLNSSDPY NMTS
Length:444
Mass (Da):50,020
Last modified:February 9, 2010 - v1
Checksum:i994DE4F9F16ACF6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ971348 Genomic DNA. Translation: EFA04915.1.
RefSeqiXP_008191956.1. XM_008193734.2.
XP_015836606.1. XM_015981120.1.

Genome annotation databases

EnsemblMetazoaiTC014979-RA; TC014979-PA; TC014979.
GeneIDi659728.
KEGGitca:659728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KQ971348 Genomic DNA. Translation: EFA04915.1.
RefSeqiXP_008191956.1. XM_008193734.2.
XP_015836606.1. XM_015981120.1.

3D structure databases

ProteinModelPortaliD2A6I4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiTC014979-RA; TC014979-PA; TC014979.
GeneIDi659728.
KEGGitca:659728.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
InParanoidiD2A6I4.
OMAiLENWSIL.
OrthoDBiEOG7BZVT3.
PhylomeDBiD2A6I4.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome of the model beetle and pest Tribolium castaneum."
    Tribolium Genome Sequencing Consortium
    Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R., Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M., Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S., Schroder R., Tautz D.
    , Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M., Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D., Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H., Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J., Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S., Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B., Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R., Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L., Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y., Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G., Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J., Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V., Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S., Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B., Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W., Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V., Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M., Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M., Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D., Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E., Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M., Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N., Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C., Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H., Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M., Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R., Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J., Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B., Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C., Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B., Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H., Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y., Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P., Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S., Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W., Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.
    Nature 452:949-955(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Georgia GA2Imported.
  2. "BeetleBase in 2010: revisions to provide comprehensive genomic information for Tribolium castaneum."
    Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W., Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.
    Nucleic Acids Res. 38:D437-D442(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: Georgia GA2Imported.

Entry informationi

Entry nameiD2A6I4_TRICA
AccessioniPrimary (citable) accession number: D2A6I4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2010
Last sequence update: February 9, 2010
Last modified: July 6, 2016
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.