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D1BLG8

- D1BLG8_VEIPT

UniProt

D1BLG8 - D1BLG8_VEIPT

Protein

3-deoxy-manno-octulosonate cytidylyltransferase

Gene

kdsB

Organism
Veillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3) (Veillonella alcalescens)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (19 Jan 2010)
      Previous versions | rss
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    Functioni

    Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.UniRule annotationSAAS annotation

    Catalytic activityi

    CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.UniRule annotationSAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. 3-deoxy-manno-octulosonate cytidylyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-UniPathway
    2. keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    NucleotidyltransferaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    Lipopolysaccharide biosynthesisUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciVPAR479436:GHOS-559-MONOMER.
    UniPathwayiUPA00030.
    UPA00358; UER00476.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    3-deoxy-manno-octulosonate cytidylyltransferaseUniRule annotation (EC:2.7.7.38UniRule annotation)
    Alternative name(s):
    CMP-2-keto-3-deoxyoctulosonic acid synthaseUniRule annotation
    Gene namesi
    Name:kdsBUniRule annotation
    Ordered Locus Names:Vpar_0542Imported
    OrganismiVeillonella parvula (strain ATCC 10790 / DSM 2008 / JCM 12972 / Te3) (Veillonella alcalescens)Imported
    Taxonomic identifieri479436 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesNegativicutesSelenomonadalesVeillonellaceaeVeillonella
    ProteomesiUP000007968: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Structurei

    3D structure databases

    ProteinModelPortaliD1BLG8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the KdsB family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000007602.
    KOiK00979.
    OMAiDDQRIAD.
    OrthoDBiEOG6KT2SK.

    Family and domain databases

    Gene3Di3.90.550.10. 1 hit.
    HAMAPiMF_00057. CMP_KDO_synth.
    InterProiIPR003329. Cytidylyl_trans.
    IPR004528. KdsB.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view]
    PANTHERiPTHR21485:SF4. PTHR21485:SF4. 1 hit.
    PfamiPF02348. CTP_transf_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF53448. SSF53448. 1 hit.
    TIGRFAMsiTIGR00466. kdsB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D1BLG8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFGCVIPAR YGSTRLPGKP LADIAGKPMI ERVYARVSQA TKTVCTIVAT    50
    DDNRVYSAVQ QFGGTVMMTD PNHPTGTDRL AEVASHYTDL DVVINVQGDE 100
    PMIDPNLIDD LARLFEEDPN LQMATVATPL LEEEYEEPSA VKVILNNRND 150
    AMYFSRSLIP YPRHDFVRPP LKHIGIYAYR REFLLNYAKM EPTPAERTES 200
    LEQLRALENG YTIRVILTNK RFIGVDTPED LARVNAIYEQ EEK 243
    Length:243
    Mass (Da):27,522
    Last modified:January 19, 2010 - v1
    Checksum:i76A172FD72E43C3B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001820 Genomic DNA. Translation: ACZ24225.1.
    RefSeqiYP_003311505.1. NC_013520.1.

    Genome annotation databases

    EnsemblBacteriaiACZ24225; ACZ24225; Vpar_0542.
    GeneIDi8635999.
    KEGGivpr:Vpar_0542.
    PATRICi32530378. VBIVeiPar80537_0528.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001820 Genomic DNA. Translation: ACZ24225.1 .
    RefSeqi YP_003311505.1. NC_013520.1.

    3D structure databases

    ProteinModelPortali D1BLG8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACZ24225 ; ACZ24225 ; Vpar_0542 .
    GeneIDi 8635999.
    KEGGi vpr:Vpar_0542.
    PATRICi 32530378. VBIVeiPar80537_0528.

    Phylogenomic databases

    HOGENOMi HOG000007602.
    KOi K00979.
    OMAi DDQRIAD.
    OrthoDBi EOG6KT2SK.

    Enzyme and pathway databases

    UniPathwayi UPA00030 .
    UPA00358 ; UER00476 .
    BioCyci VPAR479436:GHOS-559-MONOMER.

    Family and domain databases

    Gene3Di 3.90.550.10. 1 hit.
    HAMAPi MF_00057. CMP_KDO_synth.
    InterProi IPR003329. Cytidylyl_trans.
    IPR004528. KdsB.
    IPR029044. Nucleotide-diphossugar_trans.
    [Graphical view ]
    PANTHERi PTHR21485:SF4. PTHR21485:SF4. 1 hit.
    Pfami PF02348. CTP_transf_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53448. SSF53448. 1 hit.
    TIGRFAMsi TIGR00466. kdsB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 10790 / DSM 2008 / JCM 12972 / Te3Imported.

    Entry informationi

    Entry nameiD1BLG8_VEIPT
    AccessioniPrimary (citable) accession number: D1BLG8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 19, 2010
    Last sequence update: January 19, 2010
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3