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D1CBZ1 (D1CBZ1_THET1) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable DNA ligase HAMAP-Rule MF_00407

EC=6.5.1.1 HAMAP-Rule MF_00407
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:Tter_1400 EMBL ACZ42306.1
OrganismThermobaculum terrenum (strain ATCC BAA-798 / YNP1) [Complete proteome] [HAMAP] EMBL ACZ42306.1
Taxonomic identifier525904 [NCBI]
Taxonomic lineageBacteriaThermobaculum

Protein attributes

Sequence length583 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407 RuleBase RU004196

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2511N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2491ATP By similarity HAMAP-Rule MF_00407
Binding site2561ATP By similarity HAMAP-Rule MF_00407
Binding site2711ATP By similarity HAMAP-Rule MF_00407
Binding site3011ATP By similarity HAMAP-Rule MF_00407
Binding site3411ATP By similarity HAMAP-Rule MF_00407
Binding site4161ATP By similarity HAMAP-Rule MF_00407
Binding site4221ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
D1CBZ1 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 8544A91BE3F310BE

FASTA58365,106
        10         20         30         40         50         60 
MLFSKLAEYF EQLDHTTSRN TLVAILADLY SQCDQSEVRP ITYLLQGRLA PFFKPIEIGM 

        70         80         90        100        110        120 
GINYVADAIG KAFGVDRKHV MQVFDRVGDI GTAARQVQQE AGKELSMEET PTVLEIFNQL 

       130        140        150        160        170        180 
MAISQVSGQG SIEKKIGMFA DILQKLDPRS VTYICRIPVG TLRLGVGDPT ILDALSFAKS 

       190        200        210        220        230        240 
GDKSLRKPLE RAYNETSDLG LIAETLWKDG IEGVEKLSIM PGNPVRPALA ERLPTPEAII 

       250        260        270        280        290        300 
NRMGQCAVEK KYDGFRCQVH KIGNEVKIFS RNLEDMTGMF PEITSGTLAM VDAETAIFEG 

       310        320        330        340        350        360 
EALAYHPLSG EFLPFQVTTK RRRKHKIEEA AQELPLKLFA FDILYKNGEN LMGMKYVDRR 

       370        380        390        400        410        420 
EILANTIKGE DSLIVSDWVI ADNVEKLMEV FNEAIESGLE GIVAKRLDSP YQAGARNFNW 

       430        440        450        460        470        480 
VKLKRTHAGQ LQDTVDCVIV GYIYGRGKRA QLGAGALLVA VYNPDKDTFQ TITKIGTGLT 

       490        500        510        520        530        540 
DEEWKEVVER CKPYVTEEKP ARVESIIQPS VWVEPAVVIE VLADEITRSP VHTAGMNGEK 

       550        560        570        580 
QGYALRFPRL VSFRESDKRP EDATTVQEII EMYQQQAIKQ VAS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001825 Genomic DNA. Translation: ACZ42306.1.
RefSeqYP_003323128.1. NC_013525.1.

3D structure databases

ProteinModelPortalD1CBZ1.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ42306; ACZ42306; Tter_1400.
GeneID8645896.
KEGGttr:Tter_1400.
PATRIC32503032. VBITheTer68767_1496.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000036008.
KOK10747.
OMACTDIGEL.
OrthoDBEOG6Q8HXT.

Enzyme and pathway databases

BioCycTTER525904:GHMJ-1441-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1CBZ1_THET1
AccessionPrimary (citable) accession number: D1CBZ1
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: June 11, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)