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D1BQN8 (D1BQN8_VEIPT) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tryptophan synthase alpha chain HAMAP-Rule MF_00131 RuleBase RU000601
EC=4.2.1.20 HAMAP-Rule MF_00131 RuleBase RU000601
Gene names
Name:trpA HAMAP-Rule MF_00131
Ordered Locus Names:Vpar_0163
OrganismVeillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3) (Veillonella alcalescens) [Complete proteome] [HAMAP]
Taxonomic identifier479436 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Negativicutes › Selenomonadales › Veillonellaceae › Veillonella ›

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate By similarity. HAMAP-Rule MF_00131 RuleBase RU000601

Catalytic activity

L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O. HAMAP-Rule MF_00131 RuleBase RU000601 SAAS SAAS002028

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5. HAMAP-Rule MF_00131 RuleBase RU000601 SAAS SAAS002028

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP-Rule MF_00131 RuleBase RU000601

Sequence similarities

Belongs to the TrpA family. HAMAP-Rule MF_00131 RuleBase RU003662

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site441Proton acceptor By similarity HAMAP-Rule MF_00131
Active site551Proton acceptor By similarity HAMAP-Rule MF_00131

Sequences

Sequence LengthMass (Da)Tools
D1BQN8 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: C078BC144182DABE

FASTA26328,468
        10         20         30         40         50         60 
MSKIKDAFTK GKAFIPFISA GDHGIENTER YIRIMVKAGA DMVEIGIPFS DPTAEGPVIQ 

        70         80         90        100        110        120 
EASTRALSTG VKINDIFDMV RCLRTGEEAV TVPLVFMTYL NPIYVFGREK FFTLCEEVGI 

       130        140        150        160        170        180 
SGVIVPDMPF EEKGELASVA HKHGVEVVSL IAPTSENRIE MIAKDAEGFV YCVSSLGVTG 

       190        200        210        220        230        240 
MRSEIKTDIK SIVETIRKYT DIPVAVGFGI SKPEQAETMA RVSDGAIVGS AIVKIVAEHG 

       250        260 
EHADQALFDY VQSMKQAVLK AGA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001820 Genomic DNA. Translation: ACZ23851.1.
RefSeqYP_003311131.1. NC_013520.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ23851; ACZ23851; Vpar_0163.
GeneID8635607.
KEGGvpr:Vpar_0163.
PATRIC32529616. VBIVeiPar80537_0159.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000223816.
KOK01695.

Enzyme and pathway databases

UniPathwayUPA00035; UER00044.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00131. Trp_synth_alpha.
InterProIPR013785. Aldolase_TIM.
IPR011060. RibuloseP-bd_barrel.
IPR002028. Trp_synthase_suA.
[Graphical view]
PfamPF00290. Trp_syntA. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
TIGRFAMsTIGR00262. trpA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD1BQN8_VEIPT
AccessionPrimary (citable) accession number: D1BQN8
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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