D1FNM8 (D1FNM8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Plasma membrane Ca++ transporting ATPase 4 variant x/e EMBL ACC91879.2

Gene names

Name:

Atp2b4 EMBL ACC91879.2 MGI 88111

Organism

Mus musculus (Mouse) EMBL ACC91879.2

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1166 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS006068
Ligand	ATP-binding RuleBase RU000653 SAAS SAAS006068 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS018303 RuleBase RU000653
PTM	Phosphoprotein SAAS SAAS006068
Gene Ontology (GO)
Biological_process	calcium ion transport Traceable author statement PubMed 12660151. Source: MGI
Cellular_component	integral to plasma membrane Traceable author statement PubMed 12660151. Source: MGI
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calcium-transporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D1FNM8 [UniParc]. Last modified March 21, 2012. Version 2. Checksum: 1A9DA75973DC88D1	FASTA	1,166	128,548
	10 20 30 40 50 60 MTNPPGQSVS ANTVAESHEG EFGCTLMDLR KLMELRGADA VAQISAHYGG VQEICTRLKT 70 80 90 100 110 120 SPIEGLSGNP ADLEKRRLVF GKNVIPPKRP KTFLELVWEA LQDVTLIILE IAAVISLVLS 130 140 150 160 170 180 FYRPPGGDNE ICGHIASSPE EEEEGETGWI EGAAILASVI IVVLVTAFND WSKEKQFRGL 190 200 210 220 230 240 QSRIELEQKF SIIRNGQLIQ LPVAEIVVGD IAQIKYGDLL PADGILIQGN DLKIDESSLT 250 260 270 280 290 300 GESDHVKKTL DKDPMLLSGT HVMEGSGRMV VTAVGVNSQT GIIFTLLGAS EEEDDDDKKK 310 320 330 340 350 360 KGKKQGAPEN RNKAKTQDGV ALEIQPLNSQ EGLDSEDKEK KIARIPKKEK SVLQGKLTRL 370 380 390 400 410 420 AVQIGKAGLI MSVLTVVILI LYFVVDNFVI QRREWLPECT PVYIQYFVKF FIIGVTVLVV 430 440 450 460 470 480 AVPEGLPLAV TISLAYSVKK MMKDNNLVRH LDACETMGNA TAICSDKTGT LTMNRMTVVQ 490 500 510 520 530 540 AYIGGTHYRQ IPQPDVFPPK VLELIVNGIS INCAYTSKIQ PPEKEGGLPR QVGNKTECGL 550 560 570 580 590 600 LGFVTDLKQD YQAVRNEVPE EKLFKVYTFN SVRKSMSTVI RKPEGGFRMF SKGASEIMLR 610 620 630 640 650 660 RCDRILNKEG EIKSFRSKDR DNMVRNVIEP MASEGLRTIC LAYRDFDGTE PSWDIEGEIL 670 680 690 700 710 720 TSLICIAVVG IEDPVRPEVP DAIAKCKRAG ITVRMVTGDN VNTARAIATK CGILTPKDDF 730 740 750 760 770 780 LCLEGKEFNS LIRNEKGEVE QEKLDKIWPK LRVLARSSPT DKHTLVKGII DSTAGEQRQV 790 800 810 820 830 840 VAVTGDGTND GPALKKADVG FAMGIAGTDV AKEASDIILT DDNFTSIVKA VMWGRNVYDS 850 860 870 880 890 900 ISKFLQFQLT VNVVAVIVAF TGACITQDSP LKAVQMLWVN LIMDTFASLA LATEPPTESL 910 920 930 940 950 960 LRRRPYGRNK PLISRTMMKN ILGHAVYQLL IVFLLVFAGD TLFDIDSGRK APLNSPPSQH 970 980 990 1000 1010 1020 YTIVFNTFVL MQLFNEINAR KIHGEKNVFA GVYRNIIFCT VVLGTFFCQI MIVELGGKPF 1030 1040 1050 1060 1070 1080 SCTSLTMEQW MWCLFIGIGE LLWGQVISAI PTKSLKFLKE AGHGSDKEDI SRDTEGMDEI 1090 1100 1110 1120 1130 1140 DLAEMELRRG QILWVRGLNR IQTQIDVINK FQTEAPLKRV RENMTQHLDV KLVPSSYSAA 1150 1160 VASLRTCPSI SSAISSAVTS PPVGSE

References

[1]	"Regulated Alternative Splicing of a Novel and a Classical Exon-20 of PMCA4." Afroze T., Yang G., Khoshbin A., Tanwir M., Tabish T., Momen A., Elias C., Backx P., Husain M. Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL ACC91879.2. Tissue: Brain EMBL ACC91879.2.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU493094 mRNA. Translation: ACC91879.2.
RefSeq	NP_001161421.1. NM_001167949.2.
UniGene	Mm.188617.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	381290.
KEGG	mmu:381290.
UCSC	uc011wsc.1. mouse.
Organism-specific databases
CTD	493.
MGI	MGI:88111. Atp2b4.
Phylogenomic databases
HOGENOM	HOG000265623.
KO	K05850.
Family and domain databases
Gene3D	1.20.1110.10. 3 hits.
InterPro	IPR022141. ATP_Ca_trans_C. IPR006408. ATPase_P-typ_Ca-transp_plasma. IPR006068. ATPase_P-typ_cation-transptr_C. IPR004014. ATPase_P-typ_cation-transptr_N. IPR018303. ATPase_P-typ_P_site. IPR023298. ATPase_P-typ_TM_dom. IPR008250. ATPase_P-typ_transduc_dom_A. IPR001757. Cation_transp_P_typ_ATPase. IPR023214. HAD-like_dom. [Graphical view]
PANTHER	PTHR24093. PTHR24093. 1 hit.
Pfam	PF12424. ATP_Ca_trans_C. 1 hit. PF00689. Cation_ATPase_C. 1 hit. PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01517. ATPase-IIB_Ca. 1 hit. TIGR01494. ATPase_P-type. 3 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	401842.
SOURCE	Search...

Entry information

Entry name

D1FNM8_MOUSE

Accession

Primary (citable) accession number: D1FNM8

Entry history

Integrated into UniProtKB/TrEMBL:	January 19, 2010
Last sequence update:	March 21, 2012
Last modified:	May 1, 2013
This is version 33 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)