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Protein

Thymidine kinase

Gene

tdk

Organism
Xylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei87Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 16ATPUniRule annotation8
Nucleotide bindingi86 – 89ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciXCEL446471:G1GGQ-1940-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Xcel_1929Imported
OrganismiXylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07)Imported
Taxonomic identifieri446471 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesPromicromonosporaceaeXylanimonas
Proteomesi
  • UP000002255 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi446471.Xcel_1929

Structurei

3D structure databases

ProteinModelPortaliD1BTG9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107W53 Bacteria
COG1435 LUCA
HOGENOMiHOG000076391
KOiK00857
OMAiRATHNAR
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

D1BTG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAELVFFSGT MDSGKSTLAL QTDYNYAARG RTGLVFTRHD RAGAARISSR
60 70 80 90 100
LGLETDAREA DAATDFWELV AEEGRQGRPV DYLVCDEAQF YSPEQIEQLA
110 120 130 140 150
RLVDEVEIDV FAFGITTDFR TKLFPGSARL LELADRIEVL QVPALCWCGR
160 170 180 190 200
PATHQARTVD GVMVVEGEQV VVGDTAASAA VVAYEVLCRR HHMRRMTASS
210
ARQHATTDEA RLDLV
Length:215
Mass (Da):23,757
Last modified:January 19, 2010 - v1
Checksum:i2DCF6A74220C3DDC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001821 Genomic DNA Translation: ACZ30948.1
RefSeqiWP_012878690.1, NC_013530.1

Genome annotation databases

EnsemblBacteriaiACZ30948; ACZ30948; Xcel_1929
KEGGixce:Xcel_1929

Similar proteinsi

Entry informationi

Entry nameiD1BTG9_XYLCX
AccessioniPrimary (citable) accession number: D1BTG9
Entry historyiIntegrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: March 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health