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Protein

Amino-acid acetyltransferase

Gene

argA

Organism
Neisseria gonorrhoeae SK-93-1035
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. acetyl-CoA:L-glutamate N-acetyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00068; UER00106.

Names & Taxonomyi

Protein namesi
Recommended name:
Amino-acid acetyltransferaseUniRule annotation (EC:2.3.1.-UniRule annotation, EC:2.3.1.1UniRule annotation)
Alternative name(s):
N-acetylglutamate synthaseUniRule annotation
Gene namesi
Name:argAUniRule annotation
ORF Names:NGLG_00316Imported
OrganismiNeisseria gonorrhoeae SK-93-1035Imported
Taxonomic identifieri528360 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD1ED56.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini287 – 436150N-acetyltransferaseUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the acetyltransferase family. ArgA subfamily.UniRule annotation
Contains 1 N-acetyltransferase domain.UniRule annotation
Contains N-acetyltransferase domain.SAAS annotation

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
3.40.630.30. 1 hit.
HAMAPiMF_01105. N_acetyl_glu_synth.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR000182. GNAT_dom.
IPR010167. NH2A_AcTrfase_ArgA.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF00583. Acetyltransf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000423. ArgA. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
SSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D1ED56-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNAPDSFVAH FREAAPYIRQ MRGTTLVAGI DGRLLEGGTL NKLAADIGLL
60 70 80 90 100
SQLGIRLVLI HGAYHFLDRL AAAQGRTPHY CRGLRVTDET SLGQAQQFAG
110 120 130 140 150
TVRSRFEAAL CGSVSGFARA PSVPLVSGNF LTARPIGVID GTDMEYAGVI
160 170 180 190 200
RKTDTAALRF QLDAGNIVWM PPLGHSYGGK TFNLDMVQAA ASVAVSLQAE
210 220 230 240 250
KLVYLTLSDG ISRPDGTLAE TLSAQEAQSL AEHAASETRR LISSAVAALE
260 270 280 290 300
GGVHRVQILN GAADGSLLQE LFTRNGIGTS IAKEAFVSIR QAHSGDIPHI
310 320 330 340 350
AALIRPLEEQ GILLHRSREY LENHISEFSI LEHDGNLYGC AALKTFAEAD
360 370 380 390 400
CGEIACLAVS PQAQDGGYGE RLLAHIIDKA RGIGISRLFA LSTNTGEWFA
410 420 430
ERGFQTASED ELPETRRKDY RSNGRNSHIL VRRLHR
Length:436
Mass (Da):47,006
Last modified:January 19, 2010 - v1
Checksum:iE29044A0B76C7B02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973086 Genomic DNA. Translation: EEZ58476.1.

Genome annotation databases

EnsemblBacteriaiEEZ58476; EEZ58476; NGLG_00316.
PATRICi28195341. VBINeiGon43547_0285.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ973086 Genomic DNA. Translation: EEZ58476.1.

3D structure databases

ProteinModelPortaliD1ED56.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiEEZ58476; EEZ58476; NGLG_00316.
PATRICi28195341. VBINeiGon43547_0285.

Enzyme and pathway databases

UniPathwayiUPA00068; UER00106.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
3.40.630.30. 1 hit.
HAMAPiMF_01105. N_acetyl_glu_synth.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR000182. GNAT_dom.
IPR010167. NH2A_AcTrfase_ArgA.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
PF00583. Acetyltransf_1. 1 hit.
[Graphical view]
PIRSFiPIRSF000423. ArgA. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
SSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SK-93-1035Imported.

Entry informationi

Entry nameiD1ED56_NEIGO
AccessioniPrimary (citable) accession number: D1ED56
Entry historyi
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: February 4, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.UniRule annotation

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.