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D1BLG8

- D1BLG8_VEIPT

UniProt

D1BLG8 - D1BLG8_VEIPT

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Protein

3-deoxy-manno-octulosonate cytidylyltransferase

Gene

kdsB

Organism
Veillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3) (Veillonella alcalescens)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.UniRule annotationSAAS annotation

Catalytic activityi

CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. 3-deoxy-manno-octulosonate cytidylyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-UniPathway
  2. keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciVPAR479436:GHOS-559-MONOMER.
UniPathwayiUPA00030.
UPA00358; UER00476.

Names & Taxonomyi

Protein namesi
Recommended name:
3-deoxy-manno-octulosonate cytidylyltransferaseUniRule annotation (EC:2.7.7.38UniRule annotation)
Alternative name(s):
CMP-2-keto-3-deoxyoctulosonic acid synthaseUniRule annotation
Gene namesi
Name:kdsBUniRule annotation
Ordered Locus Names:Vpar_0542Imported
OrganismiVeillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3) (Veillonella alcalescens)Imported
Taxonomic identifieri479436 [NCBI]
Taxonomic lineageiBacteriaFirmicutesNegativicutesSelenomonadalesVeillonellaceaeVeillonella
ProteomesiUP000007968: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliD1BLG8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KdsB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000007602.
KOiK00979.
OMAiDDQRIAD.
OrthoDBiEOG6KT2SK.

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
HAMAPiMF_00057. CMP_KDO_synth.
InterProiIPR003329. Cytidylyl_trans.
IPR004528. KdsB.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PANTHERiPTHR21485:SF4. PTHR21485:SF4. 1 hit.
PfamiPF02348. CTP_transf_3. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
TIGRFAMsiTIGR00466. kdsB. 1 hit.

Sequencei

Sequence statusi: Complete.

D1BLG8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKFGCVIPAR YGSTRLPGKP LADIAGKPMI ERVYARVSQA TKTVCTIVAT
60 70 80 90 100
DDNRVYSAVQ QFGGTVMMTD PNHPTGTDRL AEVASHYTDL DVVINVQGDE
110 120 130 140 150
PMIDPNLIDD LARLFEEDPN LQMATVATPL LEEEYEEPSA VKVILNNRND
160 170 180 190 200
AMYFSRSLIP YPRHDFVRPP LKHIGIYAYR REFLLNYAKM EPTPAERTES
210 220 230 240
LEQLRALENG YTIRVILTNK RFIGVDTPED LARVNAIYEQ EEK
Length:243
Mass (Da):27,522
Last modified:January 19, 2010 - v1
Checksum:i76A172FD72E43C3B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001820 Genomic DNA. Translation: ACZ24225.1.
RefSeqiYP_003311505.1. NC_013520.1.

Genome annotation databases

EnsemblBacteriaiACZ24225; ACZ24225; Vpar_0542.
GeneIDi8635999.
KEGGivpr:Vpar_0542.
PATRICi32530378. VBIVeiPar80537_0528.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001820 Genomic DNA. Translation: ACZ24225.1 .
RefSeqi YP_003311505.1. NC_013520.1.

3D structure databases

ProteinModelPortali D1BLG8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACZ24225 ; ACZ24225 ; Vpar_0542 .
GeneIDi 8635999.
KEGGi vpr:Vpar_0542.
PATRICi 32530378. VBIVeiPar80537_0528.

Phylogenomic databases

HOGENOMi HOG000007602.
KOi K00979.
OMAi DDQRIAD.
OrthoDBi EOG6KT2SK.

Enzyme and pathway databases

UniPathwayi UPA00030 .
UPA00358 ; UER00476 .
BioCyci VPAR479436:GHOS-559-MONOMER.

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
HAMAPi MF_00057. CMP_KDO_synth.
InterProi IPR003329. Cytidylyl_trans.
IPR004528. KdsB.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view ]
PANTHERi PTHR21485:SF4. PTHR21485:SF4. 1 hit.
Pfami PF02348. CTP_transf_3. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 1 hit.
TIGRFAMsi TIGR00466. kdsB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10790 / DSM 2008 / JCM 12972 / Te3Imported.

Entry informationi

Entry nameiD1BLG8_VEIPT
AccessioniPrimary (citable) accession number: D1BLG8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: October 29, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3