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D1BQI7

- D1BQI7_VEIPT

UniProt

D1BQI7 - D1BQI7_VEIPT

Protein
Submitted name:

NAD-dependent epimerase/dehydratase

Gene

Vpar_0111

Organism
Veillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3) (Veillonella alcalescens)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (19 Jan 2010)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei35 – 351NADPImported
    Binding sitei40 – 401NADPImported
    Binding sitei55 – 551Chloride 3; via amide nitrogen
    Binding sitei58 – 581NADPImported
    Binding sitei80 – 801NADPImported
    Binding sitei84 – 841NADPImported
    Binding sitei128 – 1281NADPImported
    Binding sitei154 – 1541NADP; via amide nitrogenImported
    Binding sitei179 – 1791NADPImported

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi12 – 143NADPImported

    GO - Molecular functioni

    1. nucleotide binding Source: UniProtKB-KW

    Keywords - Ligandi

    NADPImported, Nucleotide-bindingImported

    Enzyme and pathway databases

    BioCyciVPAR479436:GHOS-114-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    NAD-dependent epimerase/dehydrataseImported
    Gene namesi
    Ordered Locus Names:Vpar_0111Imported
    OrganismiVeillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3) (Veillonella alcalescens)Imported
    Taxonomic identifieri479436 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesNegativicutesSelenomonadalesVeillonellaceaeVeillonella
    ProteomesiUP000007968: Chromosome

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3R6DX-ray1.25A2-218[»]
    4HNGX-ray1.50A1-218[»]
    4HNHX-ray1.58A/B1-218[»]
    4IPTX-ray1.55A1-218[»]
    ProteinModelPortaliD1BQI7.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiD1BQI7.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000262431.
    OMAiGHFTTAN.
    OrthoDBiEOG6R5C9T.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR016040. NAD(P)-bd_dom.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D1BQI7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYKYITILGA AGQIAQKLTA TLLTYTDMHI TLYGRQLKTR IPPEIIDHER    50
    VTVIEGSFQN PGKLEQAVTN AEVVFVGAME SGSDMASIVK ALSRKNIRRV 100
    IGVSMAGLSG EFPVALEKWT FDNLPISYVQ GERQARNVLR ESNLNYTILR 150
    LTWLYNDPEK TDYELIPEGA QFNDAQVSRE AVVKAIFDIL HAADETPFHR 200
    TSIGVGEPGT HYDKPSFH 218
    Length:218
    Mass (Da):24,384
    Last modified:January 19, 2010 - v1
    Checksum:i28C9D22E9D952388
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001820 Genomic DNA. Translation: ACZ23800.1.
    RefSeqiYP_003311080.1. NC_013520.1.

    Genome annotation databases

    EnsemblBacteriaiACZ23800; ACZ23800; Vpar_0111.
    GeneIDi8635554.
    KEGGivpr:Vpar_0111.
    PATRICi32529510. VBIVeiPar80537_0107.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001820 Genomic DNA. Translation: ACZ23800.1 .
    RefSeqi YP_003311080.1. NC_013520.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3R6D X-ray 1.25 A 2-218 [» ]
    4HNG X-ray 1.50 A 1-218 [» ]
    4HNH X-ray 1.58 A/B 1-218 [» ]
    4IPT X-ray 1.55 A 1-218 [» ]
    ProteinModelPortali D1BQI7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACZ23800 ; ACZ23800 ; Vpar_0111 .
    GeneIDi 8635554.
    KEGGi vpr:Vpar_0111.
    PATRICi 32529510. VBIVeiPar80537_0107.

    Phylogenomic databases

    HOGENOMi HOG000262431.
    OMAi GHFTTAN.
    OrthoDBi EOG6R5C9T.

    Enzyme and pathway databases

    BioCyci VPAR479436:GHOS-114-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei D1BQI7.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 10790 / DSM 2008 / JCM 12972 / Te3Imported.
    2. "Crystal structure of NAD-dependent epimerase/dehydratase from Veillonella parvula DSM 2008 with Cz-methylated lysine."
      Chang C., Hatzos-Skintges C., Clancy S., Joachimiak A.
      Submitted (MAR-2011) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS) OF 2-218.
    3. "The crystal structure of a short-chain dehydrogenases/reductase (wide type) from Veillonella parvula DSM 2008 in complex with NADP."
      Tan K., Hatzos-Skintges C., Clancy S., Joachimiak A.
      Submitted (OCT-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.58 ANGSTROMS) IN COMPLEX WITH NADP.
    4. "The crystal structure of a short-chain dehydrogenases/reductase (wide type) from Veillonella parvula DSM 2008."
      Tan K., Hatzos-Skintges C., Clancy S., Joachimiak A.
      Submitted (OCT-2012) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS).
    5. "The crystal structure of a short-chain dehydrogenases/reductase (ethylated) from Veillonella parvula DSM 2008."
      Tan K., Hatzos-Skintges C., Clancy S., Joachimiak A.
      Submitted (JAN-2013) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS).

    Entry informationi

    Entry nameiD1BQI7_VEIPT
    AccessioniPrimary (citable) accession number: D1BQI7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 19, 2010
    Last sequence update: January 19, 2010
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3