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D1CDJ3 (D1CDJ3_THET1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate--tRNA ligase HAMAP-Rule MF_00022
EC=6.1.1.17 HAMAP-Rule MF_00022
Alternative name(s):
Glutamyl-tRNA synthetase HAMAP-Rule MF_00022
Gene names
Name:gltX HAMAP-Rule MF_00022
Ordered Locus Names:Tter_0077
OrganismThermobaculum terrenum (strain ATCC BAA-798 / YNP1) [Complete proteome] [HAMAP] EMBL ACZ40999.1
Taxonomic identifier525904 [NCBI]
Taxonomic lineageBacteria › Thermobaculum ›

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity. HAMAP-Rule MF_00022

Catalytic activity

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). HAMAP-Rule MF_00022

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00022

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00022.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00022 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif11 – 2111"HIGH" region By similarity HAMAP-Rule MF_00022
Motif252 – 2565"KMSKS" region By similarity HAMAP-Rule MF_00022

Sites

Binding site2551ATP By similarity HAMAP-Rule MF_00022

Sequences

Sequence LengthMass (Da)Tools
D1CDJ3 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 6F0374557C5527BA

FASTA49255,666
        10         20         30         40         50         60 
MNSEVRVRFP PSPTGYLHVG NLRTAVFNWL LARHHGGKFI LRIEDTDRAR VVPGAVEVIY 

        70         80         90        100        110        120 
ETLRWIGIDW DEGPDIGGPH APYVQSERKE IYREYAELLI SQGKAYRCFC SQERLEALRE 

       130        140        150        160        170        180 
EQRKNNLPTR YDRKCRYLGP EEAKRLVDSG QPYVVRFATP LEGTTTMVDL LRGPVTYQND 

       190        200        210        220        230        240 
QIDDFVILKS DGYPPYHFAV VVDDHLMGIT HVLRGDEYIS SGARDILLHE ALGWNPPLYA 

       250        260        270        280        290        300 
HTAIILGPDR SRLSKRHGAL PALEYRDIGI IPEAMFNYLA LLGASYSADR EIFSREELIE 

       310        320        330        340        350        360 
LFDIDKMSPS PAIFDANKLE WMNAYYINHV LSVDDLASRV KPILENAGLV KTEDLDEGYL 

       370        380        390        400        410        420 
IEVIGLVKDR IKLLPDVVEL TDFFFRDPDP SAEEIAGKKL TLQEAQELLQ KVKDRVSPID 

       430        440        450        460        470        480 
NWSEEILETE LRSMASELGV KTGTLFMLIR VAITGKTASP GLFETMAVLG KDRTISRIGR 

       490 
AIDKLDLVVH GG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001825 Genomic DNA. Translation: ACZ40999.1.
RefSeqYP_003321821.1. NC_013525.1.

3D structure databases

ProteinModelPortalD1CDJ3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ40999; ACZ40999; Tter_0077.
GeneID8644533.
KEGGttr:Tter_0077.
PATRIC32500130. VBITheTer68767_0080.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000252720.
KOK01885.
OMARYRDFKG.

Family and domain databases

Gene3D1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
1.10.8.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00022_B. Glu_tRNA_synth_B.
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020752. aa-tRNA-synth_I_codon-bd_sub1.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_Ib_bac/mito.
IPR000924. Glu/Gln-tRNA-synth_Ib.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PTHR10119:SF1. PTHR10119:SF1. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00464. gltX_bact. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1CDJ3_THET1
AccessionPrimary (citable) accession number: D1CDJ3
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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