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D1BT75 (D1BT75_XYLCX) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Xcel_1898
OrganismXylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07) [Complete proteome] [HAMAP]
Taxonomic identifier446471 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Promicromonosporaceae › Xylanimonas

Protein attributes

Sequence length626 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
D1BT75 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 0C16F613605B41B8

FASTA62666,593
        10         20         30         40         50         60 
MGLLAGISSP ADLRRLKPQQ LPALAAEIRD FLVHNVSRTG GHLGPNLGVV ELTLALHRVF 

        70         80         90        100        110        120 
ESPKDTFVFD TGHQSYVHKL LTGRQDFSAL RKQGGLSGYP SRTESEHDVV ENSHASTALS 

       130        140        150        160        170        180 
WADGIARANQ VRGFDDRHVI AVIGDGALTG GMAWEALNNI AESEDRRVII VVNDNGRSYS 

       190        200        210        220        230        240 
PTIGGLAHHL DTLRTTRGYE QFLGWGKRTL SRSGAPGRFA FQALHGLKKG LKDVVMPQGM 

       250        260        270        280        290        300 
FEDLGIKYIG PVDGHDEAAM ERALQRARDF GAPVIVHAIT EKGRGYTPAE QDVADRFHAV 

       310        320        330        340        350        360 
GRIHPETGLP VAPSRFGWTS VFADEIVRIG RRRPDVVAIT AAMLHPVGLA PFAAEFPERT 

       370        380        390        400        410        420 
FDVGIAEQHA ATSAAGMAFA GLHPVVAVYA TFLNRAFDQV LMDVALHKAG VTFVLDRAGL 

       430        440        450        460        470        480 
TGDDGASHNG MWDMAMLRIV PGLRLAAPRD EPTLRAALRT AVDVDDAPTV VRYPKGALVD 

       490        500        510        520        530        540 
DIPAVTELDG VDVIARHEGP DGARRVLVVG IGSMAGTALA TGEALAAHGL AVTVASPTWV 

       550        560        570        580        590        600 
LPVPAALVKL AGEADLVVTL EDGVVDGGIG SMLAQRSAEQ GITTPQVHRG IPLQFLDHAT 

       610        620 
RDQIAAATRL TAADATRDAL AALTPR

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References

[1]"The complete chromosome of Xylanimonas cellulosilytica DSM 15894."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Foster B., Clum A., Brettin T., Detter J.C., Han C. expand/collapse author list , Larimer F., Land M., Hauser L., Markowitz V., Cheng J.F., Hugenholtz P., Woyke T., Wu D., Gehrich-Schroeter G., Schneider S., Pukall S.R., Klenk H.P., Eisen J.A.
Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 15894 / CECT 5975 / LMG 20990 / XIL07.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001821 Genomic DNA. Translation: ACZ30917.1.
RefSeqYP_003326475.1. NC_013530.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8649428.
GenomeReviewsGene locus Xcel_1898 in contig CP001821_GR.
KEGGxce:Xcel_1898.
PATRIC32552813. VBIXylCel24446_1937.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQYDISYM.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1BT75_XYLCX
AccessionPrimary (citable) accession number: D1BT75
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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