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D1C9J4 (D1C9J4_SPHTD) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site471Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2791Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1451Substrate By similarity HAMAP-Rule MF_01201
Binding site3271Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue471N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D1C9J4 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 8B8E0701C04629F4

FASTA40842,280
        10         20         30         40         50         60 
MIEPFAARLA AAQGGAHALI DLDAFAGNIA YVRSQLPEGA EVIAVIKANA YGHGLVPCGR 

        70         80         90        100        110        120 
AALAAGASRL AVARIEEALL LRAAGVVAPI LVLSPANPAL ARQAAESGIA LAVGSATGLN 

       130        140        150        160        170        180 
RLLDALGDDL PPLPVHLKVD TGMHRFGVEP EGVVELARAL AREPRVRVEG VFTHFATADA 

       190        200        210        220        230        240 
ADDRVLQEQT RRFAAAVQAL AAAGLQPPLV HMANSAAILR GVVEIPAPRA TIAVRAGLIL 

       250        260        270        280        290        300 
YGLNPSRELP LPAPIRPVLR LVTRVGQVFT VPPGEGISYG WSYIAERPIR CANLPIGYAD 

       310        320        330        340        350        360 
GLVRLLSNQG WAVVGGAVCP IRGRICMDQT VIEVEAAPDV AEGDEAVLLS DGRDGAMTAD 

       370        380        390        400 
QAAALAGTIN YEIVSALAAR IPRVYLRGGR PVAVLDLLGL VEDPSAAC 

« Hide

References

[1]"The complete chromosome 2 of Sphaerobacter thermophilus DSM 20745."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., LaButti K.M., Clum A., Sun H.I., Brettin T., Detter J.C. expand/collapse author list , Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.F., Hugenholtz P., Woyke T., Wu D., Steenblock K., Schneider S., Pukall R., Goeker M., Klenk H.P., Eisen J.A.
Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 20745 / S 6022.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001824 Genomic DNA. Translation: ACZ40487.1.
RefSeqYP_003321309.1. NC_013524.1.

3D structure databases

ProteinModelPortalD1C9J4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ40487; ACZ40487; Sthe_3087.
GeneID8647026.
KEGGsti:Sthe_3087.
PATRIC32429012. VBISphThe120955_3112.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031444.
KOK01775.
OMALWQLEAI.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycSTHE479434:GHJN-3148-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1C9J4_SPHTD
AccessionPrimary (citable) accession number: D1C9J4
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: July 9, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)