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D1C2Z5 (D1C2Z5_SPHTD) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length314 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP By similarity. HAMAP-Rule MF_00182 SAAS SAAS005794

Catalytic activity

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet). HAMAP-Rule MF_00182 SAAS SAAS005794

Sequence similarities

Belongs to the Fmt family. HAMAP-Rule MF_00182

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential EMBL ACZ38612.1
Chain24 – 314291 Potential EMBL ACZ38612.1
PRO_5000537677

Regions

Region112 – 1154Tetrahydrofolate (THF) binding By similarity HAMAP-Rule MF_00182

Sequences

Sequence LengthMass (Da)Tools
D1C2Z5 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 3BBACF9AA3D417ED

FASTA31433,662
        10         20         30         40         50         60 
MAISVVFLGS PAFAVPSLRA LALDARFTIP LVVTQPDRPA GRGRRPRPPA VKDAAIELGL 

        70         80         90        100        110        120 
PVFQPETLRD PAAVERLAAA VPDVLVVVAY GEILRQSVLD LAPLGCLNVH PSLLPRYRGS 

       130        140        150        160        170        180 
SPVQAAILNG DTETGISIIK LVRRMDAGPI VAQRRVPLDG TETAGTLSER LANLAAEMLP 

       190        200        210        220        230        240 
DVVAAWVAGE LEAEPQDDAA ATYTRELTTA DARIDWGKDA AEIERLVRAM QPWPKAWSIL 

       250        260        270        280        290        300 
EGRRLAVLAC DISHKPSTEP PGTINVSARP PRVATGTTDL VLLRVQPEGK REMAAEDWAR 

       310 
GARLPHGARF APVE 

« Hide

References

[1]"The complete chromosome 1 of Sphaerobacter thermophilus DSM 20745."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., LaButti K.M., Clum A., Sun H.I., Brettin T., Detter J.C. expand/collapse author list , Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.F., Hugenholtz P., Woyke T., Wu D., Steenblock K., Schneider S., Pukall R., Goeker M., Klenk H.P., Eisen J.A.
Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 20745 / S 6022.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001823 Genomic DNA. Translation: ACZ38612.1.
RefSeqYP_003319434.1. NC_013523.1.

3D structure databases

ProteinModelPortalD1C2Z5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ38612; ACZ38612; Sthe_1176.
GeneID8638573.
KEGGsti:Sthe_1176.
PATRIC32425101. VBISphThe120955_1190.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000261177.
KOK00604.
OMARGDWFTP.
OrthoDBEOG6B09WV.

Enzyme and pathway databases

BioCycSTHE479434:GHJN-1202-MONOMER.

Family and domain databases

Gene3D3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPMF_00182. Formyl_trans.
InterProIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view]
PANTHERPTHR11138. PTHR11138. 1 hit.
PfamPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsTIGR00460. fmt. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD1C2Z5_SPHTD
AccessionPrimary (citable) accession number: D1C2Z5
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 14, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)