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D1CIB0 (D1CIB0_THET1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cysteine--tRNA ligase HAMAP-Rule MF_00041
EC=6.1.1.16 HAMAP-Rule MF_00041
Alternative name(s):
Cysteinyl-tRNA synthetase HAMAP-Rule MF_00041
Gene names
Name:cysS HAMAP-Rule MF_00041
Ordered Locus Names:Tter_2592
OrganismThermobaculum terrenum (strain ATCC BAA-798 / YNP1) [Complete proteome] [HAMAP] EMBL ACZ43481.1
Taxonomic identifier525904 [NCBI]
Taxonomic lineageBacteria › Thermobaculum ›

Protein attributes

Sequence length785 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys). HAMAP-Rule MF_00041 SAAS SAAS015273

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00041

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00041

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00041 SAAS SAAS015273.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00041

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif29 – 3911"HIGH" region By similarity HAMAP-Rule MF_00041
Motif275 – 2795"KMSKS" region By similarity HAMAP-Rule MF_00041

Sites

Metal binding271Zinc By similarity HAMAP-Rule MF_00041
Metal binding2181Zinc By similarity HAMAP-Rule MF_00041
Metal binding2431Zinc By similarity HAMAP-Rule MF_00041
Metal binding2471Zinc By similarity HAMAP-Rule MF_00041
Binding site2781ATP By similarity HAMAP-Rule MF_00041

Sequences

Sequence LengthMass (Da)Tools
D1CIB0 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: A317A2BF0D277457

FASTA78590,295
        10         20         30         40         50         60 
MRLYNTLTRR VEEVVPVEPG RIRMYTCGPT VYRYIHIGNL RSFCTADWIR RALLREGYEV 

        70         80         90        100        110        120 
IHVKNITDVG HMRQELLDQG EDKLEAEARR VGRTPGEIAE FYTRAFMRDE ARMNILPASV 

       130        140        150        160        170        180 
FPRATQHVGE MIEIVRELER QGYAYRAGGN VYFDVARLPQ YGQLSGNSLP ELTSSQEDAT 

       190        200        210        220        230        240 
ADKRSPLDFA LWKEAEPGRL MAWDSPWGRG FPGWHIECTA MAIKYLGTEI DIHTGGVDNI 

       250        260        270        280        290        300 
FPHHENERAQ SEAYVGHRWV RHWVHTQHLL TDGLKMSKSM SNDYTLDDIV ARGFEPLALR 

       310        320        330        340        350        360 
YLFTTAHYRT RLNFTFRALA GAQTSLRRLR MAALAARDEA VAPPDEEAMR PWREAFDRSL 

       370        380        390        400        410        420 
RDDLNLPAAM AVVWDVVRRS GLGPAERAAL LAEFDEVLGL DVFAEPDSGL LLEPRQDVRE 

       430        440        450        460        470        480 
LLALRAEVRA RGDYALADAL RSDLEARGVE LRDTRQGTRA YRLRINRLPH VFTSSAEVPS 

       490        500        510        520        530        540 
RVGEPDRYEW SVNLIARNNR EDLERCLRSL ARHLHGRSLE VVVVDSGSTD DTLGLMLELY 

       550        560        570        580        590        600 
HRGYWEEEGV RVPLKVLFAD HNIGFAASRN ATMRASEGWY VVWLDTSVEL AGDVWTPLEE 

       610        620        630        640        650        660 
ALADRSVGVA GPFGLVTEDL REFERTPGPD ADAMEGYLFA FRRALLEEVG LLDNEKFRFY 

       670        680        690        700        710        720 
RLADVYYSFF FKAAGLRVVV VPEVERRIIL HPHREWYSLL PEERQTKSKH NYDLFRARWH 

       730        740        750        760        770        780 
HGESLLVARD GQVERWLEHD HPRHVDADHF HPPEELPPPG VPHVHPHRHL PDHQHNHPHY 


HFQGD

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001826 Genomic DNA. Translation: ACZ43481.1.
RefSeqYP_003324303.1. NC_013526.1.

3D structure databases

ProteinModelPortalD1CIB0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ43481; ACZ43481; Tter_2592.
GeneID8640621.
KEGGttr:Tter_2592.
PATRIC32505611. VBITheTer68767_2765.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01883.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00041. Cys_tRNA_synth.
InterProIPR015803. Cys-tRNA-ligase.
IPR015273. Cys-tRNA-synt_Ia_DALR.
IPR024909. Cys-tRNA/MSH_ligase.
IPR001173. Glyco_trans_2.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR10890. PTHR10890. 1 hit.
PfamPF00535. Glycos_transf_2. 1 hit.
PF01406. tRNA-synt_1e. 1 hit.
[Graphical view]
PRINTSPR00983. TRNASYNTHCYS.
SMARTSM00840. DALR_2. 1 hit.
[Graphical view]
SUPFAMSSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMsTIGR00435. cysS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD1CIB0_THET1
AccessionPrimary (citable) accession number: D1CIB0
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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