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D1C9J4

- D1C9J4_SPHTD

UniProt

D1C9J4 - D1C9J4_SPHTD

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Protein
Alanine racemase
Gene
Sthe_3087
Organism
Sphaerobacter thermophilus (strain DSM 20745 / S 6022)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei47 – 471Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei145 – 1451Substrate By similarityUniRule annotation
Active sitei279 – 2791Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei327 – 3271Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciSTHE479434:GHJN-3148-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Sthe_3087Imported
OrganismiSphaerobacter thermophilus (strain DSM 20745 / S 6022)Imported
Taxonomic identifieri479434 [NCBI]
Taxonomic lineageiBacteriaChloroflexiSphaerobacteridaeSphaerobacteralesSphaerobacterineaeSphaerobacteraceaeSphaerobacter
ProteomesiUP000002027: Chromosome 2

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei47 – 471N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliD1C9J4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiLWQLEAI.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D1C9J4-1 [UniParc]FASTAAdd to Basket

« Hide

MIEPFAARLA AAQGGAHALI DLDAFAGNIA YVRSQLPEGA EVIAVIKANA    50
YGHGLVPCGR AALAAGASRL AVARIEEALL LRAAGVVAPI LVLSPANPAL 100
ARQAAESGIA LAVGSATGLN RLLDALGDDL PPLPVHLKVD TGMHRFGVEP 150
EGVVELARAL AREPRVRVEG VFTHFATADA ADDRVLQEQT RRFAAAVQAL 200
AAAGLQPPLV HMANSAAILR GVVEIPAPRA TIAVRAGLIL YGLNPSRELP 250
LPAPIRPVLR LVTRVGQVFT VPPGEGISYG WSYIAERPIR CANLPIGYAD 300
GLVRLLSNQG WAVVGGAVCP IRGRICMDQT VIEVEAAPDV AEGDEAVLLS 350
DGRDGAMTAD QAAALAGTIN YEIVSALAAR IPRVYLRGGR PVAVLDLLGL 400
VEDPSAAC 408
Length:408
Mass (Da):42,280
Last modified:January 19, 2010 - v1
Checksum:i8B8E0701C04629F4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001824 Genomic DNA. Translation: ACZ40487.1.
RefSeqiYP_003321309.1. NC_013524.1.

Genome annotation databases

EnsemblBacteriaiACZ40487; ACZ40487; Sthe_3087.
GeneIDi8647026.
KEGGisti:Sthe_3087.
PATRICi32429012. VBISphThe120955_3112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001824 Genomic DNA. Translation: ACZ40487.1 .
RefSeqi YP_003321309.1. NC_013524.1.

3D structure databases

ProteinModelPortali D1C9J4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACZ40487 ; ACZ40487 ; Sthe_3087 .
GeneIDi 8647026.
KEGGi sti:Sthe_3087.
PATRICi 32429012. VBISphThe120955_3112.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi LWQLEAI.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci STHE479434:GHJN-3148-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 20745 / S 6022.

Entry informationi

Entry nameiD1C9J4_SPHTD
AccessioniPrimary (citable) accession number: D1C9J4
Entry historyi
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: July 9, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi